Universiteit Leiden

nl en

Johan Lugtenburg

Emeritus hoogleraar Organische chemie in het bijzonder de bio-organische fotochemie

Naam
Prof.dr. J. Lugtenburg
Telefoon
+31 71 527 4405
E-mail
lugtenbu@chem.leidenuniv.nl

Emeritus hoogleraar Organische chemie in het bijzonder de bio-organische fotochemie

  • Wiskunde en Natuurwetenschappen
  • Leiden Institute of Chemistry
  • LIC/Bio-organic Synthesis

Werkadres

Gorlaeus Laboratoria
Einsteinweg 55
2333 CC Leiden
Kamernummer DM4.24

Contact

  • Bovee-Geurts P.H.M., Lugtenburg J. & Grip W.J. de (2017), Coupled HOOP signature correlates with quantum yield of isorhodopsin and analog pigments, BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1858: 118-125.artikel in tijdschrift (refereed)
  • Wisse P., Gold H., Mirzaian M., Ferraz M.J., Lutteke G., Berg R.J.B.H.N. van den, Elst H. van den, Lugtenburg J., Marel G.A. van der, Aerts J.M.F.G., Codee J.D.C. & Overkleeft H.S. (2015), Synthesis of a Panel of Carbon-13-Labelled (Glyco)Sphingolipids, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (12): 2661-2677.artikel in tijdschrift (refereed)
  • Ganapathy S., Becheau O., Venselaar H., Frolich S., Steen J.B. van der, Chen Q., Radwan S., Lugtenburg J., Hellingwerf K.J., Groot H.J.M. de & Grip W.J. de (2015), Modulation of spectral properties and pump activity of proteorhodopsins by retinal analogues, BIOCHEMICAL JOURNAL 467: 333-343.artikel in tijdschrift (refereed)
  • Yi A., Ogren J.I., Mamaev S., Li H., Lugtenburg J., Grip W.J. de, Spudich J.L. & Rothschild K.J. (2015), Vibrational Studies of Channelrhodopsin-1 from Chlamydomonas Augustae: Protonation Changes during the Early Photocycle. [overig]overig
  • Ogren J.I., Yi A., Mamaev S., Li H., Lugtenburg J., Grip W.J. de, Spudich J.L. & Rothschild K.J. (2015), Comparison of the Structural Changes Occurring during the Primary Phototransition of Two Different Channelrhodopsins from Chlamydomonas Algae, BIOCHEMISTRY 54(2): 377-388.artikel in tijdschrift (refereed)
  • Samoilova Rimma I., Taguchi Alexander T., O'Malley Patrick J., Dikanov Sergei A. & Lugtenburg Johan (2014), Hyperfine Interaction Tensors of C-13 Nuclei for Ring Carbons of Ubisemiquinone-10 Hydrogen Bonded in Alcohol Solvents, APPLIED MAGNETIC RESONANCE 45(9): 941-953.artikel in tijdschrift (refereed)
  • Talab Sarra, Taha Kamal Khalifa & Lugtenburg Johan (2014), Preparation of 2 '-C-13-L-Histidine Starting from C-13-Thiocyanate: Synthetic Access to Any Site-Directed Stable Isotope Enriched L-Histidine, MOLECULES 19(1): 1023-1033.artikel in tijdschrift (refereed)
  • Gold H., Mirzaian M., Dekker N., Joao Ferraz M., Lugtenburg J., Codee J.D.C., Marel G.A. van der, Overkleeft H.S., Linthorst G.E., Groener J.E.M., Aerts J.M.F.G. & Poorthuis B.J.H.M. (2013), Quantification of Globotriaosylsphingosine in Plasma and Urine of Fabry Patients by Stable Isotope Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry, Clinical Chemistry 59(3): 547-556.artikel in tijdschrift (refereed)
  • Gold H., Mirzaian M., Dekker N., Joao Ferraz M., Lugtenburg J., Codee J.D., van der Marel G.A., Overkleeft H.S., Linthorst G.E., Groener J.E., Aerts J.M. & Poorthuis B.J. (2012), Quantification of Globotriaosylsphingosine in Plasma and Urine of Fabry Patients by Stable Isotope Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry, Clinical Chemistry.artikel in tijdschrift (refereed)
  • DeGrip W.J., Bovee-Geurts P.H., Wang Y., Verhoeven M.A. & Lugtenburg J. (2011), Cyclopropyl and isopropyl derivatives of 11-cis and 9-cis retinals at C-9 and C-13: subtle steric differences with major effects on ligand efficacy in rhodopsin, Journal of Natural Products 74(3).artikel in tijdschrift (refereed)
  • Mathies G., Hemert M.C. van, Gast P., Sai Sankar Gupta K.B., Frank H.A., Lugtenburg J. & Groenen E.J.J. (2011), Configuration of Spheroidene in the Photosynthetic Reaction Center of Rodobacter sphaeroides: A Comparison of Wild-Type and Reconstituted R26, Journal of Physical Chemistry A 115(34): 9552-9556.artikel in tijdschrift (refereed)
  • Daviso E., Diller A., Gast P., Alia A, Lugtenburg J., Müller M.G. & Matysik J. (2010), Action spectroscopy on dense samples of photosynthetic reaction centers of Rhodobacter sphaeroides WT based on nanosecond laser-flash C-13 Photo-CIDNP MAS NMR, Applied Magnetic Resonance 38: 105-116.artikel in tijdschrift (refereed)
  • Gansmuller Axel, Concistre Maria, McLean Neville, Johannessen Ole G., Marin-Montesinos Ildefonso, Bovee-Geurts Petra H. M., Verdegem Peter, Lugtenburg Johan, Brown Richard C. D., DeGrip Willem J. & Levitt Malcolm H. (2009), Towards an interpretation of C-13 chemical shifts in bathorhodopsin, a functional intermediate of a G-protein coupled receptor, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1788(6): 1350-1357.artikel in tijdschrift (refereed)
  • Bovee-Geurts P., Fernandez Fernandez I., Liu R. S., Mathies R. A., Lugtenburg J. & DeGrip W. J. (2009), Fluoro derivatives of retinal illuminate the decisive role of the C(12)-H element in photoisomerization and rhodopsin activation, J Am Chem Soc 131(49): 17933-42.artikel in tijdschrift (refereed)
  • Abello N., Geurink P.P., Toorn M. van den, Oosterhout A.J.M. van, Lugtenburg J., Marel G.A. van der, Kerstjens H.A.M., Postma D.S., Overkleeft H.S. & Bischoff R. (2008), Poly(ethylene glycol)-Based Stable Isotope Labeling Reagents for the Quantitative Analysis of Low Molecular Weight Metabolites by LC-MS, Analytical Chemistry 80: 9171-9180.artikel in tijdschrift (refereed)
  • Wang Y., Bovee-Geurts P.H., Lugtenburg J. & DeGrip W.J. (2008), Alpha-retinals as rhodopsin chromophores - Preference for the 9-Z configuration and partial agonist activity, Photochemistry and Photobiology 84(4): 889-894.artikel in tijdschrift (refereed)
  • Concistre M., Gansmüller A., McLean N., Johannessen O.G., Marín Montesinos I., Bovee-Geurts P.H.M., Verdegem P, Lugtenburg J., Brown R.C.D., DeGrip W.J. & Levitt M.H. (2008), Double-quantum C-13 nuclear magnetic resonance of bathorhodopsin, the first photointermediate in mammalian vision, Journal of the American Chemical Society 130(32): 10490.artikel in tijdschrift (refereed)
  • Concistre M., Gansmuller A., McLean N., Johannessen O.G., Montesinos I.M.,; Bovee-Geurts P.H.M., Verdegem P., Lugtenburg J., Brown R.C.D. DeGrip W.J. & Levitt M.H. (2008), Double-quantum (13)C nuclear magnetic resonance of bathorhodopsin, the first photointermediate in mammalian vision, Journal of the American Chemical Society .artikel in tijdschrift (refereed)
  • DeGrip Willem J., Bovee-Geurts Petra H. M., van der Hoef Ineke & Lugtenburg Johan (2007), 7,8-dihydro retinals outperform the native retinals in conferring photosensitivity to visual opsin, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 129(43): 13265-13269.artikel in tijdschrift (refereed)
  • Rossum B.J. van, Liemt W.B.S. van, Gast P., Lugtenburg J. & Groot H.J.M. de (2007), C-13-H-1 heteronuclear dipolar correlation studies of the hydrogen bonding of the quinones in Rhodobacter sphaeroides R26 reaction centers, Applied Magnetic Resonance 31: 145-158.artikel in tijdschrift (refereed)
  • Wirtz A.C., Hemert M.C. van, Lugtenburg J., Frank H.A. & Groenen E.J.J. (2007), Two stereoisomers of Spheroidene in the Rhodobacter sphaeroides R26 reaction center: A DFT analysis of Resonance Raman spectra, Biophysical Journal 93: 981-991.artikel in tijdschrift (refereed)
