Leendert 't Hart
- Name
- Dr. L.M. 't Hart
- Telephone
- +31 71 526 9111
- l.m.t_hart@lumc.nl
- ORCID iD
- 0000-0003-4401-2938
- Faculteit Geneeskunde
- Divisie 4
- Cel en Chemische biologie
- Allesoe, R.L.; Lundgaard, A.T.; Medina, R.H.; Aguayo-Orozco, A.; Johansen, J.; Nissen, J.N.; Brorsson, C.; Mazzoni, G.; Niu, L.L.; Biel, J.H.; Brasas, V.; Webel, H.; Benros, M.E.; Pedersen, A.G.; Chmura, P.J.; Jacobsen, U.P.; Mari, A.; Koivula, R.; Mahajan, A.; Vinuela, A.; Tajes, J.F.; Sharma, S.; Haid, M.; Hong, M.G.; Musholt, P.B.; Masi, F. de; Vogt, J.; Pedersen, H.K.; Gudmundsdottir, V.; Jones, A.; Kennedy, G.; Bell, J.; Thomas, E.L.; Frost, G.; Thomsen, H.; Hansen, E.; Hansen, T.H.; Vestergaard, H.; Muilwijk, M.; Blom, M.T.; Hart, L.M.T.; Pattou, F.; Raverdy, V.; Brage, S.; Kokkola, T.; Heggie, A.; McEvoy, D.; Mourby, M.; Kaye, J.; Hattersley, A.; McDonald, T.; Ridderstrale, M.; Walker, M.; Forgie, I.; Giordano, G.N.; Pavo, I.; Ruetten, H.; Pedersen, O.; Hansen, T.; Dermitzakis, E.; Franks, P.W.; Schwenk, J.M.; Adamski, J.; McCarthy, M.I.; Pearson, E.; Banasik, K.; Rasmussen, S.; Brunak, S. & IMI DIRECT Consortium (2023), Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models, Nature Biotechnology 41.
- Dawed, A.Y.; Mari, A.; Brown, A.; McDonald, T.J.; Li, L.; Wang, S.C.; Hong, M.G.; Sharma, S.; Robertson, N.R.; Mahajan, A.; Wang, X.; Walker, M.; Gough, S.; Hart, L.M.'.; Zhou, K.X.; Forgie, I.; Ruetten, H.; Pavo, I.; Bhatnagar, P.; Jones, A.G.; Pearson, E.R. & DIRECT consortium (2023), Pharmacogenomics of GLP-1 receptor agonists, The Lancet Diabetes & Endocrinology 11(1): 33-41.
- Kanoni, S.; Graham, S.E.; Wang, Y.X.; Surakka, I.; Ramdas, S.; Zhu, X.; Clarke, S.L.; Bhatti, K.F.; Vedantam, S.; Winkler, T.W.; Locke, A.E.; Marouli, E.; Zajac, G.J.M.; Wu, K.H.H.; Ntalla, I.; Hui, Q.; Klarin, D.; Hilliard, A.T.; Wang, Z.Y.; Xue, C.; Thorleifsson, G.; Helgadottir, A.; Gudbjartsson, D.F.; Holm, H.; Olafsson, I.; Hwang, M.Y.; Han, S.; Akiyama, M.; Sakaue, S.; Terao, C.; Kanai, M.; Zhou, W.; Brumpton, B.; Rasheed, H.; Havulinna, A.S.; Veturi, Y.; Pacheco, J.A.; Rosenthal, E.A.; Lingren, T.; Feng, Q.P.; Kullo, I.J.; Narita, A.; Takayama, J.; Martin, H.C.; Hunt, K.A.; Trivedi, B.; Haessler, J.; Giulianini, F.; Bradford, Y.; Miller, J.E.; Campbell, A.; Lin, K.; Millwood, I.Y.; Rasheed, A.; Hindy, G.; Faul, J.D.; Zhao, W.; Weir, D.R.; Turman, C.; Huang, H.Y.; Graf, M.; Choudhury, A.; Sengupta, D.; Mahajan, A.; Brown, M.R.; Zhang, W.H.; Yu, K.T.; Schmidt, E.M.; Pandit, A.; Gustafsson, S.; Yin, X.Y.; Luan, J.A.; Zhao, J.H.; Matsuda, F.; Jang, H.M.; Yoon, K.; Medina-Gomez, C.; Pitsillides, A.; Hottenga, J.J.; Wood, A.R.; Ji, Y.J.; Gao, Z.S.; Haworth, S.; Yousri, N.A.; Mitchell, R.E.; Chai, J.F.; Aadahl, M.; Bjerregaard, A.A.; Yao, J.; Manichaikul, A.; Hwu, C.M.; Hung, Y.J.; Warren, H.R.; Ramirez, J.; Bork-Jensen, J.; Karhus, L.L.; Goel, A.; Sabater-Lleal, M.; Noordam, R.; Mauro, P.; Matteo, F.; McDaid, A.F.; Marques-Vidal, P.; Wielscher, M.; Trompet, S.; Sattar, N.; Mollehave, L.T.; Munz, M.; Zeng, L.Y.; Huang, J.F.; Yang, B.; Poveda, A.; Kurbasic, A.; Lamina, C.; Forer, L.; Scholz, M.; Galesloot, T.E.; Bradfeld, J.P.; Ruotsalainen, S.E.; Daw, E.; Zmuda, J.M.; Mitchell, J.S.; Fuchsberger, C.; Christensen, H.; Brody, J.A.; Vazquez-Moreno, M.; Feitosa, M.F.; Wojczynski, M.K.; Wang, Z.; Preuss, M.H.; Mangino, M.; Christofdou, P.; Verweij, N.; Benjamins, J.W.; Engmann, J.; Tsao, N.L.; Verma, A.; Slieker, R.C.; , K.S. lo; Zilhao, N.R.; , P. le; Kleber, M.E.; Delgado, G.E.; Huo, S.F.; Ikeda, D.D.; Iha, H.; Yang, J.; Liu, J.; Leonard, H.L.; Marten, J.; Frank, M.; Schmidt, B.; Smyth, L.J.; Canadas-Garre, M.; Wang, C.L.; Nakatochi, M.; Wong, A.; Hutri-Kahonen, N.; Sim, X.L.; Xia, R.; Huerta-Chagoya, A.; Fernandez-Lopez, J.C.; Lyssenko, V.; Nongmaithem, S.S.; Bayyana, S.; Stringham, H.M.; Irvin, M.R.; Oldmeadow, C.; Kim, H.N.; Ryu, S.; Timmers, P.R.H.J.; Arbeeva, L.; Dorajoo, R.; Lange, L.A.; Prasad, G.; Lores-Motta, L.; Pauper, M.; Long, J.R.; Li, X.H.; Theusch, E.; Takeuchi, F.; Spracklen, C.N.; Loukola, A.; Bollepalli, S.; Warner, S.C.; Wang, Y.X.; Wei, W.B.; Nutile, T.; Ruggiero, D.; Sung, Y.J.; Chen, S.F.; Liu, F.C.; Yang, J.Y.; Kentistou, K.A.; Banas, B.; Nardone, G.G.; Meidtner, K.; Bielak, L.F.; Smith, J.A.; Hebbar, P.; Farmaki, A.E.; Hofer, E.; Lin, M.X.; Concas, M.P.; Vaccargiu, S.; Most, P.J. van der; Pitkanen, N.; Cade, B.E.; Laan, S.W. van der; Chitrala, K.N.; Weiss, S.; Bentley, A.R.; Doumatey, A.P.; Adeyemo, A.A.; Lee, J.Y.; Petersen, E.R.B.; Nielsen, A.A.; Choi, H.S.; Nethander, M.; Freitag-Wolf, S.; Southam, L.; Rayner, N.W.; Wang, C.A.; Lin, S.Y.; Wang, J.S.; Couture, C.; Lyytikainen, L.P.; Nikus, K.; Cuellar-Partida, G.; Vestergaard, H.; Hidalgo, B.; Giannakopoulou, O.; Cai, Q.Y.; Obura, M.O.; Setten, J. van; Li, X.Y.; Liang, J.J.; Tang, H.; Terzikhan, N.; Shin, J.H.; Jackson, R.D.; Reiner, A.P.; Martin, L.W.; Chen, Z.M.; Li, L.M.; Kawaguchi, T.; Thiery, J.; Bis, J.C.; Launer, L.J.; Li, H.X.; Nalls, M.A.; Raitakari, O.T.; Ichihara, S.; Wild, S.H.; Nelson, C.P.; Campbell, H.; Jager, S.; Nabika, T.; Al-Mulla, F.; Niinikoski, H.; Braund, P.S.; Kolcic, I.; Kovacs, P.; Giardoglou, T.; Katsuya, T.; Kleijn, D. de; Borst, G.J. de; Kim, E.K.; Adams, H.H.H.; Ikram, M.A.; Zhu, X.F.; Asselbergs, F.W.; Kraaijeveld, A.O.; Beulens, J.W.J.; Shu, X.O.; Rallidis, L.S.; Pedersen, O.; Hansen, T.; Mitchell, P.; Hewitt, A.W.; Kahonen, M.; Perusse, L.; Bouchard, C.; Tonjes, A.; Chen, Y.D.I.; Pennell, C.E.; Mori, T.A.; Lieb, W.; Franke, A.; Ohlsson, C.; Mellstrom, D.; Cho, Y.S. & Lee, (2022), Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis, Genome Biology 23(1).
- Ramdas, S.; Judd, J.; Graham, S.E.; Kanoni, S.; Wang, Y.X.; Surakka, I.; Wenz, B.; Clarke, S.L.; Chesi, A.; Wells, A.; Bhatti, K.F.; Vedantam, S.; Winkler, T.W.; Locke, A.E.; Marouli, E.; Zajac, G.J.M.; Wu, K.H.H.; Ntalla, I.; Hui, Q.; Klarin, D.; Hilliard, A.T.; Wang, Z.Y.; Xue, C.; Thorleifsson, G.; Helgadottir, A.; Gudbjartsson, D.F.; Holm, H.; Olafsson, I.; Hwang, M.Y.; Han, S.; Akiyama, M.; Sakaue, S.; Terao, C.; Kanai, M.; Zhou, W.; Brumpton, B.; Rasheed, H.; Havulinna, A.S.; Veturi, Y.; Pacheco, J.A.; Rosenthal, E.A.; Lingren, T.; Feng, Q.P.; Kullo, I.J.; Narita, A.; Takayama, J.; Martin, H.C.; Hunt, K.A.; Trivedi, B.; Haessler, J.; Giulianini, F.; Bradford, Y.; Miller, J.E.; Campbell, A.; Lin, K.; Millwood, I.Y.; Rasheed, A.; Hindy, G.; Faul, J.D.; Zhao, W.; Weir, D.R.; Turman, C.; Huang, H.Y.; Graff, M.; Choudhury, A.; Sengupta, D.; Mahajan, A.; Brown, M.R.; Zhang, W.H.; Yu, K.T.; Schmidt, E.M.; Pandit, A.; Gustafsson, S.; Yin, X.Y.; Luan, J.A.; Zhao, J.H.; Matsuda, F.; Jang, H.M.; Yoon, K.; Medina-Gomez, C.; Pitsillides, A.; Hottenga, J.J.; Wood, A.R.; Ji, Y.J.; Gao, Z.S.; Haworth, S.; Mitchell, R.E.; Chai, J.F.; Aadahl, M.; Bjerregaard, A.A.; Yao, J.; Manichaikul, A.; Lee, W.J.; Hsiung, C.A.; Warren, H.R.; Ramirez, J.; Bork-Jensen, J.; Karhus, L.L.; Goel, A.; Sabater-Lleal, M.; Noordam, R.; Mauro, P.; Matteo, F.; McDaid, A.F.; Marques-Vidal, P.; Wielscher, M.; Trompet, S.; Sattar, N.; Mollehave, L.T.; Munz, M.; Zeng, L.Y.; Huang, J.F.; Yang, B.; Poveda, A.; Kurbasic, A.; Schonherr, S.; Forer, L.; Scholz, M.; Galesloot, T.E.; Bradfield, J.P.; Ruotsalainen, S.E.; Daw, E.W.; Zmuda, J.M.; Mitchell, J.S.; Fuchsberger, C.; Christensen, H.; Brody, J.A.; , P. le; Feitosa, M.F.; Wojczynski, M.K.; Hemerich, D.; Preuss, M.; Mangino, M.; Christofidou, P.; Verweij, N.; Benjamins, J.W.; Engmann, J.; Noah, T.L.; Verma, A.; Slieker, R.C.; , K.S. lo; Zilhao, N.R.; Kleber, M.E.; Delgado, G.E.; Huo, S.F.; Ikeda, D.D.; Iha, H.; Yang, J.; Liu, J.; Demirkan, A.; Leonard, H.L.; Marten, J.; Emmel, C.; Schmidt, B.; Smyth, L.J.; Canadas-Garre, M.; Wang, C.L.; Nakatochi, M.; Wong, A.; Hutri-Kahonen, N.; Sim, X.L.; Xia, R.; Huerta-Chagoya, A.; Fernandez-Lopez, J.C.; Lyssenko, V.; Nongmaithem, S.S.; Sankareswaran, A.; Irvin, M.R.; Oldmeadow, C.; Kim, H.N.; Ryu, S.; Timmers, P.R.H.J.; Arbeeva, L.; Dorajoo, R.; Lange, L.A.; Prasad, G.; Lores-Motta, L.; Pauper, M.; Long, J.R.; Li, X.H.; Theusch, E.; Takeuchi, F.; Spracklen, C.N.; Loukola, A.; Bollepalli, S.; Warner, S.C.; Wang, Y.X.; Wei, W.B.; Nutile, T.; Ruggiero, D.; Sung, Y.J.; Chen, S.F.; Liu, F.C.; Yang, J.Y.; Kentistou, K.A.; Banas, B.; Morgan, A.; Meidtner, K.; Bielak, L.F.; Smith, J.A.; Hebbar, P.; Farmaki, A.E.; Hofer, E.; Lin, M.X.; Concas, M.P.; Vaccargiu, S.; Most, P.J. van der; Pitkanen, N.; Cade, B.E.; Laan, S.W. van der; Chitrala, K.N.; Weiss, S.; Bentley, A.R.; Doumatey, A.P.; Adeyemo, A.A.; Lee, J.Y.; Petersen, E.R.B.; Nielsen, A.A.; Choi, H.S.; Nethander, M.; Freitag-Wolf, S.; Southam, L.; Rayner, N.W.; Wang, C.A.; Lin, S.Y.; Wang, J.S.; Couture, C.; Lyytikainen, L.P.; Nikus, K.; Cuellar-Partida, G.; Vestergaard, H.; Hidalgo, B.; Giannakopoulou, O.; Cai, Q.Y.; Obura, M.O.; Setten, J. van; He, K.Y.; Tang, H.; Terzikhan, N.; Shin, J.H.; Jackson, R.D.; Reiner, A.P.; Martin, L.W.; Chen, Z.M.; Li, L.M.; Kawaguchi, T.; Thiery, J.; Bis, J.C.; Launer, L.J.; Li, H.X.; Nalls, M.A.; Raitakari, O.T.; Ichihara, S.; Wild, S.H.; Nelson, C.P.; Campbell, H.; Jager, S.; Nabika, T.; Al-Mulla, F.; Niinikoski, H.; Braund, P.S.; Kolcic, I.; Kovacs, P.; Giardoglou, T.; Katsuya, T.; Kleijn, D. de; Borst, G.J. de; Kim, E.K.; Adams, H.H.H.; Ikram, M.A.; Zhu, X.F.; Asselbergs, F.W.; Kraaijeveld, A.O.; Beulens, J.W.J.; Shu, X.O.; Rallidis, L.S.; Pedersen, O.; Hansen, T.; Mitchell, P.; Hewitt, A.W.; Kahonen, M.; Perusse, L.; Bouchard, C.; Tonjes, A.; Chen, Y.D.I.; Pennell, C.E.; Mori, T.A.; Lieb, W.; Franke, A.; Ohlsson, C.; Mellstrom, D.; Cho, Y.S. & Lee, H. (2022), A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids, American Journal of Human Genetics 109(8): 1366-1387.
