Dennis Wander
Onderzoeker/ gast
- Naam
- Dr. D.P.A. Wander
- Telefoon
- +31 71 527 2727
- d.p.a.wander@lic.leidenuniv.nl
- ORCID iD
- 0000-0003-3881-5240
Onderzoeker/ gast
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Bio-organic Synthesis
- Gelder M.A., Zanden S.Y. van der, Vriends M.B.L., Wagensveld R.A., Marel G.A. van der, Codee J.D.C., Overkleeft H.S., Wander D.P.A. & Neefjes J.J.C. (2023), Re-exploring the anthracycline chemical space for better anti-cancer compounds, Journal of Medicinal Chemistry 66(16): 11390–11398.
- Wander D.P.A., Zanden S.Y. van der, Vriends M.B.L. Veen B.C. van, Vlaming J.G.C., Bruyning T., Hansen T., Marel G.A. van der, Overkleeft H.S., Neefjes J.J.C. & Codée J.D.C. (2021), Synthetic (N,N-dimethyl)doxorubicin glycosyl diastereomers to dissect modes of action of anthracycline anticancer drugs, Journal of Organic Chemistry (JOC) 86(8): 5757-5770.
- Qiao X., Zanden S.Y. van der, Wander D.P.A., Borràs D.M., Song J.Y., Li X., Duikeren S. van, Gils N. van, Rutten A., Herwaarden T. van, Tellingen O. van, Giacomelli E., Bellin M., Orlova V., Tertoolen L.G.J., Gerhardt S., Akkermans J.J., Bakker J.M., Zuur C.L., Pang B., Smits A.M., Mummery C.L., Smit L., Arens R., Li J., Overkleeft H.S. & Neefjes J.J.C. (2020), Uncoupling DNA damage from chromatin damage to detoxify doxorubicin, Proceedings of the National Academy of Sciences 117(26): 15182-15192.
- Wander D.P.A., Zanden S.Y. van der, Marel G.A. van der, Overkleeft H.S., Neefjes J.J.C. & Codee J.D.C. (2020), Doxorubicin and aclarubicin: shuffling anthracycline glycans for improved anticancer agents, Journal of Medicinal Chemistry 63(21): 12814-12829.
- Maurits E., Graaff M.J. van de, Maiorana S., Wander D.P.A., Dekker P.M., Zanden S.Y. van der, Florea B.I., Neefjes J.J.C., Overkleeft H.S. & Kasteren S.I. van (2020), Immunoproteasome inhibitor-doxorubicin conjugates target multiple myeloma cells and release doxorubicin upon low-dose photon irradiation, Journal of the American Chemical Society 142(16): 7250-7253.
- Wander D.P.A. (19 november 2019), Understanding Anthracyclines: Synthesis of a Focused Library of Doxorubicin/Aclarubicin - Inspired Structures (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Overkleeft H.S. & Neefjes J.J.C., Codée J.D.C.
- Hansen T., Lebedel L., Remmerswaal W.A., Vorm S. van der, Wander D.P.A., Somers M., Overkleeft H.S., Filippov D.V., Désiré J., Mingot A., Bleriot Y., Marel G.A. van der, Thibaudeau S. & Codée J.D.C. (2019), Defining the SN1 Side of Glycosylation Reactions: Stereoselectivity of Glycopyranosyl Cations, ACS Central Science 5(5): 781-788.
- Beenakker T.J.M., Wander D.P.A., Codée J.D.C., Aerts J.M.F.G., Marel G.A. van der & Overkleeft H.S. (2018), Synthesis of Carba-Cyclophellitols: a New Class of Carbohydrate Mimetics, European Journal of Organic Chemistry 2018(20-21): 2504-2517.
- Beenakker T.J.M., Wander D.P.A., Offen W.A., Artola Perez de Azanza M.E., Raich L., Guimaraes da Lomba Ferraz M.J., Li K.Y., Houben J.H.P.M., Rijssel E.R. van, Hansen T., Marel G.A. van der, Codee J.D.C., Aerts J.M.F.G., Rovira C., Davies G.J. & Overkleeft H.S. (2017), Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors, Journal of the American Chemical Society 139(19): 6534-6537.