  • Rossum B.J. van, Liemt W.B.S. van, Gast P., Lugtenburg J. & Groot H.J.M. de (2007), 13C-1H Heteronuclear Dipolar Correlation Studies of the Hydrogen bonding of the Quinones in Rhodobacter sphaeroides R26 RCs, Applied Magnetic Resonance 31: 145-158.artikel in tijdschrift (refereed)
  • Lai W.C., McLean N., Gansmüller A., Verhoeven M.A., Antonioli G.C., Carravetta M., Duma L., Bovee-Geurts P.H.M., Johanessen O.G., Groot H.J.M. de, Lugtenburg J., Emsley L., Brown S.P., Brown R.C.D., DeGrip W.J. & Levitt M.H. (2006), Accurate measurements of 13C-13C J-couplings in the rhodopsin chromophore by double quantum solid state NMR spectroscopy, Journal of the American Chemical Society 128: 3878-3879.artikel in tijdschrift (refereed)
  • Pendon Z.D., Hoef I. van der, Lugtenburg J. & Frank H.A. (2006), Triplet state spectra and dynamics of geometric isomers of carotenoids, Photosynthesis Research 88: 51-61.artikel in tijdschrift (refereed)
  • Verhoeven M.A., Bovee-Geurts P.H.M., Groot H.J.M. de, Lugtenburg J. & Grip W.J. de (2006), Methyl substituents at the 11 or 12 position of retinal profoundly and differentially affect photochemistry and signalling activity of rhodopsin, Journal of Molecular Biology 363: 98-113.artikel in tijdschrift (refereed)
  • Wijk A.A.C. van, Spaans A.P., Uzunbajakava N., Otto C., Groot H.J.M. de, Lugtenburg J. & Buda F. (2005), Spectroscopy and quantum chemical modelling reveal a predominant contribution of excitonic interactions to the bathochromatic shift in alpha-crustacyanin, the blue carotenoprotein in the carapace of the lobster Homarus gammarus, Journal of the American Chemical Society 127: 1438-1445.artikel in tijdschrift
  • Kiihne S.R., Creemers A.F.L., Grip W.J. de, Bovee-Geurts P.H.M., Lugtenburg J. & Groot H.J.M. de (2005), Selective interface detection: mapping binding site contact in membrane proteins by NMR-spectroscopy, Journal of the American Chemical Society 127: 5734-5735.artikel in tijdschrift
  • Lorenzo A.-G., Pazos Y., Navarro-Vázquez A., Lugtenburg J. & Cid M. (2005), Preparation of 13C4-6-methyl anthrallic ester via a Diels Alder type process. An experimental and theoretical study to characterize an unexpected isotope exchange, Organical Letters 7: 3773-3776.artikel in tijdschrift
  • Haas R.N.S. van der, Tang S.-H., Arenas Hernández B., Jong R.L.P. de, Erkelens C., Liu Y., Gast P., Smijs T.G., Schuitmaker H. & Lugtenburg J. (2005), Synthesis of the dimethyl ester of 2'-cyano-8'-formyl-N'-methyl-1',1a',5a',6'-tetrahydroacrido[4,5,5a,6-bcd]-annulated 2,3-dihydromesoporphyrin ¿ A novel system with outstanding properties as basis for photodynamic therapy in the far-red region if the visible spectrum, European Journal of Organic Chemistry: 3813-3824.artikel in tijdschrift
  • Pendon Z.D., Sullivan J.O., Hoef I., Lugtenburg J., Cua A., Bocian D.F., Birge R.R. & Frank H.A. (2005), Stereoisomers of carotenoids: spectroscopic properties of locked and unlocked cis-isomers of spheroidene, Photosynthesis Research 86: 5-24.artikel in tijdschrift
  • Pendon Z.D., Gibson G.N., Hoef I. van der, Lugtenburg J. & Frank H.A. (2005), Effect of isomer geometry on the steady-state absorption spectra and femtosecond time-resolved dynamics of carotenoids, Journal of Physical Chemistry B 109: 21172-21179.artikel in tijdschrift
  • Haas R.N.S. van der, Tang S.-H., Hernandez B.A., Jong R.L.P. de, Erkelens C., Liu Y., Gast P., Smijs T.G., Schuitmaker H.J. & Lugtenburg J. (2005), Synthesis of the dimethyl ester of 2-cyano-8-formyl-N-methyl-1,1a,5a,6-tetrahydroacrido [4.5,5a,6-bcd]-annulated 2,3-dihydromesoporphyrin A novel system with outstanding properties as basis forphotodynamic therapy in the far-red region of the visible spectrum., European Journal of Organic Chemistry 17: 3818-3824.artikel in tijdschrift (refereed)
  • Creemers AFL, Bovee-Geurts PHM, DeGrip WJ, Lugtenburg J & de Groot HJM (2004), Solid-state NMR analysis of ligand-receptor interactions reveals an induced misfit in the binding site of isorhodopsin, BIOCHEMISTRY 43(51): 16011-16018.artikel in tijdschrift (refereed)
  • Wang YJ, Bovee-Geurts PHM, Lugtenburg J & DeGrip WJ (2004), Constraints of the 9-methyl group binding pocket of the rhodopsin chromophore probed by 9-halogeno substitution, BIOCHEMISTRY 43(46): 14802-14810.artikel in tijdschrift (refereed)
  • Spooner PJR, Sharples JM, Goodall SC, Bovee-Geurts PHM, Verhoeven MA, Lugtenburg J, Pistorius AMA, DeGrip WJ & Watts A (2004), The ring of the rhodopsin chromophore in a hydrophobic activation switch within the binding pocket, JOURNAL OF MOLECULAR BIOLOGY 343(3): 719-730.artikel in tijdschrift (refereed)
  • Carravetta M, Zhao X, Johannessen OG, Lai WC, Verhoeven MA, Bovee-Geurts PHM, Verdegem PJE, Kiihne S, Luthman H, de Groot HJM, deGrip WJ, Lugtenburg J & Levitt MH (2004), Protein-induced bonding perturbation of the rhodopsin chromophore detected by double-quantum solid-state NMR, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 126(12): 3948-3953.artikel in tijdschrift (refereed)
  • Nieboer M., Vroom E. de, Lugtenburg J., Schipper D., Vollebregt A.W.H. & Bovenberg R.A.L. (2003), Process for the fermentative production of deacylated cephalosporins ( octrooi nr. US 6,518,039 B2). [octrooi]octrooi
  • Wijk A.A.C. van, Weerd MB van de & Lugtenburg J. (2003), Synthetic Scheme for the Preparation of 13C-Labeled 3,4-Didehydro-Retinal, 3-Hydroxyretinal, and 4-Hydroxyretinal up to Uniform 13C-Enrichment, European Journal of Organic Chemistry: 863-868.artikel in tijdschrift (refereed)
  • Alia Alia, Hulsebosch B., Gorkom H.J. van, Raap J., Lugtenburg J., Matysik J., Groot H.J.M. de & Gast P. (2003), Probing the electronic structure of tyrosine radial Y-D (center dot) in photosystem II by EPR spectroscopy using site specific isotope labelling in Spirodela oligorrhiza, Chemical Physics 294: 459-469.artikel in tijdschrift (refereed)
  • Bade Shrestha-Dawadi P. & Lugtenburg J. (2003), Preparation of [1,2,3,4,5-13C5]-amino-4-oxopentanoic acid (ALA) - Design of a synthetic scheme to prepare 13C- and 15N-isotopomer with high isotopic enrichment, European Journal of Organic Chemistry: 4654-4663.artikel in tijdschrift (refereed)
  • Kelemen P., Lugtenburg J. & Mumperman B. (2003), N-15 NMR spectroscopy of labeled alkoxyamines. N-15 labeled model compounds for nitroxide-trapping studies in free-radical (Co)polymerization, Journal of Organic Chemistry 68: 7322-7328.artikel in tijdschrift (refereed)
  • Lieshout M., West C.E., Bovenkamp P. van de, Wang Y., Sun Y.K., Breemen R.B., Muhilal D.P., Verhoeven M.A., Creemers A.F.L. & Lugtenburg J. (2003), Extraction of carotenoids from feces, enabling the bioavailability of beta-carotene to be studied in Indonesian children, Journal of Agricultural and Food Chemistry 51: 5123-5130.artikel in tijdschrift (refereed)
  • Remy A., Boers R.B., Egorova-Zachernyuk T.A., Gast P., Lugtenburg J. & Gerwert K. (2003), Does different orientation of the methoxy groups of ubiquinone- 10 in the reaction centre of Rhodobacter sphaeroides cause different binding at Q(A) and Q(B)?, European Journal of Biochemistry 270: 3603-3609.artikel in tijdschrift (refereed)
