Universiteit Leiden

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Tenure Track Assistant or Associate Professor

Wetenschappelijke functies
Omvang (fte)
Intern , Extern
Geplaatst op
6 april 2021
28 april 2021 Vacature gesloten

The Faculty of Science Leiden Academic Centre for Drug Research, and Leiden Institute of Chemistry are looking for a

Tenure Track Assistant or Associate Professor Computational Chemistry and Metabolic Networks

Project description
Metabolomics and chemical proteomics can measure biochemical network changes. These changes in biochemical networks due to disease or exposure to external factors can be measured in in-vitro models and advanced organ-on-a-chip models. A large amount of public and proprietary data has been generated in these areas. To couple in-vitro measurements to clinical data and pre-clinical data, advanced algorithms are needed to gain more information and knowledge from omics and mass-spectrometry based data, including quantification and identification/structure elucidation of metabolites and lipids. Exploring these data sources, connecting, and looking for breakthroughs on the border of chemistry, mass spectrometry, pharmaceutical sciences, and medicine is the ambition of this position.

Key responsibilities
The candidate will establish and maintain an independent research program within the Division of Systems Biomedicine and Pharmacology. Research is performed on the boundary of drug research and metabolomics. Candidates should have a background in chemistry and affinity with drug research. Candidates from the (broad) field of chemistry are invited to apply. Candidates aspire to excel in their discipline, and are open to collaborate within the institute with complementary disciplines, as well as other institutes within our faculty. Candidates are expected to contribute to the teaching programs of the Leiden Academic Centre for Drug Research, which include Bachelor and Master programs in Biopharmaceutical Sciences (BPS), as well as the Master program in Pharmacy. The position has a variety of tasks depending on the entry level assistant/associate professor:

  • Establish and maintain independent research lines in the field of computational chemistry and mass spectrometry and/or multiscale metabolic networks;
  • Collaborate with ongoing metabolomics, chemical proteomics and drug research lines in the context of the National Sectorplan Chemistry (LACDR and LIC);
  • Contribute to the development of a new generation of young academics;
  • Initiate ambitious research projects, write national and international grant proposals;
  • Teach at different levels of the curriculum and actively contribute to innovative teaching and to the translation of the research into teaching;
  • Undertake administrative, managerial and governance tasks within the Institute and Faculty;
  • Convey the academic knowledge and insights acquired to society.

Selection criteria

  • PhD degree in Chemistry or related disciplines;
  • Solid background with computational and experimental mass spectrometry;
  • Excellence in research, as proven by PhD thesis, publications, or other output;
  • Proven ability to obtain research grants;
  • Affinity to proven experience with teaching;
  • Leiden University requires teaching staff to obtain the University Teaching Qualification (UTQ).

Our organisation
The Leiden Academic Centre for Drug Research (LACDR) is a leading institute dedicated to world-class research and education in drug discovery and development. LACDR comprises a diverse and international team of approximately 150 researchers. The research conducted at the LACDR is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine & Pharmacology. The various research topics carried out within these themes are ideal for executing interdisciplinary research from, a strong monodisciplinary basis.

LACDR has key research applications in the area of drug research (small molecules and biologics) and computational research (artificial intelligence (AI) and mechanistic models). Research collaborations are in place between LACDR on one hand and the institutes of chemistry, biology, and the university medical center on the other. Key to the AI approaches is the recently inaugurated ALICE computer cluster at the university. Currently plans are formed for a second iteration that is set to more than double the calculation capacity. Moreover, at the LACDR researchers are running an internationally highly recognized research program on metabolomics comprising high throughput mass spectrometry-based technologies, computational metabolic modeling and artificial intelligence. In addition, in-vitro models, stem cell technologies and advanced imaging technologies are used for translational drug research (also in collaboration with the LUMC). Chemical proteomics strategies (LIC) are used for drug discovery, and innovative medicinal chemistry approaches to discover and develop compounds for several therapeutic areas. Leiden is part of several large key national programs (X-Omics, Exposome-NL) and international programs (eTRANSAFE, EU-ToxRisk) and data are integrated with in-vitro models and established knowledge; Leiden is leading several FAIR and open science initiatives to apply these to sophisticated AI approaches.

The Faculty of Science at Leiden University is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are committed to expand fundamental knowledge by curiosity and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future.

The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organized in eight institutes. These institutes offer eight bachelors’ and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 2,300 staff and over 5,000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

Terms and conditions
The assistant or associate professor starts with a temporary contract for a period of six years (tenure track) with the possibility of permanent employment based on good performance. 

The gross monthly salary at assistant professor level is between € 3.746,- and € 5.826,- (pay scale 11 or 12) and at associate professor level is between € 5.190,- and € 6.940,- (pay scale 13 or 14)depending on your level of experience. (in accordance with the Collective Labour Agreement for Dutch Universities). 

An appointment with Leiden University includes a pension build-up and other benefits; these include an annual holiday premium of 8%, an end-of-year premium of 8.3% and a paid parental leave of 62,5%. Candidates from outside the Netherlands may be eligible for a substantial tax break. For more information, see the website.

Dual Career Programme
Leiden University offers a Dual Career Programme (DCP) to assist the life partners of new academic staff (on pay-roll) in finding employment in The Netherlands. The programme is offered in close cooperation with nearby universities of Delft and Rotterdam (Erasmus). Candidates from outside the Netherlands may be eligible for a substantial tax break

Leiden University requires teaching staff to obtain the University Teaching Qualification (UTQ). For more information on the UTQ please go to our teacher qualification page on our website. Newly appointed staff is expected to obtain this qualification within 2-3 years from their appointment.

Tenure Track
Our Tenure track is expected to lead to a tenured position as associate professor and grow into the role of a full professor. With our Tenure track we offer you a clear and inviting career path to support you in the development of your personal and professional talents. It has a strong focus on coaching and training. A special mentor program is offered with fellow Tenure Trackers in a peer group, in order to develop your academic leadership skills.  You can read more about our Tenure Track on our website.

At the Faculty of Science we value inclusiveness and strive for a diverse community with equal opportunities for all. We give full support to our staff in achieving their potential to become independent academic researchers and teachers. For more information about our policy on diversity and equality please go to the diversity page on our website). Hence, Leiden University especially welcomes applications from members of underrepresented groups.

Enquiries about the position can be made to Prof. Thomas Hankemeier, email hankemeier@lacdr.leidenuniv.nl, Prof.  Mario van der Stelt, email m.van.der.stelt@chem.leidenuniv.nl or Prof. Gerard van Westen, email gerard@laccdr.leidenuniv.nl.

To apply for this vacancy, please send an e-mail to Cathy Robbers, email c.c.w.robbers@lacdr.leidenuniv.nl. The closing date is April 28th 2021. Please ensure that you include the following additional documents quoting the vacancy number:

  • Motivation letter;
  • Full curriculum vitae, including a list of publications;
  • Brief past and future research statements;
  • Contact details of at least three persons who can be contacted for reference.

Enquiries from agencies are not appreciated.

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