- Wang, W.Y.; Luo, J.; Dijk, K.W. van; Hagg, S.; Grassmann, F.; Hart, L.M. 't; Heemst, D. van & Noordam, R. (2022), Assessment of the bi-directional relationship between blood mitochondrial DNA copy number and type 2 diabetes mellitus, Diabetologia 65.
- Bouland, G.A.; Beulens, J.W.J.; Nap, J.; Slik, A.R. van der; Zaldumbide, A.; Hart, L.M. 't & Slieker, R.C. (2022), Diabetes risk loci-associated pathways are shared across metabolic tissues, BMC Genomics 23(1).
- Dawed, A.Y.; Yee, S.W.; Zhou, K.X.; Leeuwen, N. van; Zhang, Y.F.; Siddiqui, M.K.; Etheridge, A.; Innocenti, F.; Xu, F.; Li, J.H.; Beulens, J.W.; Heijden, A.A. van der; Slieker, R.C.; Chang, Y.C.; Mercader, J.M.; Kaur, V.; Witte, J.S.; Lee, M.T.M.; Kamatani, Y.; Momozawa, Y.; Kubo, M.; Palmer, C.N.A.; Florez, J.C.; Hedderson, M.M.; Hart, L.M. 't; Giacomini, K.M.; Pearson, E.R. & MetGen Plus DIRECT Consortium (2022), Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682.
- Wesolowska-Andersen, A.; Brorsson, C.A.; Bizzotto, R.; Mari, A.; Tura, A.; Koivula, R.; Mahajan, A.; Vinuela, A.; Tajes, J.F.; Sharma, S.; Haid, M.; Prehn, C.; Artati, A.; Hong, M.G.; Musholt, P.B.; Kurbasic, A.; Masi, F. de; Tsirigos, K.; Pedersen, H.K.; Gudmundsdottir, V.; Thomas, C.E.; Banasik, K.; Jennison, C.; Jones, A.; Kennedy, G.; Bell, J.; Thomas, L.; Frost, G.; Thomsen, H.; Allin, K.; Hansen, T.H.; Vestergaard, H.; Hansen, T.; Rutters, F.; Elders, P.; T'Hart, L.; Bonnefond, A.; Canouil, M.; Brage, S.; Kokkola, T.; Heggie, A.; McEvoy, D.; Hattersley, A.; McDonald, T.; Teare, H.; Ridderstrale, M.; Walker, M.; Forgie, I.; Giordano, G.N.; Froguel, P.; Pavo, I.; Ruetten, H.; Pedersen, O.; Dermitzakis, E.; Franks, P.W.; Schwenk, J.M.; Adamski, J.; Pearson, E.; McCarthy, M.I. & Brunak, S. (2022), Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals, Cell Reports Medicine 3(1).
