Fredj Ben Bdira
Gastonderzoeker
- Naam
- Dr. F. Ben Bdira
- Telefoon
- +31 71 527 2727
- f.ben.bdira@lic.leidenuniv.nl
- ORCID iD
- 0000-0003-0205-4144
Gastonderzoeker
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Macromolecular Biochemistry
- Ben Bdira F., Erkelens A.M., Qin L., Volkov A.N., Lippa A.M., Bowring N., Boyle A.L., Ubbink M., Dove S.L. & Dame R.T. (2021), Novel anti-repression mechanism of H-NS proteins by a phage protein, Nucleic Acids Research 49(18): 10770-10784.
- Marneth K., Elst H. van den, Cramer-Blok A.J., Codee J.D.C., Overkleeft H.S., Aerts J.M.F.G., Ubbink M. & Ben Bdira F. (2021), Tuning the transglycosylation reaction of a GH11 xylanase by a delicate enhancement of its thumb flexibility, ChemBioChem 22(10): 1743-1749.
- Ubbink M., Ben Bdira F, Waudby C.A., Volkov A.N., Schröder S.P., Ab E., Codée J.D.C., Overkleeft H.S., Aerts J.M.F.G. & Ingen H. van (2020), Dynamics of ligand binding to a rigid glycosidase, Angewandte Chemie (International Edition) 59(46): 20508-20514.
- Qin L., Ben Bdira F., Sterckx Y.G.J., Volkov A.N., Vreede J., Giachin G., Schaik P., Ubbink M. & Dame R.T. (2020), Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins, Nucleic Acids Research 48(4): 2156-2172.
- Qin L., Erkelens A.M., Ben Bdira F. & Dame R.T. (2019), The architects of bacterial DNA bridges: a structurally and functionally conserved family of proteins, Open Biology 9(12): 190223.
- Ben Bdira F., Artola Perez de Azana M.E., Overkleeft H.S., Ubbink M. & Aerts J.M.F.G. (2018), Distinguishing the differences in beta-glycosylceramidase folds, dynamics, and actions informs therapeutic uses, Journal of Lipids 59(12): 2262-2276.
- Ben Bdira F. (20 februari 2018), Understanding functional dynamics and conformational stability of beta-glycosidases (Dissertatie. Macromolecular Biochemistry, Science, Leiden University). Promotor(en) en copromotor(en): Ubbink M., Aerts J.M.F.G.
- Ben Bdira F., Kallemeijn W.W., Oussoren S.V., Scheij S., Bleijlevens B., Florea B.I., Roomen C.P.A.A. van, Ottenhoff R., Kooten M.J.F.M. van, Walvoort M.T.C., Witte M.D., Boot R.G., Ubbink M., Overkleeft H.S. & Aerts J.M.F.G. (2017), Stabilization of Glucocerebrosidase by Active Site Occupancy, ACS Chemical Biology 12(7): 1830-1841.
- Ben Bdira F., Jiang J., Kallemeijn W.W., Haan A. de, Florea B.I., Bleijlevens B., Boot R.G., Overkleeft H.S., Aerts J.M.F.G. & Ubbink M. (2016), Hydrophobic interactions contribute to conformational stabilization of endoglycoceramidase II by mechanism-based probes, Biochemistry 55(34): 4823-4835.
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