Promotores: K.J. Batenburg, B. Koren

In this thesis we study products of linear error correcting codes.

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The results of the investigations by citizens are used in an innovative research project that investigates the potential of machine learning and automated detection in archaeology.

On 8 January 2020, Jelmer Brouwer defended his thesis 'Detection, detention, deportation'. The doctoral research was supervised by Prof. J.P. van der Leun and Prof. M.A.H. van der Woude.

Our group explores the larger domain of quantum measurement. In particular we investigate two themes that are closely connected: The detection of specially prepared quantum states of light and understanding and characterizing quantum photon detectors.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

In this project we develop algorithms to automatically detect a particular type of archaeological sites in satellite images of the Alps.

Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood

Novel algorithms to detect indels and structural variants from next- and third-generation sequencing data.

Promotor: Prof. dr. I. Snellen, Co-Promotor: Dr. M. Kenworthy

Promotor: E. Bouwman Co-Promotor: S. Bonnet

So far it has been impossible to compare large sets of syntactic constructions in large sets of languages systematically and automatically. The online availability of parallel text corpora and software tools to align, enrich, search and analyse them has the potential to make automatic massive systematic…

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

Cursus, Summer Programme

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

This online advanced summer programme focuses on the field of preventing, detecting and responding to violent extremism and gives insight in the opportunities and challenges of various approaches.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Generally the data from remote sensing surveys - the scanning of the earth by satellite or aircraft in order to obtain information about it - is screened manually in archaeology. However, constant monitoring of the earth's surface causes a huge influx of data of high complexity and high quality. To…

How do nanoparticles bioaccumulate and biodistribute in organisms?

In Qualtrics, students can no longer access their data.

It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

Metamaterials have properties that depend on their shape and architecture. Researchers at AMOLF, Leiden University and Tel Aviv University have found a new way of designing these metamaterials and their properties by deliberately incorporating small errors. They publish their results today in Nature…

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

In a recent TEDx Flanders event “Statistical Errors in Court”, Statistical Scientist Richard Gill speaks about the case of Lucia de Berk, a nurse found guilty of several murders based largely on statistics.

For his PhD project, computer scientist Manolis Fragkiadakis is developing a tool that can compare videos of sign language corpora. This would make it possible to detect differences between sign languages and prevent translation errors. Ultimately, the tool could be used to compare sign languages from…

When new features are being written into software code, errors can easily be made. This causes bugs, which leads to software appearing later and being more expensive. Michiel Helvensteijn, a PhD student from CWI and the Leiden Institute of Advanced Computer Science, studied how to prevent these kinds…

Ariane Briegel wants to use bacteria to detect cancer at an early stage. Together with postdoc Alise Muok, she is developing a method to quickly and cheaply test the urine of patients for the presence of suspicious molecules. They receive a grant of approximately 150,000 euros from the Dutch Cancer…

Leiden and Jülich researchers discovered an elegant and simple approach to improve the sensitivity of graphene biosensors. These so-called ‘next generation graphene electronic biochemical sensor devices’ are able to detect very low amounts of HIV DNA thanks to their very low electronic noise.

It's pretty hard to spot a single 5 nanometer particle. Leiden physicists pulled it off by turning a 120 nm gold rod into a detector.

NWO honoured Leiden psychologist Jeffrey Durieux with a Research Talent Grant for early dementia detection by identifying differences in resting-state networks.

Over the past decades within the European Union (EU), economic proliferation and globalisation have resulted in an increase in transboundary waste transportation. Although waste trading can often have positive economic and environmental impacts by repurposing natural resources within industrial sectors,…

Physicists, including Leiden researcher, Sanli Faes, have devised a new technique for studying processes at microscale rapidly and extremely precisely. This new method will make it easier to develop antiviral medication. And it doesn’t stop there. Publication in ACS Nano.

Is it possible to diagnose diseases using molecular switches? The new international consortium LogicLab will address this question. Leiden chemist Sylvestre Bonnet and Leiden pharmacologist Thomas Hankemeier are involved in the project. LogicLab will run for four years and will receive over 3.5 million…

Optical detection of a single electron using a single molecule has never been done. Leiden physicist Michel Orrit and his team have now identified a molecule that is sensitive enough to detect an electron at a distance of hundreds of nanometers. The results are published as a cover article in ChemPh…

Empathic or anxious mistakes? A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

For many years, scientists have observed a correlation between Alzheimer’s disease and a surplus of iron in the brain. However, a causal link between the two has not been proven yet. We lack knowledge concerning the specific form of iron that is involved in the development of neurodegenerative diseases.…

Leiden physicists have managed to detect a single molecule called dibenzoterrylene in a new crystal, and found that it is a candidate component for a quantum network. Future quantum computers will need such a network to work together while maintaining their advantages. Publication in ChemPhysChem jo…

By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…

Promotor: A.W. van der Vaart

Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe

Promotor: Prof.dr. K.J. Batenburg

Lezing

The Bioinformatics and Genomics Core provides bioinformatics advice and genotyping services. The researchers that lead and work for this facilities are experts in their fields and are available for consultation regarding experimental design and interpretation of results.

Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)

Prof.dr. Annelou van Gijn has obtained a Marie Curie subsidy for research on wetland activity patterns in Mesolithic Northwest Europe. This funding has been used to employ the researcher dr. Aimée Little. The project will commence in November 2011.

Physicists propose the existence of sterile neutrinos that would explain three big mysteries in nature. To actually find them in particle accelerators, researchers need to know how they are produced and how they decay. PhD candidate Kyrylo Bondarenko has made predictions about this, which are currently…

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.