Thomas Hansen
Promovendus
- Naam
- Dr. T. Hansen
- Telefoon
- +31 71 527 4481
- t.hansen@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-6291-1569
Promovendus
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- Hansen T. (25 november 2020), Glycosyl cations in glycosylation reactions (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Promotor(en) en Copromotor(en): Codée, J.D.C., Marel, G.A. van der.
- Hansen T., Ofman T.P., Vlaming J.G.C., Gagarinov I.A., Beek J. van, Goté T.A., Tichem J.M., Ruijgrok G., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2020), Reactivity-Stereoselectivity Mapping for the Assembly of Mycobacterium Marinum Lipooligosaccharides, Angewandte Chemie International Edition 60(2): 937-945.
- Hansen T., Vermeeren P., Haim A., Dorp M.J.H. van, Codee J.D.C., Bickelhaupt F.M. & Hamlin T.A. (2020), Regioselectivity of Epoxide Ring-Openings via S(N)2 Reactions Under Basic and Acidic Conditions, European Journal of Organic Chemistry 2020(25): 3822-3828.
- Hansen T., Elferink H., Hengst J.M.A. van, Houthuijs K.J., Remmerswaal W.A., Kromm A., Berden G., Vorm S. van der, Rijs A.M., Overkleeft H.S., Filippov D.V., Rutjes F.P.J.T., Marel G.A. van der, Martens J., Oomens J., Codée J.D.C. & Boltje T.J. (2020), Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions, Nature Communications 11(1): 2664.
- Geus M.A.R. de, Maurits E., Sarris A.J.C., Hansen T., Kloet M.S., Kamphorst K., Hoeve W. ten, Robillard M.S., Pannwitz A., Bonnet S.A., Codée J.D.C., Filippov D.V., Overkleeft H.S. & Kasteren S.I. van (2020), Fluorogenic Bifunctional Trans-cyclooctenes as Efficient Tools for Investigating Click-to-Release Kinetics, Chemistry-a European Journal 26(44): 9900-9904.
- Liu H., Hansen T., Zhou S.Y., Wen G.E., Liu X.X., Zhang Q.J., Codée J.D.C., Schmidt R.R. & Sun J.S. (2019), Dual-Participation Protecting Group Solves the Anomeric Stereocontrol Problems in Glycosylation Reactions, Organic Letters 21(21): 8713-8717.
- Sun J.S., Chen J., Hansen T., Zhang Q.J., Liu D.Y., Sun Y., Yan H., Codee J.D.C. & Schmidt R.R. (2019), 1‐Picolinyl‐5‐azido Thiosialosides: Versatile Donors for the Stereoselective Construction of Sialyl Linkages, Angewandte Chemie 58(47): 17000-17008.
- Zhang Q., Gimeno A., Santana D., Wang Z., Valdés-Balbin Y., Rodríguez-Noda L.M., Hansen T., Kong L., Shen M., Overkleeft H.S., Vérez-Bencomo V., Marel G.A. van der, Jiménez-Barbero J., Chiodo F. & Codée J.D.C. (2019), Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction, ACS Central Science 5(8): 1407-1416.
- Vorm S. van der, Hansen T., Hengst J.M.A. van, Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2019), Acceptor reactivity in glycosylation reactions, Chemical Society Reviews 48(17): 4688-4706.
- Ham A. van der, Hansen T., Lodder G., Codée J.D.C., Hamlin T.A. & Filippov D.V. (2019), Computational and NMR Studies on the Complexation of Lithium Ion to 8‐Crown‐4, CHEMPHYSCHEM 20(16): 2103-2109.
- Hansen T., Lebedel L., Remmerswaal W.A., Vorm S. van der, Wander D.P.A., Somers M., Overkleeft H.S., Filippov D.V., Désiré J., Mingot A., Bleriot Y., Marel G.A. van der, Thibaudeau S. & Codée J.D.C. (2019), Defining the SN1 Side of Glycosylation Reactions: Stereoselectivity of Glycopyranosyl Cations, ACS Central Science 5(5): 781-788.
