Wanda van der Stel
Onderzoeker
- Naam
- Dr. W. van der Stel
- Telefoon
- +31 71 527 6039
- w.van.der.stel@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0001-8289-7189
Voor meer informatie zie Engelse profielpagina.
Onderzoeker
- Wiskunde en Natuurwetenschappen
- Leiden Academic Centre for Drug Research
- LACDR/Toxicology
- Noord V.E. van der, Stel W. van der, Louwerens G., Verhoeven D., Kuiken H.J., Lieftink C., Grandits M., Ecker G.F., Beijersbergen R.L., Bouwman R.J.P., Le Dévédec S.E. & Water B. van de (2023), Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors, Breast Cancer Research 25(1): 51.
- Liu Q., Liu N.S., Noord V.E. van der, Stel W. van der, Water B. van de, Danen E.H.J. & Le Dévédec S.E. (2023), Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia, Breast Cancer Research and Treatment 198: 583-596.
- Liu Q., Stel W. van der, Noord V.E. van der, Leegwater H., Coban B., Elbertse K., Pruijs J.T.M., Béquignon O.J.M., Westen G.J.P. van, Dévédec S.E. le & Danen E.H.J. (2022), Hypoxia triggers TAZ phosphorylation in basal a triple negative breast cancer cells, International Journal of Molecular Sciences 23(17): 10119.
- Tebby C., Gao W., Delp J., Carta G., Stel W. van der, Leist M., Jennings P., Water B. van de & Bois F.Y. (2022), A quantitative AOP of mitochondrial toxicity based on data from three cell lines, Toxicology In Vitro 81: 105345.
- Duijndam B.H.A., Tedeschi M., Stel W. van der, Hoorn T. van den, Burg B. van der, Bouwman R.J.P., Laan J.W. van der & Water B. van der (2022), Evaluation of an imaging-based in vitro screening platform for estrogenic activity with OECD reference chemicals, Toxicology In Vitro 81: 105348.
- Stel W. van der, Yang H., Le Dévédec S.E., Water B. van de, Beltman J.B. & Danen E.H.J. (2023), High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for oxphos complex I, III, and V inhibitors, Cell Biology and Toxicology 39: 415-433.
- Stel W. van der (1 februari 2022), Mitochondria in chemical-induced toxicity (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Faculty of Science, Leiden University). Promotor(en): Danen E.H.J. & Water B. van de.
- Stel W. van der, Yang H., Vrijenhoek N.G., Schimming J.P., Callegaro G., Carta G., Darici S., Delp J., Forsby A., White A., Le Dévédec S.E., Leist M., Jennings P., Beltman J.B., Water B. van de & Danen E.H.J. (2022), Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation, Archives of Toxicology 96: 259-285.
- Yang H., Stel W. van der, Lee R., Bauch C., Bevan S., Walker P., Water B. van de, Danen E.H.J. & Beltman J.B. (2021), Dynamic modeling of mitochondrial membrane potential upon exposure to mitochondrial inhibitors, Frontiers in Pharmacology 12.
- Stel W. van der, Carta G., Eakins J., Delp J., Suciu I., Forsby A., Cediel-Ulloa A., Attoff K., Troger F., Kamp H., Gardner I., Zdrazil B., Moné1 M.J., Ecker G.F., Pastor M., Gómez-Tamayo J.C., White A., Danen E.H.J., Leist M., Walker P., Jennings P., Hougaard Bennekou S. & Water B. van de (2021), New approach methods supporting read-across: two neurotoxicity AOP-based IATA case studies, ALTEX : Alternatives to Animal Experimentation 38(4): 615-635.
- Duijndam B., Goudriaan A., Hoorn T. van den, Stel W. van der, Le Dévédec S.E., Bouwman R.J.P., Laan J.W. van der & Water B. van de (2021), Physiologically relevant estrogen receptor alpha pathway reporters for single-cell imaging-based carcinogenic hazard assessment of estrogenic compounds, Toxicological Sciences 181(2): 187-198.
- Delp J., Cediel-Ulloa A., Cuciu I., Kranaster P., Vugt-Lussenburg B.M.A. van, Munic Kos V., Stel W. van der, Carta G., Hougaard Bennekou S., Jennings P., Water B. van de, Forsby A. & Leist M. (2021), Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors, Archives of Toxicology 95: 591-615.
- Stel W. van der Carta G. Eakins J. Darici S. Delp J. Forsby A. Bennekou S.H. Gardner I. Leist M. Danen E.H.J. Walker P. Water B. van de Jennings P. (2020), Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals, Archives of Toxicology 94(8): 2707-2729.
- Troger F., Delp F.J., Funke M., Stel W. van der, Colas C., Leist M., Water B. van de & Ecker G.F. (2020), Identification of mitochondrial toxicants by combined in silico and in vitro studies : a structure-based view on the adverse outcome pathway, Computational Toxicology 14.
- Delp J., Funke M., Rudolf F., Cediel A., Hougaard Bennekou S., Stel W. van der, Carta G., Jennings P., Toma C., Gardner I., Water B. van de, Forsby A. & Leist M. (2019), Development of a neurotoxicity assay that is tuned to detect mitochondrial toxicants, Archives of Toxicology 93(6): 1585-1608.
- Stel W. van der, Darici S., Water B. van de & Danen E. (2018), Unravelling essential key events in mitochondrial adverse outcome pathways, Toxicology Letters 295: S193-S194.
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