- Graham, S.E.; Clarke, S.L.; Wu, K.H.H.; Kanoni, S.; Zajac, G.J.M.; Ramdas, S.; Surakka, I.; Ntalla, I.; Vedantam, S.; Winkler, T.W.; Locke, A.E.; Marouli, E.; Hwang, M.Y.; Han, S.; Narita, A.; Choudhury, A.; Bentley, A.R.; Ekoru, K.; Verma, A.; Trivedi, B.; Martin, H.C.; Hunt, K.A.; Hui, Q.; Klarin, D.; Zhu, X.; Thorleifsson, G.; Helgadottir, A.; Gudbjartsson, D.F.; Holm, H.; Olafsson, I.; Akiyama, M.; Sakaue, S.; Terao, C.; Kanai, M.; Zhou, W.; Brumpton, B.; Rasheed, H.; Ruotsalainen, S.E.; Havulinna, A.S.; Veturi, Y.; Feng, Q.P.; Rosenthal, E.A.; Lingren, T.; Pacheco, J.A.; Pendergrass, S.A.; Haessler, J.; Giulianini, F.; Bradford, Y.; Miller, J.E.; Campbell, A.; Lin, K.; Millwood, I.Y.; Hindy, G.; Rasheed, A.; Faul, J.D.; Zhao, W.; Weir, D.R.; Turman, C.; Huang, H.Y.; Graff, M.; Mahajan, A.; Brown, M.R.; Zhang, W.H.; Yu, K.T.; Schmidt, E.M.; Pandit, A.; Gustafsson, S.; Yin, X.Y.; Luan, J.A.; Zhao, J.H.; Matsuda, F.; Jang, H.M.; Yoon, K.; Medina-Gomez, C.; Pitsillides, A.; Hottenga, J.J.; Willemsen, G.; Wood, A.R.; Ji, Y.J.; Gao, Z.S.; Haworth, S.; Mitchell, R.E.; Chai, J.F.; Aadahl, M.; Yao, J.; Manichaikul, A.; Warren, H.R.; Ramirez, J.; Bork-Jensen, J.; Karhus, L.L.; Goel, A.; Sabater-Lleal, M.; Noordam, R.; Sidore, C.; Fiorillo, E.; McDaid, A.F.; Marques-Vidal, P.; Wielscher, M.; Trompet, S.; Sattar, N.; Mollehave, L.T.; Thuesen, B.H.; Munz, M.; Zeng, L.Y.; Huang, J.F.; Yang, B.; Poveda, A.; Kurbasic, A.; Lamina, C.; Forer, L.; Scholz, M.; Galesloot, T.E.; Bradfield, J.P.; Daw, E.W.; Zmuda, J.M.; Mitchell, J.S.; Fuchsberger, C.; Christensen, H.; Brody, J.A.; Feitosa, M.F.; Wojczynski, M.K.; Preuss, M.; Mangino, M.; Christofidou, P.; Verweij, N.; Benjamins, J.W.; Engmann, J.; Kember, R.L.; Slieker, R.C.; , K.S. lo; Zilhao, N.R.; , P. le; Kleber, M.E.; Delgado, G.E.; Huo, S.; Ikeda, D.D.; Iha, H.; Yang, J.; Liu, J.; Leonard, H.L.; Marten, J.; Schmidt, B.; Arendt, M.; Smyth, L.J.; Canadas-Garre, M.; Wang, C.L.; Nakatochi, M.; Wong, A.; Hutri-Kahonen, N.; Sim, X.L.; Xia, R.; Huerta-Chagoya, A.; Fernandez-Lopez, J.C.; Lyssenko, V.; Ahmed, M.; Jackson, A.U.; Irvin, M.R.; Oldmeadow, C.; Kim, H.N.; Ryu, S.; Timmers, P.R.H.J.; Arbeeva, L.; Dorajoo, R.; Lange, L.A.; Chai, X.R.; Prasad, G.; Lores-Motta, L.; Pauper, M.; Long, J.R.; Li, X.H.; Theusch, E.; Takeuchi, F.; Spracklen, C.N.; Loukola, A.; Bollepalli, S.; Warner, S.C.; Wang, Y.X.; Wei, W.B.; Nutile, T.; Ruggiero, D.; Sung, Y.J.; Hung, Y.J.; Chen, S.F.; Liu, F.C.; Yang, J.Y.; Kentistou, K.A.; Gorski, M.; Brumat, M.; Meidtner, K.; Bielak, L.F.; Smith, J.A.; Hebbar, P.; Farmaki, A.E.; Hofer, E.; Lin, M.X.; Xue, C.; Zhang, J.F.; Concas, M.P.; Vaccargiu, S.; Most, P.J. van