According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Zand, hout en fossiele brandstoffen: uit cijfers van het CBS blijkt dat Nederlanders steeds minder grondstoffen gebruiken. In het radioprogramma ‘Geld of je leven’ op Radio 1 geeft Industrieel Ecoloog René Kleijn zijn visie op de ontwikkelingen.

Hoe kunnen we onze maatschappij zo inrichten dat de wereld leefbaar blijft voor onszelf en al het andere leven om ons heen? Aan dat vraagstuk werken Leidse wetenschappers samen vanuit allerlei disciplines, van biologie tot datawetenschap en van milieueconomie tot archeologie.

Promotores: F.H.J. Redig, W.T.F. den Hollander

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Promotor: G.P. van Wezel

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Promotores: F.H. van Lunteren, F.P. Israel

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Heb jij een bachelordiploma op zak en wil je een masteropleiding volgen aan een Nederlandse universiteit van wereldklasse? Met bijna 80 masteropleidingen vind je bij de Universiteit Leiden de master die bij je past.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

Tin electrodeposition applications have rapidly evolved in the past 25 years.

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Tijdens de studie Molecular Science & Technology leren studenten te werken aan schonere en efficiëntere processen en worden zij opgeleid om nieuwe technologieën te ontwikkelen als antwoord op de uitdagingen van de toekomst: de groeiende vraag naar nieuwe producten en milieuvriendelijke processen. Bij…

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Promotor: Richard D. Gill

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

Mechanical interactions between cells and their environment play an important role in many biological processes.

Promotie

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Overall dispersion in LCA as result of inherent uncertainties, spread and unrepresentativeness.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Control of infectious diseases poses continuous challenges for human health.

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

The research programme Cities, Migration and Global Interdependence 1350-2000 (CMGI) focuses on urbanisation, migration, and economic development in a comparative and global context.

How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?

Het Centrum voor Milieuwetenschappen (CML) is een instituut van de faculteit Wiskunde en Natuurwetenschappen aan de Universiteit Leiden.

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

Machine Learning is becoming a more and more substantial technology for industry.

Possible improvements for the assessment of abiotic depletion in LCA.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

Wil jij de beste redenen weten waarom je een master aan de Universiteit Leiden moet volgen? Of hoe het is om te studeren in Leiden of Den Haag? Onze studenten vertellen je over hun studie aan de Universiteit Leiden.

Wil jij de beste redenen weten waarom je een master aan de Universiteit Leiden moet volgen? Of hoe het is om te studeren in Leiden of Den Haag? Onze studenten vertellen je over hun studie aan de Universiteit Leiden.

Promotor: Prof.dr. E. F. van Dishoeck