  • Siebum A.H.G., Woo W.S. & Lugtenburg J. (2003), Preparation and characterization of [5-13C]-(2S,4R)-leucine and [4-13C]-(2S,3S)-valine - Establishing synthetic schemes to prepare any site-directed isotopomer of L-isoleucine and L-valine, European Journal of Organic Chemistry: 4664-4678.artikel in tijdschrift (refereed)
  • Spooner P.J.R., Sharples J.M., Goodall S.C., Seedorf H., Verhoeven M.A., Lugtenburg J., Bovee-Geurts P.H.M., Grip W.J. de & Watts A. (2003), Conformational similarities in the beta-ionone ring region of the rhodopsin chromophore in its ground state and after photoactivation to the metarhodopsin-1 intermediate, Biochemistry 42: 13371-13378.artikel in tijdschrift (refereed)
  • Wijk A.A.C. van, Weerd MB van de & Lugtenburg J. (2003), Synthetic scheme for the preparation of C-13-labeled 3,4-didehydro-retinal, 3-hydroxyretinal, and 4-hydroxyretinal up to uniform C-13-enrichment, European Journal of Organic Chemistry: 863-868.artikel in tijdschrift (refereed)
  • Alia Alia, Hulsebosch B., Gorkom H.J. van, Raap J., Lugtenburg J. & Matysik J. (2003), Probing the electronic structure of tyrosine radical Yd. in photosystem II by EPR spectroscopy using site specific isotope labeling in Spirodela, Chemical Physics 294: 459-469.artikel in tijdschrift (refereed)
  • Remy A., Boers R.B., Egorova-Zachernyuk T.A., Gast P., Lugtenburg J. & Gerwert K. (2003), Does different orientation of the methoxy groups of ubiquinone-10 in the reaction centre of Rhodobacter sphaeroides cause different binding at QA and QB?, European Journal of Biochemistry 270: 3603-3609.artikel in tijdschrift (refereed)
  • Nieboer M., Vroom E. de, Lugtenburg J., Schipper D., Vollebregt A.W.H. & Bovenberg R.A.L. (2002), process for the fermentative production of deacylated cephalosporins ( octrooi nr. US 6, 410,259 B1). [octrooi]octrooi
  • Boers R.B., Gast P., Hoff A.J., Groot H.J.M. de & Lugtenburg J. (2002), Synthesis and Spectroscopic Characterization of 5-13C and 6-13C- Ubiquinone-10 for Studies of Bacterial Photosynthetic Reaction Centers, European Journal of Organic Chemistry: 189-202.artikel in tijdschrift (refereed)
  • Lansing J.C., Hohwy M., Jaroniec CP, Creemers A.F.L., Lugtenburg J., Herzfeld J. & Griffin R.G. (2002), Chromophore distortions in the bacteriorhodopsin photocycle: evolution of the H-C14-C15-H digedral angle measured by solid state NMR, Biochemistry 41: 431-438.artikel in tijdschrift (refereed)
  • Frank H.A., Josue JS, Bautista J.A., Hoef K. van der, Jansen F.J.H.M., Lugtenburg J., Wiederrecht G & Christensen R.L. (2002), Spectroscopic and photochemical properties of open-chain carotenoids, Journal of Physical Chemistry 106: 2083-2092.artikel in tijdschrift (refereed)
  • Winters R., Heinen W., Verbruggen M.A.L., Lugtenburg J., Duin M. van & Groot H.J.M. de (2002), Solid State 13C NMR Study of Accelerated-Sulfur-Vulcanized 13C Labeled ENB-EPDM, Macromolecules 35(5): 1958-1966.artikel in tijdschrift (refereed)
  • Creemers A.F.L., Kiihne S.R., Bovee-Geurts P., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (2002), 1H and 13C MAS NMR Evidence for Pronounced Ligand-Protein Interactions Involving the Ionone Ring of the Retinylidene Chromophore in Rhodopsin, Proceedings of the National Academy of Science of the United States of America 99: 9101-9106.artikel in tijdschrift (refereed)
  • Schulten E.A.M., Matysik J., Raap J., Lugtenburg J., Gast P., Hoff A.J. & Groot H.J.M. de (2002), 13C MAS NMR and Photo-CIDNP Reveal a Pronounced Assumetrie in the Electron Ground State of the Special Pair of Rhodobacter Spearoides Reaction Centers, Biochemistry 41: 8708-8717.artikel in tijdschrift (refereed)
  • Boers R.B., Gast P., Hoff A.J., Groot H.J.M. de & Lugtenburg J. (2002), Synthesis and Spectroscopic Characterization of (5-13C) - and (6-13C) - Ubiquinone-10 for Studies of Bacterial Photosynthetic Reaction Centers, European Journal of Organic Chemistry: 189-202.artikel in tijdschrift (refereed)
  • Ouwerkerk N., Steenweg M., Ruijter M. de, Brouwer J., Boom J.H. van, Lugtenburg J. & Raap J. (2002), One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides, Journal of Organic Chemistry 67: 1480-1489.artikel in tijdschrift (refereed)
  • Petkova A.T., Hatanaka M., Jaroniec CP, Jingui G.H., Belenky M., Verhoeven M.A., Lugtenburg J. & Herzfeld J. (2002), Tryptophan interactions in bacteriorhodopsin: A heteronuclear solid state NMR study, Biochemistry 41: 2429-2437.artikel in tijdschrift (refereed)
  • Maeda A., Balashov S., Lugtenburg J., Verhoeven M.A., Herzfeld J., Belenky M., Gennis R.B., Tomson F.L. & Ebrey T.G. (2002), Interaction of internal water molecules with the Schiff base in the L-intermediate of the bacteriorhodopsin photocycle, Biochemistry 41: 3803-3809.artikel in tijdschrift (refereed)
  • Mukai-Kuroda Y., Fujii R., Ko-chi N., Sashima T., Koyama Y., Abe M., Gebhard R., Hoef K. van der & Lugtenburg J. (2002), Changes in molecular structure upon triplet excitation of all-trans spheroidene in n-hexane solution and 15-cis-spheroidene bound to the photoreaction center from rhodobacter sphaeroides as revealed by resonance Raman spectroscopy and normal coordinate analysis, Journal of Physical Chemistry A 106: 3566-3579.artikel in tijdschrift (refereed)
  • Pan D., Ganim Z., Kim J.E., Verhoeven M.A., Lugtenburg J. & Mathies R.A. (2002), Time-resolved resonance Raman analysis of chromphore structural changes in the formation and decay of rhodopsin's BSI intermediate, Journal of the American Chemical Society 124: 4857-4864.artikel in tijdschrift (refereed)
  • Creemers A.F.L. & Lugtenburg J. (2002), The preparation of all-trans uniformly 13C-labeled retinal via a modular total organic synthetic strategy. Emerging central contribution of organic synthesis toward the structure and function study with atomic resolution in protein research, Journal of the American Chemical Society 124: 6324-6334.artikel in tijdschrift (refereed)
  • Boers R.B., Pazos Randulfe Y., Haas H.N.S. van der, Rossum-Baan M van & Lugtenburg J. (2002), Synthesis and spectroscopic characterization of 1-13C- and 4-13C-plastoquinone-9, European Journal of Organic Chemistry: 2094-2108.artikel in tijdschrift (refereed)
  • Spooner P.J.R., Sharples J.M., Verhoeven M.A., Lugtenburg J., Glaubitz C. & Watts A. (2002), Relative orientation between the beta-ionone ring and the polyene chain for the chromophore of rhodopsin in native members, Biochemistry 41: 7549-7555.artikel in tijdschrift (refereed)
  • Ouwerkerk N., Boom J.H. van, Lugtenburg J. & Raap J. (2002), Synthesis of [1',2',5',2-13C4]-2'-deoxy-D-adenosine by a chemoenzymatic strategy to enable labelling of any of the 215 carbon-13 and nitrogen-15 isotopomers, European Journal of Organic Chemistry: 2356-2362.artikel in tijdschrift (refereed)
  • Hatcher M.E., Hu J.G., Belenky M., Verdegem P.J.E., Lugtenburg J., Griffin R.G. & Herzfeld J. (2002), Control of the pump cycle in bacteriorhodopsin: mechanisms elucidated by solid state NMR of the D85N mutant, Biophysical Journal 82: 1017-1029.artikel in tijdschrift (refereed)
  • Klei S.A. van der, Jong R.L.P. de, Lugtenburg J. & Tielens A.G.G.M. (2002), Synthesis and spectroscopic characterization of [1'-14C]ubiquinone-2, [1'-14C]-5-demethoxy-5-hydroxyubiquinone-2, and [1'-14C]-5-demethoxyubiquinone-2, European Journal of Organic Chemistry: 3015-3023.artikel in tijdschrift (refereed)