der; Pitkanen, N.; Cade, B.E.; Lee, J.; Laan, S.W. van der; Chitrala, K.N.; Weiss, S.; Zimmermann, M.E.; Lee, J.Y.; Choi, H.S.; Nethander, M.; Freitag-Wolf, S.; Southam, L.; Rayner, N.W.; Wang, C.A.; Lin, S.Y.; Wang, J.S.; Couture, C.; Lyytikainen, L.P.; Nikus, K.; Cuellar-Partida, G.; Vestergaard, H.; Hildalgo, B.; Giannakopoulou, O.; Cai, Q.Y.; Obura, M.O.; Setten, J. van; Li, X.Y.; Schwander, K.; Terzikhan, N.; Shin, J.H.; Jackson, R.D.; Reiner, A.P.; Martin, L.W.; Chen, Z.M.; Li, L.M.; Highland, H.M.; Young, K.L.; Kawaguchi, T.; Thiery, J.; Bis, J.C.; Nadkarni, G.N.; Launer, L.J.; Li, H.X.; Nalls, M.A.; Raitakari, O.T.; Ichihara, S.; Wild, S.H.; Nelson, C.P.; Campbell, H.; Jager, S.; Nabika, T.; Al-Mulla, F.; Niinikoski, H.; Braund, P.S.; Kolcic, I.; Kovacs, P.; Giardoglou, T.; Katsuya, T.; Bhatti, F.; Kleijn, D. de; Borst, G.J. de; Kim, E.K.; Adams, H.H.H.; Ikram, M.A.; Zhu, X.F.; Asselbergs, F.W.; Kraaijeveld, A.O.; Beulens, J.W.J.; Shu, X.O.; Rallidis, L.S.; Pedersen, O.; Hansen, T.; Mitchell, P.; Hewitt, A.W.; Kahonen, M.; Perusse, L.; Bouchard, C.; Tonjes, A.; Chen, Y.D.I.; Pennell, C.E.; Mori, T.A.; Lieb, W.; Franke, A.; Ohlsson, C.; Mellstrom, D.; Cho, Y.S.; Lee, H.; Yuan, J.M.; Koh, W.P.; Rhee, S.Y.; Woo, J.T.; Heid, I.M.; Stark, K.J.; Volzke, H. & Ho (2021), The power of genetic diversity in genome-wide association studies of lipids, Nature 600(7890): 675-+.
- Slieker, R.C.; Donnelly, L.A.; Fitipaldi, H.; Bouland, G.A.; Giordano, G.N.; Akerlund, M.; Gerl, M.J.; Ahlqvist, E.; Ali, A.; Dragan, I.; Elders, P.; Festa, A.; Hansen, M.K.; Heijden, A.A. van der; Aly, D.M.; Kim, M.; Kuznetsov, D.; Mehl, F.; Klose, C.; Simons, K.; Pavo, I.; Pullen, T.J.; Suvitaival, T.; Wretlind, A.; Rossing, P.; Lyssenko, V.; Quigley, C.L.; Groop, L.; Thorens, B.; Franks, P.W.; Ibberson, M.; Rutter, G.A.; Beulens, J.W.J.; Hart, L.M. 't & Pearson, E.R. (2021), Distinct molecular signatures of clinical clusters in people with type 2 diabetes, Diabetes 70(11): 2683-2693.
