There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Promotor: T. Schmidt

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Promotor: J.W.M. Frenken

Wiskunde en Natuurwetenschappen

Electron microscopy has become an extremely important techniquein a wide variety of elds.

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

The dissertation describes TEM experiments on heterogeneous catalysts.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen

Op 9 mei 2018 verdedigde Roy van Keulen zijn proefschrift 'Digital Force: Life, Liberty & Livelihood in the Information Age'. Het promotieonderzoek is begeleid door promotor prof.dr. A. Ellian.

Wiskunde en Natuurwetenschappen, Leids Instituut voor Onderzoek in de Natuurkunde (LION)

Hoe kan wrijving op de nanoschaal gereduceerd worden?

Political scientist Corinna Jentzsch (Leiden University) about the organisation of rebel and government auxiliaries in the civil war in Mozambique (1976–1992).

Promotor: B. van de Water

Promotor: B. van de Water

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Een verhaal van Twee Mosuls, De wederopstand van de Irakese strijdkrachten en de militaire nederlaag van ISIS. In dit artikel, gepubliceerd in het Journal of Strategic Studies, bespreken de auteurs Maarten Broekhof, Martijn Kitzen en Frans Osinga de militaire aanpassing door de Iraakse strijdkrachten…

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Promotie

Deze week viert de Europese onderzoeksraad (ERC) haar tienjarig bestaan. In het afgelopen decennium heeft de ERC bijgedragen aan vele wetenschappelijke projecten door heel Europa, waaronder op de Universiteit Leiden. De onderzoeksraad heeft bijna 7.000 onderzoekers gefinancierd, wat heeft geleid tot…

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Promotie

Promotie

Promotie

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Wrijving zet nuttige energie om in nutteloze warmte, en vermorst zo minstens 5 procent van alle welvaart in de wereld. Fysicus Joost Frenken wil wrijving tot vrijwel nul reduceren met nanostructuren op basis van grafeen. Dankzij een Advanced ERC Grant van 2,5 miljoen euro , kan hij dit onderzoek nu…

Op 21 juni sprak Jorrit Rijpma op de eerste bijeenkomst van het Task Force over een Europese Grens- en Kustwacht, opgericht door het Centre for European Policy Studies in Brussel.

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Van de negen Jong Talent Afstudeerprijzen gaan er vier naar Leidse alumni. Zij ontvangen de prijs op 29 november van de Koninklijke Hollandsche Maatschappij der Wetenschappen. Alle vier werken nu als promovendus in Leiden. De jury roemt hun innovatieve aanpak.

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

Promotie

Promotor: Prof.dr. G.J. Kroes

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.

Promotie

Lezing

Op vrijdag 25 mei is de oratie van Tjerk Oosterkamp over zijn leeropdracht 'Experimentele Natuurkunde'.

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.