  • Dokter A.M., Hemert M.C. van, Velt C.M. in 't, Hoef K. van der, Lugtenburg J., Frank H.A. & Groenen E.J.J. (2002), Resonance Raman spectrum of all-trans sphaeroidene. DFT analysis and isotope labeling, Journal of Physical Chemistry A 106: 9463-9469.artikel in tijdschrift (refereed)
  • Wijk A.A.C. van & Lugtenburg J. (2002), Synthetic scheme for the preparation of 13C-labeled 2,7-dimethyllocta-2,4,6-triene-1,8-dial, the central part of carotenoids, European Journal of Organic Chemistry: 4217-4221.artikel in tijdschrift (refereed)
  • Dokter A.M., Hemert M.C. van, Velt C.M. in 't, Hoef K. van der, Lugtenburg J., Frank H.A. & Groenen E.J.J. (2002), The resonance Raman spectrum of all-trans spheroidene. DFT analysis and isotope labeling, Journal of Physical Chemistry A 106(41): 9463-9469.artikel in tijdschrift (refereed)
  • Boers R.B., Gast P., Hoff A.J., Groot H.J.M. de & Lugtenburg J. (2002), Synthesis and spectroscopic characterization of (5-C-13)- and (6-C-13)-ubiquinone-10 for studies of bacterial photosynthetic reaction centers, European Journal of Organic Chemistry 1: 189-202.artikel in tijdschrift (refereed)
  • Schulten E.A.M., Matysik J., Alia A, Kiihne S.R., Raap J., Lugtenburg J., Gast P., Hoff A.J. & Groot H.J.M. de (2002), C MAS NMR and Photo-CIDNP Reveal a Pronounced Asymmetry in the Electronic Ground State of the Special Pair of Rhodobacter sphaeroides Reaction Centers, Biochemistry 41: 8708-8717.artikel in tijdschrift (refereed)
  • Verdegem P.J.E., Monnee M.C.F. & Lugtenburg J. (2001), Simple and Efficient Preparation of [10,20-13C2]- and [10-CH3,13-13C2]-10-Methylretinal: Introduction of Substituents at the 2-Position of 2,3-Unsaturated Nitriles, Journal of Organic Chemistry 66: 1269-1282.artikel in tijdschrift (refereed)
  • Verhoeven M.A., Creemers A.F.L., Bovee-Geurts P.H.M., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (2001), Ultra-High-Field MAS NMR Assay of a Multispin Labeled Ligand Bound to Its G-Protein Receptor Target in the Natural Membrane Environment: Electronic Structure of the Retinylidene Chromophore in Rhodopsin, Biochemistry 40: 3282-3288.artikel in tijdschrift (refereed)
  • Kandori H., Yamazaki Y., Shichida Y, Raap J., Lugtenburg J., Belenky M. & Herzfeld J. (2001), Tight Asp-85-Thr-89 Association during the Pump Switch of Bacteriorhodopsin, Proceedings of the National Academy of Sciences 98(4): 1571-1576.artikel in tijdschrift (refereed)
  • Alia A, Matysik J., Soede-Huijbregts C., Baldus M., Raap J., Lugtenburg J., Gast P., Gorkom H.J. van, Hoff A.J. & Groot H.J.M. de (2001), Ultrahigh Field MAS NMR Dipolar Correlation Spectroscopy of the Histidine Residues in Light-Harvesting Complex II from Photosynthetic Bacteria Levels Partial Internal Charge Transfer in the B850/His Complex, Journal of the American Chemical Society 123: 4803-4809.artikel in tijdschrift (refereed)
  • Lieshout M., West C.E., Muhilal Muhilal, Permaesih D., Wang Y., Xu X., Breemen R.B., Creemers A.F.L., Verhoeven M.A. & Lugtenburg J. (2001), Bioefficiency of Beta-Carotene Dissolved in Oil Studied in Children in Indonesia, American Journal of Clinical Nutrition 73: 949-958.artikel in tijdschrift (refereed)
  • Matysik J., Alia A, Gast P., Raap J., Lugtenburg J., Hoff A.J. & Groot H.J.M. de (2001), Photo-CIDNP 13C magic angle spinning NMR on bacterial reaction centres: exploring the electronic structure of the special pair and its surroundings, Biological Chemistry 382: 1271-1276.artikel in tijdschrift (refereed)
  • Soede-Huijbregts C., Laren M. van, Hulsbergen F.B., Raap J. & Lugtenburg J. (2001), Improved Specific Synthesis of [1'-15N]- and [3'-15N]L-Histidine, Journal of Labelled Compounds and Radiopharmaceuticals 44: 831-841.artikel in tijdschrift (refereed)
  • Carravetta M., Eden M., Johannessen O.G., Luthman H., Verdegem P.J.E., Lugtenburg J., Sebald A. & Levitt M.H. (2001), Estimation of Carbon-Carbon Bond Lengths and Medium-Range Internuclear Distances by Solid State Nuclear Magnetic Resonance, Journal of the American Chemical Society 43: 10628-10638.artikel in tijdschrift (refereed)
  • Lansing J.C., Hohwy M., Creemers A.F.L., Lugtenburg J., Herzfeld J. & Griffin R.G. (2001), Determination of Torsion Angles in Membrane Proteins. In: Kiihne S.R., Groot H.J.M. de (Red.) Perspectives on Solid State NMR in Biology: Kluwer Academic Publishers. 185-190.boekdeel
  • Matysik J., Gast P., Lugtenburg J., Hoff A.J. & Groot H.J.M. de (2001), Photochemically induced dynamic nuclear polarization in bacterial photosynthetic reaction centres observed by 13C solid-state NMR. In: Kiihne S.R., Groot H.J.M. (Red.) Perspective on Solid State NMR in Biology. Dordrecht: Kluwer Academic Publishers.boekdeel
  • Griffiths J.M., Bennett A.E., Engelhard M., Siebert F., Raap J., Lugtenburg J., Herzfeld J. & Griffin R.G. (2000), Structural Investigation of the Active Site in Bacteriorhodopsin: Geometric Constraints in the Roles of Asp-85 and Asp-212 in the Proton-Pumping Mechanism from Solid State NMR, Biochemistry 39(2): 362-371.artikel in tijdschrift (refereed)
  • Feng X., Verdegem P.J.E., Eden M., Sandstrom D., Lee Y.K., Bovee-Geurts P.H.M., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (2000), Determination of a molecular torsional angle in the metarhodopsin-I photointermediate of rhodopsin by double-quantum solid-state NMR, Journal of Biomolecular NMR 16(1): 1-8.artikel in tijdschrift (refereed)
  • Jansen F.J.H.M. & Lugtenburg J. (2000), Synthesis and Characterization of all-E-(4,4'-13C2)-Astaxanthin Strategies for Labelling the C15-End Groups of Carotenoids, European Journal of Organic Chemistry: 829-836.artikel in tijdschrift (refereed)
  • Ouwerkerk N., Boom J.H. van, Lugtenburg J. & Raap J. (2000), Chemo-Enzymatic Synthesis of Thymidine 13C-Labelled in the 2'-Deoxyribose Moiety, European Journal of Organic Chemistry: 861-866.artikel in tijdschrift (refereed)
  • Loo M.E. van, Lugtenburg J. & Cornelisse J. (2000), Reactivity of the 5-Hydroacenaphthylene Anion Towards Electrophiles, 2[ ] Single Electron Transfer vs. SN2 Reaction, European Journal of Organic Chemistry: 713-721.artikel in tijdschrift (refereed)
  • Andel III F., Murphy J.T., Haas J.A., McDowell M.T., Hoef K. van der, Lugtenburg J., Lagarias J.C. & Mathies R.A. (2000), Probing the Photoreaction Mechanism of Phytochrome through Analysis of Resonance Raman Vibrational Spectra of Recombinant Analogues, Biochemistry 39(10): 2667-2676.artikel in tijdschrift (refereed)
  • Kandori H., Kinoshita N., Yamazaki Y., Maeda A., Shichida Y, Needleman R., Lanyi J.K., Bizounok M., Herzfeld J., Raap J. & Lugtenburg J. (2000), Local and Distant Protein Structural Changes on Photoisomerization of the Retinal in Bacteriorhodopsin, Proceedings of the National Academy of Science of the United States of America 97(9): 4643-4648.artikel in tijdschrift (refereed)
  • Werkhoven T.M., Siebum A.H.G. & Lugtenburg J. (2000), Specific 13C Isotope Enrichment of Isoprene, European Journal of Organic Chemistry: 2113-2117.artikel in tijdschrift (refereed)
  • Mulder F.M., Heinen W., Duin M. van, Lugtenburg J. & Groot H.J.M. de (2000), Cross-Linking Induced Phase Separation in SAN/SMA Semi-Interpenetrating Polymer Networks Observed by Solid State NMR and Site-Specific Isotope Enrichment, Macromolecules 33: 5544-5548.artikel in tijdschrift (refereed)
