Universiteit Leiden

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Mónica Varela Álvarez

Postdoc / Marie Curie fellow

Name
Dr. M. Varela Álvarez
Telephone
+31 71 527 4950
E-mail
m.varela.alvarez@biology.leidenuniv.nl

My research focuses on the study of host-pathogen interaction using larval zebrafish as a model of bacterial infection. My current project “Cross-talk between inflammation and autophagy in tuberculosis” is supported by the European H2020 Marie Skɫodowska-Curie Intra-European Fellowship program (H200-MSCA-IF-2014 - 655424 - INFLAMMAFISH).

More information about Mónica Varela Álvarez

Brief Biography

  • 2016 – present: Postdoctoral fellow (Marie Curie IF), Institute of Biology, University of Leiden, The Netherlands. Supervisor: Prof. Annemarie Meijer

  • 2010 – 2015: PhD student (JaePredoc Fellow), Immunology and Genomics Group, Marine Research Institute (IIM-CSIC), Vigo, Spain. Promotor: Prof. Dr. Novoa and Prof. Dr. Figueras.

  • 2008 – 2010: MSc research intern, Department of Cell Biology, Santiago de Compostela University (USC), Santiago de Compostela, Spain. Supervisor: Prof. Dr. Lamas.

  • 2007 -2008: BSc research intern, Department of Cell Biology, Santiago de Compostela University (USC), Santiago de Compostela, Spain. Supervisor: Prof. Dr. Lamas.

Research

My research focuses on the study of host-pathogen interaction using larval zebrafish as a model of bacterial infection. My current project “Cross-talk between inflammation and autophagy in tuberculosis” is supported by the European H2020 Marie Skɫodowska-Curie Intra-European Fellowship program (H200-MSCA-IF-2014 - 655424 - INFLAMMAFISH).

The increasing occurrence of multidrug-resistant Mycobacterium tuberculosis strains makes tuberculosis (TB) a key priority for infectious disease research. Inflammation and autophagy are two fundamental processes critical to TB pathogenesis. Accumulating evidence shows that TB disease is worsened by deregulation of the inflammatory response. On the other hand, autophagy has recently emerged as a crucial host defence mechanism. Autophagy counteracts the ability of mycobacteria to survive inside host cells and targets them for degradation. Autophagy is also thought to control the inflammatory response. However, the interaction between inflammation and autophagy in host defence against TB remains unclear. The aim of my current project is to use the well-established zebrafish model of TB to gain insight into this key question.

Postdoc / Marie Curie fellow

  • Wiskunde en Natuurwetenschappen
  • Instituut Biologie Leiden
  • IBL Animal Sciences & Health

Work address

Gorlaeus Building
Einsteinweg 55
2333 CC Leiden
Room number GW3.29

Contact

Postdoc / guest

  • Wiskunde en Natuurwetenschappen
  • Instituut Biologie Leiden
  • IBL Animal Sciences & Health

Work address

Sylvius
Sylviusweg 72
2333 BE Leiden

Contact

Publications

  • Geen relevante nevenwerkzaamheden

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