Universiteit Leiden

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Postdoctoral Researcher at the Faculty of Science and Institute of Biology

Wetenschappelijke functies
Omvang (fte)
Geplaatst op
28 mei 2019
28 juni 2019

Nog 9 dagen om te solliciteren

The Faculty of Science and Institute of Biology are looking for a

Postdoctoral researcher (1.0 FTE)

Key responsibilities
ne of the strategies developed by plants to survive stressful events is the ability to anticipate future stress by remembering a past stress experience, which requires the establishment of a so-called ´stress memory´. A memory of a past event may shape the response to future signals and may have significant effects on the survival and fitness of the organism. Currently, however, the molecular, biochemical and physiological mechanisms of stress memory are not well understood. Evidence from our lab indicates that the regulation of the in vivo stability of heat shock proteins (or chaperones in general) - and thus the ability to retain a good protein quality control system – represents an important cellular mechanism for establishing a memory about previous heat stress. Recently, we discovered the presence of a novel HSP21 – plastidial protease control module for heat stress memory (thermomemory) in plants (Sedaghatmehr et al., 2016, Nature Commun). Moreover, we discovered autophagy as another intracellular protein quality control system involved in the regulation of thermomemory in Arabidopsis thaliana (Sedaghatmehr et al., 2018, Plan Cell Environ).

The successful candidate will follow-up ongoing projects with a focus on investigating the selective role of autophagy in the regulation of heat stress and thermomemory in Arabidopsis and tomato. Your key tasks include:

  • Plan and conduct research activities;
  • Co-supervise PhD and graduate students;
  • Write manuscripts for publication of significant research results;
  • Write grant applications.

Selection criteria

  • You have in-depth knowledge of cell and molecular biology;
  • You have hands-on experience in transcriptome profiling, DNA-protein and protein-protein interaction analysis, immunoblotting, protein purification and confocal microscopy.
  • You must be proficient in spoken and written English and have good communication skills;
  • You are a team player, but also able to work independently;
  • You take initiative and have a strong interest in academic research;
  • You have good organizational skills;
  • You are capable of presenting data at meetings and conferences.

Research at our Faculty
The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are driven by curiosity to expand fundamental knowledge and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future.

The research carried out at the Faculty is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organised in eight institutes. These institutes offer eight bachelor’s and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 1,300 staff and almost 4,000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

The Institute of Biology (IBL) is positioned in the Faculty of Sciences. The core business of IBL is to perform top quality innovative fundamental and strategic research that will lead to scientific progress, contribute to solutions for societal challenges, and generate industrial opportunities. The Institute is organised in three multidisciplinary clusters: Animal Sciences & Health, Plant Sciences & Natural Products and Microbial Biotechnology & Health. Presently, over 120 fte (including postdocs and PhDs) are employed at IBL.

Terms and conditions
We offer a three-year position. The salary range is from €2.709 to €4.272 gross per month (pay scale 10 in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. For international spouses we have set up a dual career programme. Candidates from outside the Netherlands may be eligible for a substantial tax break. More at: https://www.universiteitleiden.nl/en/working-at/job-application-procedure-and-employment-conditions.

Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

For more information about the IBL, please visit https://www.universiteitleiden.nl/en/science/biology. Enquiries can be made to dr. Salma Balazadeh, e-mail: sylvius@biology.leidenuniv.nl.

To apply for this vacancy, please send an e-mail to sylvius@biology.leidenuniv.nl with a motivation letter, cv and the names and phone numbers of two referees, no later than 28th of June 2019. However, the call for the position will remain open until a suitable candidate is found.

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