Universiteit Leiden

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Tasia Amelia

PhD candidate / guest

Name
T. Amelia MSc
Telephone
+31 71 527 4324
E-mail
t.amelia@lacdr.leidenuniv.nl

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More information about Tasia Amelia

I studied Pharmacy in Andalas University for Bachelor’s program starting from 2008. During the bachelor study, I did the research in analytical chemistry laboratory, observing the effect of herbs (Cuminum cyminum L., Curcuma zedoaria Rosc., and Curcuma mangga Val.) supplementation in gradient concentration to cow’s feed, which  the effects were shown in cow’s mastitis condition, heavy metals level in milk, and milk production volume.
After my graduation, I continued with the apothecary program and followed by taking master program in Pharmaceutical Chemistry, Bandung Institute of Technology. I did research about in silico study of epitopes from Listeriolysin O as the NSCLC lung cancer vaccine and obtained my master degree in 2015. Later on, I worked as a young lecturer in the institute, focused on Pharmaceutical Chemistry.
I started as a PhD student in 2017 under the supervision of Prof. Ijzerman, Dr. van der Es, and Dr. van Westen in the medicinal chemistry group. I work on organic chemistry and molecular modeling approaches to understand the activation mechanism of G protein-coupled receptor, especially adenosine receptors. Some molecules were synthesized to be later tested for its affinity and efficacy in the receptors, and computation simulations were done to have a better insight into those molecule’s binding in the receptor using crystal structures that has been obtained in-house and from database, and combined approaches may explain the importance of each group and residue in the activity.

PhD candidate / guest

  • Wiskunde en Natuurwetenschappen
  • Leiden Academic Centre for Drug Research
  • LACDR/Medicinal Chemistry

Work address

Gorlaeus Building
Einsteinweg 55
2333 CC Leiden
Room number GE4.11

Contact

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