A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

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Promotor: Prof.dr. B.R. Katzy, Prof.dr. J. de Vries

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

HIIT staat voor High Intensity Interval Training, een term die we de laatste tijd steeds vaker in de fitness tegenkomen. High Intensity Interval Training of HIIT, is een circuit gebaseerde high energy mix van cardio- en krachtoefeningen. Wetenschappelijk is bewezen dat dit een van de meest effectieve…

Het Leiden Leadership Centre is lid van de Global Leadership Centres Roundtable (GLCR). De Global Leadership Centres Roundtable is het internationale netwerk van universitaire leiderschapscentra.

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Promotor: Prof.dr. E. Deprettere

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

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This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotor: Prof.dr.ir. E. Deprettere

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

Als wetenschappelijke partner biedt het Sport Data Center (sport)organisaties een aantal diensten.

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

In unconventional high temperature superconductors, supercurrent vortices are known to spoil the Landau levels. In this thesis the emergence of Landau levels is studied in different types of superconductors: Weyl superconductors, and the Fu-Kane heterostructure.

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Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

De faciltieit ontwikkelt en gebruikt, high-throughputmethoden toe voor genomisch onderzoek.

In onderstaand overzicht bevindt zich alle informatie per vak welke door de afdeling Bedrijfswetenschappen wordt verzorgd. Als u op een vak klikt, wordt u doorgeleid naar de studiegids. Hierin vindt u alle informatie over het betreffende vak.

Migration imposes special pressures on the meaning, experience and organization of lifecycle rituals. These pressures are felt most strongly by Muslim migrants to Western Europe. In this innovative study, Nathal M. Dessing examines the effects of migration on the life cycle rituals of Moroccan, Turkish…

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Door het volgen van een master vergroot je je kansen op de arbeidsmarkt. Na de driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master bij de Universiteit Leiden of een andere instelling.

Door het volgen van een master vergroot je je kansen op de arbeidsmarkt om een baan op niveau te vinden. Na de driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master bij de Universiteit Leiden of een andere instelling.

Door het volgen van een master vergroot je je kansen op de arbeidsmarkt om een baan op niveau te vinden. Na de driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master bij de Universiteit Leiden of een andere instelling.

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

The LUGO Press is a student publication forum, rooted in academia and journalistic practices and published by the Leiden University Green Office.

In het onderzoeksprogramma Drug Discovery & Safety zijn we geïnteresseerd in de werkzaamheid en veiligheid van nieuwe medicijnen en nieuwe manieren om deze aspecten te bepalen. Daarvoor combineren we geavanceerde imaging en high-throughput screening technieken met computationele aanpakken zoals chem-…