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PhD student Chronic effects of advanced materials on organisms(0.8-1.0 fte)

Omvang (fte)
Geplaatst op
26 april 2022
5 mei 2022 Vacature gesloten

The Faculty of Science and Institute of Environmental Sciences (CML) are looking for:

PhD student Chronic effects of advanced materials on organisms(0.8-1.0 fte)
Vacancy number: 22-261

We are looking for an outstanding PhD candidate to work within the recently granted ERC-Consolidator project ‘EcoWizard’. The current hazard assessment toolbox is not well equipped with accurate approaches to assess the safety of engineered nanomaterials (ENMs) at the species level nor to assess the impacts of ENMs on species interactions. The EcoWizard project aims to acquire fundamental and generalizable insights into the chronic effects on species and species interactions induced by long-term exposure to (advanced) ENMs at environmentally relevant conditions. In this project we combine lab-based experiments with field-realistic experiments in tandem with ecophysiological and ecological modelling. The aim of this PhDproject is to relate fate processes of ENMs at realistic environmental exposure conditions to chronic ecophysiological underpinned responses. Research questions addressed are: can a process-based understanding on time dependent dissolution rates and aggregation be incorporated within dose-response models for species? Can ecophysiological traits of species aid to accurately understand response mechanisms at the exposure-bio interface allowing to optimize dose-response models for ENMs?

To address the EcoWizard aim, we formed a team with several PhD candidates and staff members who interact closely on adjacent research topics. The results of the EcoWizard project are likely to change the field of nanosafety as it fills key gaps in scientific knowledge, allowing for improved explanation of ecotoxicological effects after long-lasting exposure of the merit of different biological organisms.

Key tasks:
· Determine the nanomaterials-induced impacts on individual level (preferably to endpoints related to population level); making use of biomarkers and parameters related to the Dynamic Energy Budget theory (fat reserves, size, metabolism, feeding rate) and or uptake related ecophysiological parameters (overall surface, habitat/ type of feeding)
· Perform dose-response modelling and adding fate processes and mechanistic effect data enabling to accurately predict species sensitivity
· Conduct indoor and outdoor cosm experiments with organisms that are family and have distinct or comparable traits

Selection criteria
• You should have an M.Sc. in a relevant field (e.g. ecotoxicology, environmental science, and/or biology), but we also consider candidates from other scientific fields with good quantitative skills and an interest in studying human induced impacts to organisms and the biodiversity at large;
• Experimental and laboratory or field work skills are preferred
• Proficiency in spoken and written English and good communication skills
• Team player and having a collaborative attitude

Our organization
The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. The Institute of Environmental Sciences (CML) is positioned in the Faculty of Sciences. The core focus of CML is to perform research and education in the interdisciplinary field of Environmental Sciences. CML focuses on the sustainable use of natural resources and preservation of natural capital and biodiversity. CML has a culture of mutual support and collaboration between researchers. Presently, about 140 fte (including postdocs and PhDs) are employed at CML. CML has two departments: Industrial Ecology (CML-IE) and Environmental Biology (CML-EB). Within the Environmental Biology department we have an established and strong, international recognized ecotoxicology group led by Prof.dr. Vijver ( https://ecotox.science.leidenuniv.nl ) Within our group, we focus on the prediction and measurement of how existing and emerging chemical stressors affect our natural environment and organisms living there. We aim to provide essential tools to assess and mitigate ecosystem threats. Data collection for risk assessments takes place via different approaches, ranging from lab-derived experiments, to outdoor mesocosms (e.g in our Living Lab https://www.universiteitleiden.nl/levendlab), and field monitoring to process-based and spatially explicit modelling (e.g. using spatiotemporal data on pesticides = https://www.bestrijdingsmiddelenatlas.nl or site-specific metal risk assessments = https://pnec-pro.com ). Ultimately, the joint goal of these approaches is to understand chemically induced ecological impacts and link these to source emissions and/or actors. For more information, see https://www.science.leidenuniv.nl. Information about CML can be found at https://www.universiteitleiden.nl/en/science/environmental-sciences  

Terms and conditions 
We offer a 1-year position with the possibility of extension to 4 years based on performance. Salary ranges from € 2.443.- gross per month in the first year to € 3.122 gross per month in the fourth year based on a full-time position, in accordance with the Collective Labour Agreement for Dutch Universities. Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. For international spouses we have set up a dual career programme. Candidates from outside the Netherlands may be eligible for a substantial tax break.

Diversity and inclusion are core values of Leiden University. Leiden University is committed to becoming an inclusive community which enables all students and staff to feel valued and respected and to develop their full potential. Diversity in experiences and perspectives enriches our teaching and strengthens our research. High quality teaching and research is inclusive.

Enquiries can be made to Prof. Martina Vijver (vijver@cml.leidenuniv.nl)

To apply for this vacancy, please send an email to sollicitaties@cml.leidenuniv.nl. Please ensure that you upload the following additional documents quoting the vacancy number:
· CV
· A motivation letter (max 1 page)
Only applications received before May 5, 2022 will be considered. Interviews will take place in May 11, 2022. You are kindly requested to be available on this date.

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