Deze master specialisatie behandelt een breed scala aan wetenschappelijke onderwerpen, waaronder High Energy Physics and Particle Cosmology, Theoretical Physics of Life Processes en Condensed Matter Theory.

This thesis presents the anharmonic infrared spectra of a series of polycyclic aromatic hydrocarbons. Comparisons and characterizations are made based on high-resolution low-temperature gas-phase experimental spectra.

The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

This thesis describes the design, characterization and application of dextran based crosslinked network.

Promotores: J.C. van Houwelingen, S.A. van de Geer

Heart failure is a major health care problem with high mortality.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Promotor: B.van de Water, Co-promotor: L.S.Price

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

What is the environmental impact, the human health impact and the life cycle and production costs of the lab, pilot and commercial diffusion of nanowires and nanowire-based photovoltaic technologies?

Onderzoekers van LIACS werken aan het bedenken van de computers van morgen die de ruggengraat zullen vormen van de Cloud en Edge computing paradigma’s en ‘the Internet of Things’. In dit verband zijn we betrokken bij onderzoek en ontwikkeling van high performance computing systemen, embedded & real-time…

Chronische pijn, misselijkheid of braken door chemotherapie. Als je er last van hebt, kan medicinale cannabis een uitkomst zijn. Het nadeel is alleen wel dat patiënten er high van kunnen worden. Leidse onderzoekers van het Oncode Instituut doen daarom onderzoek naar alternatieven waar je dat niet van…

The dissertation describes TEM experiments on heterogeneous catalysts.

Promotie

Festival

Het Leidse natuurkunde-instituut heeft de jaarlijkse conferentie georganiseerd van de Nederlandse Vacuümvereniging (NEVAC). Experts uit het veld van vacuümexperimenten vertelden over hun onderzoek. De 2016 NEVAC-prijs ging naar de Eindhovense promovendus Martijn Vos.

Promotie

Promotie

Promotie

Promotie

Promotie

Promotie

Promotie

Promotie

Dr. Charlene Kalle and dr. Tim van Erven, both assistant professors at the Mathematical Institute of Leiden University have received a TOP grant for Physical Sciences from the NWO (The Netherlands Organization for Scientific Research).

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…

Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

This article 'Shaping the European External Action Service and its post-Lisbon crisis management structures: an assessment of the EU High Representatives’ political leadership' assesses the role, influence and core aspects of the EU High Representatives’ (HR/VPs) “political leadership” in the context…

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.