646 zoekresultaten voor “gut immune homeostasis” in de Publieke website
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‘Skin injection could allow us to vaccinate up to five times more people from the same supplies’
The current COVID-19 vaccination campaign involves injecting the vaccine into muscle tissue, but injecting a smaller amount of vaccine in the skin might also provide good protection. The #wakeuptocorona crowdfunding campaign has enabled Anna Roukens (LUMC) to examine the safety and efficacy of vaccination…
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Thomas Michiels
There are a number of vaccines that require animal testing in their production. Thomas Michiels developed a replacement lab test that allows manufacturers to achieve the same result, without involving animals. The next step is that the test has to be validated by pharmaceutical companies and has to…
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The Evolution of Human Diet, Health and Lifestyle
Research into the evolutionary backgrounds of our diets can help us make the right choices in diet, health and lifestyle.
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St. Eustatius
From 20 June to 12 August 2011 a team from the Caribbean Research Group, Faculty of Archaeology, Leiden University and the St. Eustatius Centre for Archaeological Research (SECAR) under the direction of Dr. Grant Gilmore III, Dr. Menno Hoogland, Prof. Corinne Hofman and Dr. Alice Samson carried out…
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HARVEST: Plant foods in human evolution
The HARVEST project explores the dietary choices that our hominin ancestors and relatives made, by recovering information on what they consumed, and how factors like environmental variation, intrinsic biology, and development of food processing technologies could have influenced their decisions.
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LUMC professor Maria Yazdanbakhsh receives Spinoza Prize
Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…
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Amanda Foks receives Dekker grant from Dutch Hartstichting
Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.
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Neuropsychiatric symptoms and immune system parameters in Huntington's Disease
Promotie
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Natural and Vaccine derived immunity against the human papillomavirus
Promotie
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Characterization of innate immune cells in the glioma microenvironment
Promotie
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Characterization of innate immune cells in the glioma microenvironment
Promotie
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T and NK cell immunity after hematopoietic stem cell transplantation
Promotie
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Immune cell complexity in the tumor microenvironment of breast cancer
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Immunochemical approaches to monitor and modulate the adaptive immune system
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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In vivo fluorescence imaging of IgG1 aggregates after subcutaneous and intravenous injection in mice
PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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International organisations and the rule of law
International organisations that represent collaborations between States are becoming increasingly more powerful, and they have an increasing impact on our daily lives. For example, the European Court of Human Rights in Strasburg established that minors have a right to legal aid immediately following…
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Functional aspects of the adaptive immune system in arthritis
Promotie
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Implications of memory CD8 T cell quality for protective immunity
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Tracking helminths: from molecular diagnostics to mechanisms behind immune polarization
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Mechanisms of immune evasion in Epstein-Barr virus infection
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Modulation of the immune system for treatment of atherosclerosis
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The interplay between lipids and the immune system in atherosclerosis
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Systems Vaccinology – Molecular signatures of immunity to Bordetella pertussis
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Boosting the host immune system to fight tuberculosis
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Pulling the strings on anti-cancer immunity
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Research
An overview of the research at the Biologics Formulation group
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Two NWO ECHO grants for Leiden Chemistry
Two excellent young chemists, Jeroen Codée and Sander van Kasteren, have received an ECHO grant for €260,000 from the Netherlands Organisation for Scientific Research (NWO). This funding will allow them to begin their research projects.
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Placebo research: Pharmacological conditioning
The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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Iron-immune interactions in Alzheimer's disease
Promotie
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Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
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New generation alum based vaccine adjuvants
Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.
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Lab facilities Health, Medical and Neuropsychology
Psycho-physiological studies for health and disease.
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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New techniques for tuberculosis treatment
About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.
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Leiden students develop highly contagious card game
Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…
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Nostalgia for the Present
Ethnography and Photography in a Moroccan Berber Village
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Topic: Stress and stress-related disorders
The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…
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Exposed to events that never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Information activities
Do you want to know more about the research master's specialisation Clinical and Health Psychology and what it's like to study in Leiden? Leiden University offers several information activities to help you choose a master's programme.
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Welcome to the Leiden University Faculty of Social and Behavioural Sciences
The Faculty of Social and Behavioural Sciences brings together high-quality research and outstanding teaching.
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…