561 zoekresultaten voor “mouse models” in de Publieke website
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Leiden econophysics model tested best by central banks
A full overview of all loans and debts between banks would help preventing a new financial collapse. But banks do not provide this information. An econophysics model by Diego Garlaschelli and collaborators reconstructs the most probable situation and finishes first place in two independent tests.
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Computer models chart extensive Caribbean inter-island networks
The precolonial inhabitants of the Caribbean islands communicated, travelled, and exchanged objects and ideas along an expansive inter-island network. New methods of computer modeling shed light on these networks. Emma Slayton is set to discuss her work on this topic at her Defense on the 12th of Se…
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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New Business models for the Legal Services Market
Linking Empirical Academic thinking with Legal Practice. Internationally and particularly in the Netherlands. By René Orij, April, 2016.
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Simulating the prehistoric use of fire through computer models
Archaeologists often use the percentages of heat-affected stone or bone artifacts found at archaeological sites as a way to determine how frequently fire was used by the inhabitants. Andrew Sorensen and Fulco Scherjon have come up with a computer model called 'fiReproxies' to simulate how fires used…
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Leiden: The scene of the Zebrafish Disease Models conference 2018
In July, 2018, the Institute of Biology Leiden hosted the 11th conference of the Zebrafish Disease Models Society (ZDMS), an international association dedicated to the advancement of basic and clinical research using zebrafish disease models. More than 350 researchers from all over the world gathered…
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New vegetation models can improve climate change predictions
A new study in Nature Plants has explored the most important organising principles that control vegetation behaviour. The insights from this study can be used to improve predictions on climate change. Leiden scientists Peter van Bodegom and Nadia Soudzilovskaia participated in the study.
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Key publications
Key publications of the Systems Pharmacology group
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Vasiliki Lagari
Faculteit Archeologie
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Verónica Mäki-Marttunen
Faculteit der Sociale Wetenschappen
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Tales Yamamoto
Wiskunde en Natuurwetenschappen
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Warisa Bunmahotama
Warisa started as a Postdoc researcher at the Department of Environmental Biology of CML in March 2020.
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Saskia Heijnen
Faculteit der Sociale Wetenschappen
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Eiko Fried
Faculteit der Sociale Wetenschappen
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Zsuzsa Bakk
Faculteit der Sociale Wetenschappen
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Roy de Kleijn
Faculteit der Sociale Wetenschappen
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A mathematical model for a more diverse workforce
Many organisations have a biased workforce, even though diversity has so many advantages. Australian and Dutch researchers, including Leiden psychologist Romy van der Lee, have developed a solution based on a mathematical model. They published their findings in PLoS One on 28 July.
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How brain disorder models are like the Night Watch
Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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HomininSpace – a large scale simulation system for hominins in the past
HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…
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Pasteurs Cube: a new model for classifying academic researchers?
Applying a three-dimensional framework of research-related activities, Pasteur’s Cube helps to describe and study ‘use inspired’ academics at today’s research-intensive universities.
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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More efficient drug development with the help of computer models
The coronavirus has the world in its grip. Finding a cure has never been more important. Unfortunately, the development of new drugs for treatment of the COVID-19 disease caused by the virus and development of a vaccine are complex, lengthy, and above all costly processes. With the help of computer…
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New model predicts ‘yoyo’ orbits around black holes
Stars orbit black holes while jumping up and down. This is the prediction of a theoretical model developed by Leiden physicist Satish Kumar Saravanan, based on Einstein’s theory of relativity. He defends his PhD thesis on July 7th.
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Galaxy formation and the structure of the Universe
Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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Advances in Survival Analysis and Optimal Scaling Methods
This thesis is based on five papers on several topics.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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Rosaleen March
Wiskunde en Natuurwetenschappen
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Ruben Huele
Wiskunde en Natuurwetenschappen
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Sebastiaan Deetman
Wiskunde en Natuurwetenschappen
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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Jinhui Zhou
Wiskunde en Natuurwetenschappen
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Amie Corbin
Wiskunde en Natuurwetenschappen
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Viktor Pirmana
Wiskunde en Natuurwetenschappen