  • Wang Yan, Xu X., Lieshout M., West C.E., Lugtenburg J., Verhoeven M.A., Creemers A.F.L., Muhilal Muhilal & Breemen R.B. (2000), A Liquid Chromatography-Mass Spectrometry Method for the Quantification of Bioavailability and Bioconverison of beta-carotene to Retinol in Humans, Analytical Chemistry 72(20): 4999-5003.artikel in tijdschrift (refereed)
  • Alia A, Matysik J., Erkelens C., Hulsbergen F.B., Gast P., Lugtenburg J. & Groot H.J.M. de (2000), Bacteriochlorophyll/imidazole and Chlorophyll/imidazole Complexes Are Negatively Charged in an Apolar Environment, Chemical Physics Letters(330): 325-330.artikel in tijdschrift (refereed)
  • Mathies R.A. & Lugtenburg J. (2000), The Primary Photoreaction of Rhodopsin. In: Stavenga D.G., Grip W.J. de, Pugh E.N. Jr (Red.) Handbook of Biological Physics. Amsterdam: Elsevier Science. 55-90.boekdeel
  • Weesie R.J., Merlin J.C., De Groot H.J.M., Britton G., Lugtenburg J., Jansen F.J.H.M. & Cornard J..P (1999), Resonance Raman spectroscopy and quantum chemical modeling studies of protein-astaxanthin interactions in alpha-crustacyanin (major blue carotenoprotein complex in carapace of lobster, Homarus gammarus), BIOSPECTROSCOPY 5(6): 358-370.artikel in tijdschrift (refereed)
  • Weesie R.J., Merlin J.C., de Groot H.J.M., Britton G., Lugtenburg J., Jansen F.J.H.M. & Cornard J.P. (1999), Quantum chemical modelling and spectroscopic studies of the protein-astaxanthin interactions in alpha-crustacyanin, SPECTROSCOPY OF BIOLOGICAL MOLECULES: NEW DIRECTIONS: 141-142.artikel in tijdschrift (refereed)
  • Alia Alia, Erkelens C., Soede-Huijbregts C., Lugtenburg J., Gast P., Hoff A.J., Gorkom H.J. van & Groot H.J.M. de (1999), 15N-Mas NMR spectroscopy on plant light-harvesting complex enriched with selectively 15N-labelled histidines. Chamonix-Mont Blanc, France. [overig]overig
  • Alia Alia, Matysik J., Soede-Huijbregts C., Erkelens C., Lugtenburg J., Gast P., Hoff A.J., Gorkom H.J. van & Groot H.J.M. de (1999), 15N-Mas NMR spectroscopy on plant light-harvesting complex enriched with selectively 15N-labelled histidines. Chamonix-Mont Blanc, France. [overig]overig
  • Verdegem P.J..E, Bovee-Geurts P.H.M., de Grip W.J., Lugtenburg J. & de Groot H.J.M. (1999), Retinylidene ligand structure in bovine rhodopsin, metarhodopsin-I, and 10-methylrhodopsin from internuclear distance measurements using C-13-labeling and 1-D rotational resonance MAS NMR, BIOCHEMISTRY 38(35): 11316-11324.artikel in tijdschrift (refereed)
  • Feng X., Verdegem P.J.E., Lee Y..K, Helmle M., Shekar S.C., de Groot H.J.M., Lugtenburg J. & Levitt M.H. (1999), Rotational resonance NMR of C-13(2)-labelled retinal: quantitative internuclear distance determination, SOLID STATE NUCLEAR MAGNETIC RESONANCE 14(2): 81-90.artikel in tijdschrift (refereed)
  • Creemers A.F.L., Klaassen C.H.W., Bovee-Geurts P.H.M., Kelle R., Kragl U., Raap J., de Grip W.J., Lugtenburg J. & de Groot H.J.M. (1999), Solid state N-15 NMR evidence for a complex Schiff base counterion in the visual G-protein-coupled receptor rhodopsin, BIOCHEMISTRY 38(22): 7195-7199.artikel in tijdschrift (refereed)
  • Alia Alia, Matysik J., Soede-Huijbregts C., Gast P., Raap J., Lugtenburg J., Groot H.J.M. de & Gorkom H.J. van (1999), Selective 15N-Isotope labelling of histidines in PSII reaction centers of Spirodela Oligorrhiza. (Lezing). Lunteren, The Netherlands, February 8-9-99, poster.overig
  • Soede-Huijbregts C., Raap J., Groot H.J.M. de, Lugtenburg J., Gast P. & Hoff A.J. (1999), 15N solid state NMR spectroscopy on bacterial photosynthetic reaction centers. (Lezing). Lunteren, The Netherlands, February 8-9-99, poster.overig
  • Dijk J.T.M. van, Steggerda S.A., Lugtenburg J. & Cornelisse J. (1999), Substituent-Induced Polarization of Charge in Phenalenyl Anions, Journal of Physical Organic Chemistry 12: 86-94.artikel in tijdschrift (refereed)
  • Dijk J.T.M. van, Steggerda S.A., Lugtenburg J. & Cornelisse J. (1999), Substituent-Induced Polarization of Charge in Phenalenyl Anions, Journal of Physical Organic Chemistry 12: 86-94.artikel in tijdschrift (refereed)
  • Christensen R.L., Goyette M., Gallagher L., Duncan J., DeCoster B., Lugtenburg J., Jansen F.J.H.M. & Hoef K. van der (1999), S1 and S2 States of Apo- and Diapocarotenes, Journal of Physical Chemistry A 103(14): 2399-2407.artikel in tijdschrift (refereed)
  • Heinen W., Ballijns L.N., Wittenburg W.J.A., Winters R., Lugtenburg J. & Duin M. van (1999), Synthesis and Characterization of Carbon-13 Labelled 2-Ethylidene-5-Norbornene Containing EPDM Rubber. Observation of Crosslinking and Oxidation., Polymer 40: 4353-4363.artikel in tijdschrift (refereed)
  • Weesie R.J., Merlin J.C., Lugtenburg J., Britton G., Jansen F.J.H.M. & Cornard J.P. (1999), Semiempirical and Raman Spectroscopic Studies of Carotenoids, Biospectroscopy 5: 19-33.artikel in tijdschrift (refereed)
  • Zune C., Dubois P., Jerome R., Werkhoven T.M. & Lugtenburg J. (1999), Anionic Synthesis of [1,4-poly(diene)-b-Syndiotactic Poly (methyl methacrylate)] Diblock Copolymers: 7Li NMR Study of the Intermediate Reaction of Lithium Poly(diene) Anion with 1,1-Diphenylene, Macromolecular Chemical Physics 200: 460-467.artikel in tijdschrift (refereed)
  • Creemers A.F.L., Klaassen C.H.W., Bovee-Geurts P., Kelle R., Kragl U., Raap J., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (1999), Solid State 15N NMR Evidence for a Complex Schiff Base Counterion in the Visual G-Protein-Coupled Receptor Rhodopsin, Biochemistry 38: 7195-7199.artikel in tijdschrift (refereed)
  • Wang Jia-Sheng, He X., Mulder P.P.J., Boere B.B., Cornelisse J., Lugtenburg J. & Busby W.F. (1999), Comparitive Tumorigenicity of the Cyclopenta-Fused Polycyclic Aromatic Hydrocarbons Aceanthrylene, Dihydroaceanthrylene and Acephenylanthrylene in Preweaning CD-1 and BLU: Ha Mouse Bioassays, Carcinogenesis 20(06): 1137-1141.artikel in tijdschrift (refereed)
  • Kandori H., Kinoshita N., Yamazaki Y., Maeda A., Shichida Y, Needleman R., Lanyi J.K., Bizounok M., Herzfeld J., Raap J. & Lugtenburg J. (1999), Structural Change of Threonine 89 upon Photoisomerization in Bacteriorhodopsin as Revealed by Polarized FTIR Spectroscopy, Biochemistry 38: 9676-9683.artikel in tijdschrift (refereed)
  • Alia Alia, Matysik J., Soede-Huijbregts C., Erkelens C., Lugtenburg J., Gast P., Hoff A.J., Gorkom H.J. van & Groot H.J.M. de (1999), 15N-MAS NMR spectroscopy on plant light-harvesting complex enriched with selectively 15N-labelled histidines (Lezing). Ulm, Germany, October 3-6, 1999, poster.overig
  • Makino C.L., Groesbeek M., Lugtenburg J. & Baylor D.A. (1999), Spectral Tuning in Salamander Visual Pigments Studied with Dihydroretinal Chromophores, Biophysical Journal 77: 1024-1035.artikel in tijdschrift (refereed)
  • Verdegem P.J.E., Bovee-Geurts P., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (1999), Retinylidene Ligand Structure in Bovine Rhodopsin, Metarhodopsin-I and 10-Methylrhodopsin from Internuclear Distance Measurements Using 13C-Labeling and 1-D Rotational Resonance MAS NMR, Biochemistry 38: 11316-11324.artikel in tijdschrift (refereed)