- Thomaidou, S.; Slieker, R.C.; Slik, A.R. van der; Boom, J.; Mulder, F.; Munoz-Garcia, A.; Hart, L.M. 't; Koeleman, B.; Carlotti, F.; Hoeben, R.C.; Roep, B.O.; Mei, H.L. & Zaldumbide, A. (2021), Long RNA sequencing and ribosome profiling of inflamed beta-cells reveal an extensive translatome landscape, Diabetes 70(10): 2299-2312.
- Memarian, E.; Hart, L.M. 't; Slieker, R.C.; Lemmers, R.F.L.; Heijden, A.A. van der; Rutters, F.; Nijpels, G.; Schoep, E.; Lieverse, A.G.; Sijbrands, E.J.G.; Wuhrer, M.; Hoek, M. van & Dotz, V. (2021), Plasma protein N-glycosylation is associated with cardiovascular disease, nephropathy, and retinopathy in type 2 diabetes, BMJ Open Diabetes Research and Care 9(1).
- Slieker, R.C.; Heijden, A.A.W.A. van der; Siddiqui, M.K.; Langendoen-Gort, M.; Nijpels, G.; Herings, R.; Feenstra, T.L.; Moons, K.G.M.; Bell, S.; Elders, P.J.; Hart, L.M. 't & Beulens, J.W.J. (2021), Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study, BRITISH MEDICAL JOURNAL 374.
- Slieker, R.C.; Donnelly, L.A.; Fitipaldi, H.; Bouland, G.A.; Giordano, G.N.; Akerlund, M.; Gerl, M.J.; Ahlqvist, E.; Ali, A.; Dragan, I.; Festa, A.; Hansen, M.K.; Aly, D.M.; Kim, M.; Kuznetsov, D.; Mehl, F.; Klose, C.; Simons, K.; Pavo, I.; Pullen, T.J.; Suvitaival, T.; Wretlind, A.; Rossing, P.; Lyssenko, V.; Legido-Quigley, C.; Groop, L.; Thorens, B.; Franks, P.W.; Ibberson, M.; Rutter, G.A.; Beulens, J.W.J.; Hart, L.M. 't & Pearson, E.R. (2021), Replication and cross-validation of type 2 diabetes subtypes based on clinical variables, Diabetologia 64(9): 1982-1989.
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- Reiling, E.; Jafar-Mohammadi, B.; van't Riet, E.; Weedon, M.N.; Vliet-Ostaptchouk, J.V. van; Hansen, T.; Saxena, R.; Haeften, T.W. van; Arp, P.A.; , S. das; Nijpels, G.; Groenewoud, M.J.; Hove, E.C. van; Uitterlinden, A.G.; Smit, J.W.A.; Morris, A.D.; Doney, A.S.F.; Palmer, C.N.A.; Guiducci, C.; Hattersley, A.T.; Frayling, T.M.; Pedersen, O.; Slagboom, P.E.; Altshuler, D.M.; Groop, L.; Romijn, J.A.; Maassen, J.A.; Hofker, M.H.; Dekker, J.M.; McCarthy, M.I. & Hart, L.M. 't (2010), Genetic association analysis of LARS2 with type 2 diabetes, Diabetologia 53(1): 103-110.
- Reiling, E.; Jafar-Mohammadi, B.; van't Riet, E.; Weedon, M.N.; Vliet-Ostaptchouk, J.V. van; Hansen, T.; Saxena, R.; Haeften, T.W. van; Arp, P.A.; , S. das; Nijpels, G.; Groenewoud, M.J.; Hove, E.C. van; Uitterlinden, A.G.; Smit, J.W.A.; Morris, A.D.; Doney, A.S.F.; Palmer, C.N.A.; Guiducci, C.; Hattersley, A.T.; Frayling, T.M.; Pedersen, O.; Slagboom, P.E.; Altshuler, D.M.; