Four Leiden researchers have each been awarded a consolidator grant of up to 2 million euros by the European Research Council (ERC). They carry out research on a diverse range of subjects, from gender stereotyping in the field of science to making sugar molecules.

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…

As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.

Which plant leaf characteristics are involved in thrips resistance in tomato?

Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.

Researchers at Leiden University Medical Center (LUMC) and Radboud university medical center have been given the green light to deliberately infect volunteers with malaria in order to test a highly promising vaccine on them.

The pandemic has challenged us to revisit the way we structure education and how to reach out to students remotely. It almost seems fitting that a course devoted to a topic so closely related to the context of the corona crisis, that of global health, would explore the possibilities of making the course…

The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?

Promotor: S.M. Verduyn Lunel

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.

A multi-disciplinary approach to past lifestyles and cultural practices

What is the function of the insect serosa?

Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Can drug screening for tuberculosis treatment be made more efficient?

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…

A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

Heart patients who maintain a healthy lifestyle can start earning discounts at shops or for trips out. The Tergooi Hospital is the first in the Netherlands to introduce this unique method that was co-developed by the research group headed by Professor of Health Psychology Andrea Evers and the Leiden…

Lezing, History Brown Bag Seminar

Oratie

Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

We examine how soil inoculation influences aboveground organisms (i) directly, and indirectly via (ii) its effects on plant chemistry or volatile emission, or via (iii) mediating the effects of belowground pathogens on aboveground organisms via the shared plant.

Many dangerous diseases such as COVID-19, Ebola and Q fever have jumped from animals to humans. But it is not only because of these diseases that we should include animals in our health policy, but also because of their right to health, writes PhD candidate Joachim Nieuwland. PhD defence on 13 May.

Four scientists from the Faculty of Science will receive a grant of up to 50,000 euros in the Open Competition Domain Science - XS from science financier NWO. This category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.…

Congres/symposium

No two pandemics are ever the same. The current coronavirus crisis, for instance, is clearly very different from the deadly plague outbreaks in the 14th and 15th centuries. Can historians learn anything from the coronavirus crisis? And what can we learn at the moment from historians? These are questions…

With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.

Utilization of plant-originated products as new antibiotics

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

The Horizon 2020 project ImageInLife has started on 1 January, followed by a kick-off meeting at the coordinating University of Montpellier at the end this month. This Marie Skłodowska-Curie training network brings together European groups that work on the imaging of vertebrates and offers fourteen…

Leiden University is partner of the Netherlands Centre for One Health (NCOH). This initiative brings together leading academic research institutes in the Netherlands in an open innovation network that responds to the theme: One Health. NCOH interviewed Doris van Bergeijk: PhD student of the project…

This year, two Leiden master students will be awarded a KNMP Student Award. Both Wisse van Os and Jip Linthorst will receive 1,000 euros from the Royal Dutch Pharmacists Association (KNMP) as a reward for their excellent study results, motivation and commitment.

For the first time, research has been conducted on how the health of detained persons prior to their detention differs from that of non-detainees and to what extent health problems change over the period: from before and after their detention.

Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.