  • Imamoto Y., Hirano T., Imai H., Kandori H., Maeda A., Yoshizawa T., Groesbeek M., Lugtenburg J. & Shichida Y (1999), Effect of Anion Binding on Iodopsin Studied by Low-Temperature Fourier Transform Infrared Spectroscopy, Biochemistry 38: 11749-11754.artikel in tijdschrift (refereed)
  • Raap J., Nieuwenhuis S.A.M., Creemers A.F.L., Hexspoor S., Kragl U. & Lugtenburg J. (1999), Synthesis of Isotopically Labeled L-Phenylalanine and L-Tyrosine, European Journal of Organic Chemistry: 2609-2621.artikel in tijdschrift (refereed)
  • Helmle M., Lee Y.K., Verdegem P.J.E., Feng X., Karlsson T., Lugtenburg J., Groot H.J.M. de & Levitt M.H. (1999), Anomalous Rotational Resonance Spectra in Magic-Angle Spinning NMR, Journal of Magnetic Resonance 140: 379-403.artikel in tijdschrift (refereed)
  • Feng X., Verdegem P.J.E., Lee Y.K., Helmle M., Shekar S.C., Groot H.J.M. de, Lugtenburg J. & Levitt M.H. (1999), Rotational Resonance NMR of 13C2-Labelled Retinal: Quantitative Internuclear Distance Determination, Solid State Nuclear Magnetic Resonance 14: 81-90.artikel in tijdschrift (refereed)
  • Feng X., Verdegem P, Lee Y.K., Helmle M, Shekar S.C., Groot H.J.M. de, Lugtenburg J. & Levitt M.H. (1999), Rotational resonance NMR of 13C2-labelled retinal: quantitative internuclear distance determination, Solid State Nuclear Magnetic Resonance 14: 81-90.artikel in tijdschrift (refereed)
  • Pandey S., Acree W.E. Jr., Scott L.T., Necula A., Fetzer J.C., Mulder P.P.J., Lugtenburg J. & Cornelisse J. (1999), Classification of Select Aceanthrylenes, Acephenananthrylenes and Dicyclopentapyrenes as Alternant Versus Nonalternant Polycyclic Aromatic Hydrocarbons on the Basis of Their Fluorescence Quenching Behavior in the Presence of Nitromethane and Cetylpyridium Cation Selective Quenching Agents, Polycyclic Aromatic Compounds 13: 79-92.artikel in tijdschrift (refereed)
  • Werkhoven T.M., Nispen R. van & Lugtenburg J. (1999), Specific Isotope Enrichment of Methyl Methacrylate, European Journal of Organic Chemistry: 2909-2914.artikel in tijdschrift (refereed)
  • Heinen W., Erkens S.W., Duin M. van & Lugtenburg J. (1999), Model Compounds and 13C NMR Increments for the Characterization of Maleic Anhydride-Grafted Polyolefins, Journal of Polymer Science: Part A: Polymer Chemistry 37: 4368-4385.artikel in tijdschrift (refereed)
  • Wang Jia-Sheng, He X., Mulder P.P.J., Boere B.B., Cornelisse J., Lugtenburg J. & Busby W.F. (1999), Comparative tumorigenicity of the cyclopenta-fused polycyclic aromatic hydrocarbons aceanthrylene, dihydroaceanthrylene and acephenanthrylene in preweanling CD-1 and BLU:Ha mouse bioassays, Carcinogenesis 20: 1137-1141.artikel in tijdschrift (refereed)
  • Pandey S., Acree W.E. Jr., Scott L.T., Necula A., Fetzer J.C., Mulder P.P.J., Lugtenburg J. & Cornelisse J. (1999), Classification of select aceanthrylenes, ace-phenanthrylenes and dicyclopentapyrenes as alternant versus nonalternant polycyclic aromatic hydrocarbons on the basis of their fluorescence quenching behaviour in the presence of nitromethane and cetylpyridinium cation selective quenching agents, Polycyclic Aromatic Compounds 13: 79-92.artikel in tijdschrift (refereed)
  • Weesie R.J., Merlin J.C., Lugtenburg J., Britton G., Groot H.J.M. de, Jansen F.J.H.M. & Cornard J.P. (1999), Resonance Raman spectroscopy and quantum chemical modelling studies of the protein chromophore interactions in a-crustacyanin, the major blue carotenoprotein complex in the carapace of the lobster, Homarus gammarus, Biospectroscopy 5(6): 358.artikel in tijdschrift (refereed)
  • Weesie R.J., Merlin J.C., Groot H.J.M. de, Britton G., Lugtenburg J., Jansen F.J.H.M. & Cornard J.P. (1999), Quantum chemical modelling and psectroscopic studies of the protein astaxanthin interactions in a-crustacyanin. In: Greve J., Puppels G.J., Otto C. (Red.) Spectroscopy of Biological Molecules: New Directions Spectroscopy of Biological Molecules: New Directions. Dordrecht: Kluwer Academic Publishers. 141-142.congresbijdrage (refereed)
  • Verdegem P.J.E., Bovee-Geurts P.H.M., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (1999), Retinylidene Ligand Structure in Bovine Rhodopsin, Metarhodopsin-I and 10 Methylrhodopsin from Internuclear Distance Measurements using 13C labelling and 1-D Rotationan Resonance MAS NMR, Biochemistry 38(35): 11316-11324.artikel in tijdschrift (refereed)
  • Grip W.J. de, Lange F. de, Klaassen C.H.W., Verdegem P.J.E., Wallace-Williams S., Creemers A.F.L., Bergo V., Bovee-Geurts P.H.M., Raap J., Rothschild K.J., Groot H.J.M. de & Lugtenburg J. (1999), Photoactivation of rhodopsin: Interplay between protein and chromophore, Rhodopsins and Phototransduction 224: 102-123.artikel in tijdschrift (refereed)
  • Rossum B.J. van, Steensgaard D, Holzwarth A.R., Soede-Huijbregts C., Schaffner K., Raap J., Lugtenburg J., Gast P., Hoff A.J. & Groot H.J.M. de (1999), Magic angle spinning NMR of Photosynthetic components. In: Greve J., Puppels G.J., Otto C. (Red.) Spectroscopy of Biological Molecules: New Directions Spectroscopy of Biological Molecules: New Directions. Dordrecht: Kluwer Academic Publishers. 201-204.congresbijdrage (refereed)
  • Loo M.E. van, Lugtenburg J. & Cornelisse J. (1999), Reactivity of the Acenaphthylene Dianion towards Electrophiles, Polycyclic Aromatic Compounds 14-15: 109-118.artikel in tijdschrift (refereed)
  • Weesie R.J., Merlin J.C., Groot H.J.M. de, Britton G., Lugtenburg J., Jansen F.J.H.M. & Cornard J.P. (1999), Resonance Raman Spectroscopy and Quantum Chemical Modeling Studies of Protein-Astaxanthin Interactions in alpha-Crustacyanin, Biospectroscopy 5: 358-370.artikel in tijdschrift (refereed)
  • Lugtenburg J., Creemers A.F.L., Verhoeven M.A., Wijk A.A.C. van, Verdegem P.J.E., Monnee M.C.F. & Jansen F.J.H.M. (1999), Synthesis of 13C-Labeled carotenoids and retinoids, Pure and Applied Chemistry 71(12): 2245-2251.artikel in tijdschrift (refereed)
  • Grip W.J. de, Lange F. de, Klaassen C.H.W., Verdegem P.J.M., Wallace-Williams S., Creemers A.F.L., Bergo V., Bovee P.H.M., Raap J., Rothschild K.J., de Groot H.J.M. & Lugtenburg J. (1999), Photoactivation of rhodopsin: Interplay between protein and chromophore Rhodopsins and phototransduction. [ontwerp]ontwerp
  • Soede-Huijbregts C., Laren M. van, Boender G.-J, Cappon H., Raap J., Lugtenburg J., Gast P. & Hoff A.J. (1998), ^1^5N MAS NMR spectroscopy on photosynthetic reaction centers (Lezing). Budapest, Hungary, August 17-22 SY4-P100.overig
  • Alia Alia, Matysik J., Gast P., Lugtenburg J., Gorkom H.J. van, Groot H.J.M. de & Soede-Huijbregts C. (1998), Selective 15N-isotope labelling of histidines in PS II reaction centers of {\it Spirodela oligorrhiza} (Lezing). Lunteren, The Netherlands, December 7-8.overig
  • Nieuwenhuis S.A.M., Hulsebosch R.J., Raap J., Gast P., Lugtenburg J. & Hoff A.J. (1998), Structure of the Y_D Tyrosine Radical in photosystem II - Determination of the orientation of the Phenoxyl Ring by Enantioselective deuteration of the Methylene Group, Journal of the American Chemical Society 120: 829-830.artikel in tijdschrift (refereed)
  • Nieuwenhuis S.A.M., Hulsebosch R.J., Raap J., Gast P., Lugtenburg J. & Hoff A.J. (1998), Determination of the orientation of the phenoxyl ring of Y_D in photosystem II by enantioselective duteration of the methylene group (Lezing). Kansas City, USA, February 22-26.overig
