Marcellus Ubbink studies the relation between evolution, structure, dynamics and function of enzymes, with a particular interest in beta-lactamases. He uses a range of biophysical techniques for this purpose.

More information about Marcellus Ubbink

Curriculum Vitae

Personal information

Nationality:   Dutch
Year of birth:   1965

Education

1994   PhD, Leiden Institute of Chemistry, Leiden University, The Netherlands, 19 May 1994 (cum laude)
Thesis title: ‘Cytochrome c-550 and the MADH redox chain from Thiobacillus versutus’
Advisor: Prof. Dr. G.W. Canters
1989   MSc in Biology, Faculty of Biology, Utrecht University, The Netherlands (cum laude)

Current and previous research positions

2022 – now    Scientific Director of the Leiden Institute of Chemistry
2019 – 2022   Director of Studies of the Leiden/Delft Bachelor Life Science and Technology
2010 – now     Full professor in Protein Chemistry, Leiden, Institute of Chemistry, Leiden University
2004 – 2010   Associate Professor, Leiden Institute of Chemistry, Leiden University, The Netherlands
1997 – 2003   Assistant Professor, Leiden Institute of Chemistry, Leiden University,
1994 – 1997   Postdoctoral Research Associate at Dept. Biochemistry, Cambridge University (UK)
1994                  Postdoctoral project (six months) at the laboratories of Dr. A. Pastore (EMBL, Heidelberg, Germany) and Dr. J. van der Oost (VU University, Amsterdam, The Netherlands)

Grants, awards, recognitions since 2012

2020  ENW-Klein grant (k€ 341)
2018   TTW Open technology grant (k€ 800)
2017   NWO-CW ECHO grant (k€ 260)
2016   NWO-CW ECHO grant (k€ 260)
2014   NWO-CW KIEM project (k€ 19)
2013   NWO-CW ECHO grant (k€ 260)
2013   NWO NMARRS Graduate School programme with H.J.M. de Groot (k€ 200)
2012   NWO Groot for Paramagnetic NMR Facility (k€ 2,163)
2012   EU Marie Curie ITN “paramagnetic NMR (pNMR)”, (co-applicant k€ 244)
2012   ESF funding International Conference on Molecular Aspects of Protein-Protein Interactions (k€ 30)
2012   Co-applicant of the grant for an ultra-high field NMR facility for the Netherlands (uNMR-NL) from the National Roadmap Program for Large Research Infrastructures (k€ 18,500)

Contribution to teaching and supervision

Current: Undergraduate course Biochemistry 1 for 1st years students Life Science and Technology. Graduate course Enzyme Dynamics. Bachelor course Anthropocene in the minor Sustainable Chemistry and Biotechnology (with Dr. Hetterscheid).

Supervision as promotor: 28 PhD students (2010-2023), as co-promotor: 10 PhD students (1998-2010).

Other responsibilities since 2010

• Editorial Board member for Emerging Topics in Life Sciences (since 2016)
• Secretary of the Netherlands Society for Biochemistry and Molecular Biology (NVBMB, 2008-2012)
• Board member of the Netherlands Magnetic Resonance Research School (since 2015)
• Member, Secretary and Chair of the board of the NWO Proteins Study Group (2013-2015)
• Chair of the organising committee for the Lorentz Workshop ‘Proteins and Beyond’, Leiden (2014)
• Member of the scientific committee of the 2nd and 3rd International Conference on Molecular Aspects of Protein-Protein Interactions (2007, 2010)
• Chair of the 4th IC on Molecular Aspects of Protein-Protein Interactions, Poland (2012)
• Chair of the ESF-EMAR workshop “Paramagnetic tagging in NMR”, Spain (2010)
• Member of the organising committee of the FEBS workshops Trends in Transient Interactions between Biological Macromolecules (2005, 2007, 2010)
• Representative of the Faculty in the Program Board of the Medical Delta Organisation (2012-2016)
• Organiser of the Annual Institute’s Research Symposium (with Prof. Koper, since 2011)
• Member (2010-2013) and chair (2014-2016) C.J. Kok committee to select best Science thesis within the Faculty
• Member of the Faculty Council (2011-2019)

Publication record including five recent representative publications

Ca. 160 papers with >5000 citations, H-index 43 (Google Scholar)

Full publication record: ResearcherID, or Leiden University

Publications

Activities