- Vorm S. van der, Hansen T., Rijssel E.R. van, Dekkers R., Madern J.M., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2019), Furanosyl oxocarbenium ion Conformational Energy Landscape maps as a tool to study the glycosylation stereoselectivity of 2-azidofuranoses, 2-fluorofuranoses and methyl furanosyl uronates, Chemistry-a European Journal 25(29): 7149-7157.
- Madern J.M., Hansen T., Rijssel E.R. van, Kistemaker H.A.V., Vorm S. van der, Overkleeft H.S., Marel G.A. van der, Filippov D.V. & Codee J.D.C. (2019), Synthesis, Reactivity, and Stereoselectivity of 4-Thiofuranosides, Journal of Organic Chemistry 84(3): 1218-1227.
- Artola M., Kuo C.L., McMahon S.A., Oehler V., Hansen T., Lienden M.J.C. van der, He X., Elst H. van den, Florea B.I., Kermode A.R., Marel G.A. van der, Gloster T.M., Codée J.D.C., Overkleeft H.S. & Aerts J.M.F.G. (2018), New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes, Chemistry-a European Journal 24(71): 19081-19088.
- Sarris A.J.C., Hansen T., Geus M.A.R. de, Maurits E., Doelman W., Overkleeft H.S., Codée J.D.C., Filippov D.V. & Kasteren S.I. van (2018), Fast and pH-Independent Elimination of trans-Cyclooctene by Using Aminoethyl-Functionalized Tetrazines, Chemistry-a European Journal 24(68): 18075-18081.
- Rooden E.J. van, Kreekel R., Hansen T., Janssen A.P.A., Esbroeck A.C.M. van, Dulk H. den, Berg R.J.B.H.N. van den, Codee J.D.C. & Stelt M. van der (2018), Two-step activity-based protein profiling of diacylglycerol lipase, Organic and Biomolecular Chemistry 16: 5250-5253.
- Schröder S.P., Wu L., Artola Perez de Azanza M.E., Hansen T., Offen W.A., Guimaraes Da Lomba Ferraz M.J., Li K.-Y., Aerts J.M.F.G., Marel G.A. van der, Codee J.D.C., Davies G.J. & Overkleeft H.S. (2018), Gluco-1H-imidazole: A New Class of Azole-Type beta-Glucosidase Inhibitor, Journal of the American Chemical Society 140(15): 5045-5048.
- Schröder S.P., Kallemeijn W.W., Debets M.F., Hansen T., Sobala L.F., Hakki Z., Williams S.J., Beenakker T.J.M., Aerts J.M.F.G., Marel G.A. van der, Codée J.D.C., Davies G.J. & Overkleeft H.S. (2018), Spiro-epoxyglycosides as activity-based probes for glycoside hydrolase family 99 endomannosidase/endomannanase, Chemistry 24(39): 9983-9992.
- Beenakker T.J.M., Wander D.P.A., Offen W.A., Artola Perez de Azanza M.E., Raich L., Guimaraes Da Lomba Ferraz M.J., Li K.Y., Houben J.H.P.M., Rijssel E.R. van, Hansen T., Marel G.A. van der, Codee J.D.C., Aerts J.M.F.G., Rovira C., Davies G.J. & Overkleeft H.S. (2017), Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors, Journal of the American Chemical Society 139(19): 6534-6537.
- Hagen B., Vorm S. van der, Hansen T., Marel G.A. van der & Codée J.D.C. (2017), Stereoselective glycosylations - Additions to oxocarbenium ions. In: Bennett C. (red.) Selective Glycosylations – Synthetic Methods and Catalysts.: Wiley.
- Vorm S. van der, Hansen T., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), The Influence of Acceptor Nucleophilicity on the Glycosylation Reaction Mechanism, Chemical Science 2017(8): 1867-1875.
- Mukhopadhyay P., Baggelaar M., Erdelyi K., Cao Z., Cinar R., Fezza F., Ignatowska-Jankowska B., Wilkerson J., Gils N. van, Hansen T., Ruben M., Soethoudt M., Heitman L., Kunos G., Maccarrone M., Lichtman A., Pacher P. & Stelt M. van der (2016), The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity, British Journal of Pharmacology 173(3): 446–458.
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