  • Lange F. de, Bovee-Geurts P., Oostrum J. van, Daniel Portier M., Verdegem P.J.E., Lugtenburg J. & Grip W.J. de (1998), An Additional Methyl Group at the 10-Position of Retinal Dramatically Slows Down the Kinetics of the Rhodopsin Photocascade, Biochemistry 37: 1411-1420.artikel in tijdschrift (refereed)
  • Nieuwenhuis S.A.M., Hulsebosch R.J., Raap J., Gast P., Lugtenburg J. & Hoff A.J. (1998), Structure of the YD Tyrosine Radical in Photosystem II. Determination of the Orientation of the Phenoxyl Ring by Enantioselective Deuteration of the Methylene Group, Journal of the American Chemical Society 120: 829-830.artikel in tijdschrift (refereed)
  • Grobner G., Choi G., Burnett I.J., Glaubitz C., Verdegem P.J.E., Lugtenburg J. & Watts A. (1998), Photoreceptor Rhodopsin: Structural and Conformational Study of Its Chromophore 11 cis Retinal in Oriented Membranes by Deuterium Solid State NMR, FEBS Letters 422: 201-204.artikel in tijdschrift (refereed)
  • Kakitani T., Akiyama R., Hatano Y., Imamoto Y., Shichida Y, Verdegem P.J.E. & Lugtenburg J. (1998), Deuterium Substitution Effect on the Excited State Dynamics of Rhodopsin, Journal of Physical Chemistry B 102: 1334-1339.artikel in tijdschrift (refereed)
  • Hu J.G., Sun B.Q., Bizounok M., Hatcher M.E., Lansing J.C., Raap J., Verdegem P.J.E., Lugtenburg J., Griffin R.G. & Herzfeld J. (1998), Early and Late M Intermediates in the Bacteriorhodopsin Photocycle: A Solid State NMR Study, Biochemistry 37: 8088-8096.artikel in tijdschrift (refereed)
  • Zune C., Dubois P., Jerome R., Kriz J., Dybal J., Lochmann L., Janata M., Vlcek P., Werkhoven T.M. & Lugtenburg J. (1998), Study of the Propogation Center in the Anionic Polymerization of (meth)Acrylic Monomers: NMR and MO LCAO Study of the Interaction of di-tert-Butyl 2-Lithio-2,4,4-trimethylglutarate and the Living Poly(tert-butyl methacrylate) Oligomers with Lithium 2-(2-Methoxyethoxy)ethoxide in Tetrahydrofuran, Macromolecules 31: 2731-2743.artikel in tijdschrift (refereed)
  • Zune C., Dubois P., Jerome R., Kriz J., Dybal J., Lochmann L., Janata M., Vlcek P., Werkhoven T.M. & Lugtenburg J. (1998), Study of the Propogation Center in the Anionic Polymerization of (meth)Acrylic Monomers: NMR and MNDO Study of the Complexes of di-tert-Butyl 2-Lithio-2,4,4-trimethylglutarate and of the Living Poly(tert-Butyl Methacrylate) Oligomers with Lithium, Macromolecules 31: 2744-2755.artikel in tijdschrift (refereed)
  • Lugtenburg J. & Groot H.J.M. de (1998), Characterization of Photosynthetic Reaction Centers with Specific Isotope Labels, Photosynthesis Research 55: 241-245.artikel in tijdschrift (refereed)
  • Heinen W., Wenzel C., Rosenmoller C.H., Mulder F.M., Boender G.-J, Lugtenburg J., Groot H.J.M. de, Duin M. van & Klumperman B. (1998), Solid State NMR Study of Miscibility and Phase Separation in Blends and Semi-Interpenetrating Networks of 13C Labeled Poly(Styrene-co-Acrylonitrile) and Poly(styrene-co-Maleic Anhydride), Macromolecules 31: 7404-7412.artikel in tijdschrift (refereed)
  • Mulder F.M., Heinen W., Duin M. van, Lugtenburg J. & Groot H.J.M. de (1998), Spin Diffusion with 13C Selection and Detection for the Characterization of Morphology in Labeled Polymer Blends with MAS NMR, Photosynthesis Research 120: 12891-12894.artikel in tijdschrift (refereed)
  • Pijnappel W.W.M., Folkers G.E., Jonge W.J. de, Verdegem P.J.E., Laat S.W. de, Lugtenburg J., Hendriks H.F.J., Saag P.T. van der & Durston A.J. (1998), Metabolism to a Response Pathway Selective Retinoid Ligand during Axial Pattern Formation, Proceedings of the National Academy of Science of the United States of America 95: 15424-15429.artikel in tijdschrift (refereed)
  • Lugtenburg J. & Groot H.J.M. de (1998), Characterization of photosynthetic reaction centers with specific isotope labels, Photosynthesis Research 55: 241-245.artikel in tijdschrift (refereed)
  • Heinen W., Duin M. van, Rosenmoller C.H., Wenzel C., Groot H.J.M. de & Lugtenburg J. (1998), 13C NMR Study of the Grafting of 13C labeled Maleic Anhydride onto PE, PP and EPM, Macromolecules 129: 119-125.artikel in tijdschrift (refereed)
  • Mulder F.M., Heinen W., Duin M. van, Lugtenburg J. & Groot H.J.M. de (1998), Spin Diffusion with 13C Selection and Detection for the characterization of Morphology in labeled Polymer Blends with MAS NMR, Journal of American Chemical Society 120: 12891-12894.artikel in tijdschrift (refereed)
  • Heinen W., Wenzel C., Rosenmoller C.H., Mulder F.M., Boender G.-J, Lugtenburg J., Duin M. van, Klumperman B. & Groot H.J.M. de (1998), Solid State NMR Study of Miscibility and phase separation in Blends and Semi Interpenetrating Networks of 13C labeled Poly(styrene-co-acrylonitrile) and Poly(styrene-co-maleic anhydride), Macromolecules 31(21): 7404-7412.artikel in tijdschrift (refereed)
  • Alia Alia, Matysik J., Soede-Huijbregts C., Gast P., Raap J., Lugtenburg J., Groot H.J.M. de & Gorkom H.J. van (1998), Selective 15N-Isotope Labelling of Histidines in PSII Reaction Centers of Spirodela Oligorrhiza, Proceedings of the XIth International Congress on Photosynthesis.abstract
  • Boers R.B., Gast P., Hoff A.J., Groot H.J.M. de & Lugtenburg J. (1998), Synthesis and NMR spectroscopy of labeled ubiquinones in Photosynthesis studies, Proceedings of the XIth International Congress on Photosynthesis.abstract
  • Heinen W., Duin M. van, Rosenmuller C.H., Wenzel C., Groot H.J.M. de & Lugtenburg J. (1998), 13C NMR Study of the Grafting of 13C Maleic Anhydride onto PE, PP and EPM, Macromolecular Symposium 129: 119-125.artikel in tijdschrift (refereed)
  • Loo M.E. van, Lugtenburg J. & Cornelisse J. (1998), Reactivity of the 5-Hydroacenaphthylene Anion towards Electrophiles, European Journal of Organic Chemistry: 1907-1914.artikel in tijdschrift (refereed)
  • Loo M.E. van, Lugtenburg J. & Cornelisse J. (1998), Reactivity of the 5-Hydroacenaphthylene Anion towards Electrophiles, European Journal of Organic Chemistry: 1907-1914.artikel in tijdschrift (refereed)
  • Bautista J.A., Chynwat V., Cua A., Jansen F.J.H.M., Lugtenburg J., Gosztola D., Wasielewski M.R. & Frank H.A. (1998), The Spectroscopic and Photochemical Properties of Locked-15,15'-cis-Sphaeroidene in Solution and Incorporated into the Reaction Center of Rhodobacter Sphaeroides R-26.1, Photosynthesis Research 55: 49-65.artikel in tijdschrift (refereed)
  • Lin S.W., Groesbeek M., Hoef K. van der, Verdegem P.J.E., Lugtenburg J. & Mathies R.A. (1998), Vibrational Assigment of Torsional Normal Modes of Rhodopsin: Probing Excited-State Isomerization Dynamics along the Reactive C11=C12 Torsion Coordinate, Journal of Physical Chemistry B 102: 2787-2806.artikel in tijdschrift (refereed)
  • Liu X.M., Lee M.J., Coleman M. ', Rath P., Nilsson A., Fischer W.B., Bizounok M., Herzfeld J., Karstens W.F.J., Raap J., Lugtenburg J. & Rothschild K.J. (1998), Detection of Threonine Structural Changes upon Formation of the M-Intermediate of Bacteriorhodopsin: Evidence for Assigment to Thr-89, Biochimica et Biophysica Acta : Bioenergetics 1365(3): 363-372.artikel in tijdschrift (refereed)
  • Soede-Huijbregts C., Cappon J.J., Boender G.-J, Raap J., Gast P., Hoff A.J., Lugtenburg J. & Groot H.J.M. de (1998), 15N MAS NMR spectroscopy of {[n-25N]} and {[t-15N]} histidine labelled bacterial photosynthetic reaction centers. In: Garab G. (Red.) Photosynthesis: Mechanisms and Effects, Vol. II. Dordrecht, The Netherlands: Kluwer Academic Publishers. 754-762.boekdeel
  • Boers R.B., Gast P., Hoff A.J., Groot H.J.M. de & Lugtenburg J. (1998), Synthesis and NMR spectroscopy of labeled ubiquinones in photosynthesis studies. In: Garab G. (Red.) Photosynthesis: Mechanisms and Effects, Vol. II. Dordrecht, The Netherlands: Kluwer Academic Publishers. 881-884.boekdeel
  • Alia A., Matysik J., Soede-Huijbregts C., Gast P., Raap J., Lugtenburg J., Groot H.J.M. de & Gorkom H.J. van (1998), Selective 15N-isotope labelling of histidines in PSII reaction centers of {it\ Spirodela oligorrhiza}. In: Garab G. (Red.) Photosynthesis: Mechanisms and Effects, Vol. II. Dordrecht, The Netherlands: Kluwer Academic Publishers. 1009-1012.boekdeel
  • Feng X., Verdegem P.J.E., Lee Y.K., Sandstrom D., Eden M., Bovee-Geurts P., Grip W.J. de, Lugtenburg J., Groot H.J.M. de & Levitt M.H. (1997), Direct Determination of a Molecular Torsional Angle in the Membrane Protein Rhodopsin by Solid-State NMR, Journal of the American Chemical Society 119: 6853-6857.artikel in tijdschrift (refereed)
  • Verdegem P.J.E., Lugtenburg J. & Groot H.J.M. de (1997), The use of Isotopes for probing Ligand-protein interactions and Ligand structure: The rhodopsin G-protein coupled Membrane receptor paradigm, Pharmaceutical Research 26.artikel in tijdschrift
  • Weesie R.J., Jansen F.J.H.M., Merlin J.C., Lugtenburg J., Britton G. & Groot H.J.M. de (1997), 13C Magic Angle Spinning NMR Analysis and Quantum Chemical Modeling of the Bathochromic Shift of Astaxathin in a-Crustacyanin, the Blue Carotenoprotein Complex in the Carapace of the Lobster Homarus gammarus, Biochemistry 36: 7288-7296.artikel in tijdschrift (refereed)
  • Britton G., Weesie R.J., Askin D., Warburton J.D., Gallardo-Guerrero L., Jansen F.J.H.M., Groot H.J.M. de, Lugtenburg J., Cornard J.P. & Merlin J.C. (1997), Carotenoid blues: Structural studies on carotenoproteins, Pure and Applied Chemistry 69: 2075-2084.artikel in tijdschrift (refereed)
  • vanRossum B.J., vanLiemt W.B.S., Boender G.J., Gast P., Hoff A.J., Lugtenburg J. & deGroot H.J.M. (1995), C-13 MAS NMR relaxation study of the Q(A) binding in Rhodobacter sphaeroides R26 reaction centers, PHOTOSYNTHESIS: FROM LIGHT TO BIOSPHERE, VOL I: 899-902.artikel in tijdschrift (refereed)
  • VANLIEMT W.B.S., BOENDER G.J., GAST P., HOFF A.J., LUGTENBURG J. & DEGROOT H.J.M. (1995), C-13 MAGIC-ANGLE-SPINNING NMR CHARACTERIZATION OF THE FUNCTIONALLY ASYMMETRIC Q(A) BINDING IN RHODOBACTER-SPHAEROIDES R26 PHOTOSYNTHETIC REACTION CENTERS USING SITE-SPECIFIC C-13-LABELED UBIQUINONE-L0, BIOCHEMISTRY 34(32): 10229-10236.artikel in tijdschrift (refereed)
  • BRUDLER R., DEGROOT H.J.M., VANLIEMT W.B.S., GAST P., HOFF A.J., LUGTENBURG J. & GERWERT K. (1995), FTIR SPECTROSCOPY SHOWS WEAK SYMMETRICAL HYDROGEN-BONDING OF THE Q(B) CARBONYL GROUPS IN RHODOBACTER-SPHAEROIDES R26 REACTION CENTERS, FEBS LETTERS 370(1-2): 88-92.artikel in tijdschrift (refereed)
  • WEESIE R.J., ASKIN D., JANSEN F.J.H.M., DEGROOT H.J.M., LUGTENBURG J. & BRITTON G. (1995), PROTEIN-CHROMOPHORE INTERACTIONS IN ALPHA-CRUSTACYANIN, THE MAJOR BLUE CAROTENOPROTEIN FROM THE CARAPACE OF THE LOBSTER, HOMARUS-GAMMARUS - A STUDY BY C-13 MAGIC-ANGLE-SPINNING NMR, FEBS LETTERS 362(1): 34-38.artikel in tijdschrift (refereed)
  • SHOCHAT S., GAST P., HOFF A.J., BOENDER G.J., VANLEEUWEN S., VANLIEMT W.B.S., VIJGENBOOM E., RAAP J., LUGTENBURG J. & DEGROOT H.J.M. (1995), C-13 MAS NMR EVIDENCE FOR A HOMOGENEOUSLY ORDERED ENVIRONMENT OF TYROSINE-M210 IN REACTION CENTERS OF RHODOBACTER-SPHAEROIDES, SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 51(1): 135-144.artikel in tijdschrift (refereed)
  • BRUDLER R., DEGROOT H.J.M., VANLIEMT W.B.S., STEGGERDA W.F., ESMEIJER R., GAST P., HOFF A.J., LUGTENBURG J. & GERWERT K. (1994), ASYMMETRIC BINDING OF THE 1-C=0 AND 4-C=0 GROUPS OF Q(A) IN RHODOBACTER-SPHAEROIDES-R26 REACTION CENTERS MONITORED BY FOURIER-TRANSFORM INFRARED-SPECTROSCOPY USING SITE-SPECIFIC ISOTOPICALLY LABELED UBIQUINONE-10, EMBO JOURNAL 13(23): 5523-5530.artikel in tijdschrift (refereed)
  • SMITH S.O., DEGROOT H., GEBHARD R. & LUGTENBURG J. (1992), MAGIC ANGLE SPINNING NMR-STUDIES ON THE METARHODOPSIN-II INTERMEDIATE OF BOVINE RHODOPSIN - EVIDENCE FOR AN UNPROTONATED SCHIFF-BASE, PHOTOCHEMISTRY AND PHOTOBIOLOGY 56(6): 1035-1039.artikel in tijdschrift (refereed)
  • DEGROOT H.J.M., GEBHARD R., VANDERHOEF I., HOFF A.J., LUGTENBURG J., VIOLETTE C.A. & FRANK H.A. (1992), C-13 MAGIC ANGLE SPINNING NMR EVIDENCE FOR A 15,15'-CIS CONFIGURATION OF THE SPHEROIDENE IN THE RHODOBACTER-SPHAEROIDES PHOTOSYNTHETIC REACTION CENTER, BIOCHEMISTRY 31(49): 12446-12450.artikel in tijdschrift (refereed)
  • FISCHER M.R., DEGROOT H.J.M., RAAP J., WINKEL C., HOFF A.J. & LUGTENBURG J. (1992), C-13 MAGIC ANGLE SPINNING NMR-STUDY OF THE LIGHT-INDUCED AND TEMPERATURE-DEPENDENT CHANGES IN RHODOBACTER-SPHAEROIDES R26 REACTION CENTERS ENRICHED IN [4'-C-13]TYROSINE, BIOCHEMISTRY 31(45): 11038-11049.artikel in tijdschrift (refereed)
  • SMITH S.O., COURTIN J., DEGROOT H., GEBHARD R. & LUGTENBURG J. (1991), C-13 MAGIC-ANGLE SPINNING NMR-STUDIES OF BATHORHODOPSIN, THE PRIMARY PHOTOPRODUCT OF RHODOPSIN, BIOCHEMISTRY 30(30): 7409-7415.artikel in tijdschrift (refereed)
  • DEGROOT H.J.M., SMITH S.O., KOLBERT A.C., COURTIN J.M.L., WINKEL C., LUGTENBURG J., HERZFELD J. & GRIFFIN R.G. (1991), ITERATIVE FITTING OF MAGIC-ANGLE-SPINNING NMR-SPECTRA, JOURNAL OF MAGNETIC RESONANCE 91(1): 30-38.artikel in tijdschrift (refereed)
  • GEBHARD R., VANDERHOEF K., VIOLETTE C.A., DEGROOT H.J.M., FRANK H.A. & LUGTENBURG J. (1991), C-13 MAGIC ANGLE SPINNING NMR EVIDENCE FOR A 15,15'-Z CONFIGURATION OF THE SPHEROIDENE CHROMOPHORE IN THE RHODOBACTER-SPHAEROIDES REACTION CENTER - SYNTHESIS OF C-13-LABELED AND H-2-LABELED SPHEROIDENES, PURE AND APPLIED CHEMISTRY 63(1): 115-122.artikel in tijdschrift (refereed)
  • DEGROOT H.J.M., SMITH S.O., COURTIN J., VANDENBERG E., WINKEL C., LUGTENBURG J., GRIFFIN R.G. & HERZFELD J. (1990), SOLID-STATE C-13 AND N-15 NMR-STUDY OF THE LOW PH FORMS OF BACTERIORHODOPSIN, BIOCHEMISTRY 29(29): 6873-6883.artikel in tijdschrift (refereed)
  • DEGROOT H.J.M., RAAP J., WINKEL C., HOFF A.J. & LUGTENBURG J. (1990), MAGIC-ANGLE-SPINNING C-13 NMR WITH ATOMIC RESOLUTION OF A PHOTOSYNTHETIC REACTION CENTER ENRICHED IN [4'-C-13]TYROSINE, CHEMICAL PHYSICS LETTERS 169(4): 307-310.artikel in tijdschrift (refereed)
  • SMITH S.O., DEGROOT H.J.M., GEBHARD R., COURTIN J.M.L., LUGTENBURG J., HERZFELD J. & GRIFFIN R.G. (1989), STRUCTURE AND PROTEIN ENVIRONMENT OF THE RETINAL CHROMOPHORE IN LIGHT-ADAPTED AND DARK-ADAPTED BACTERIORHODOPSIN STUDIED BY SOLID-STATE NMR, BIOCHEMISTRY 28(22): 8897-8904.artikel in tijdschrift (refereed)
  • DEGRIP W.J., GRAY D., GILLESPIE J., BOVEE P.H.M., VANDENBERG E.M.M., LUGTENBURG J. & ROTHSCHILD K.J. (1988), PHOTOEXCITATION OF RHODOPSIN - CONFORMATION CHANGES IN THE CHROMOPHORE, PROTEIN AND ASSOCIATED LIPIDS AS DETERMINED BY FTIR DIFFERENCE SPECTROSCOPY, PHOTOCHEMISTRY AND PHOTOBIOLOGY 48(4): 497-504.artikel in tijdschrift (refereed)

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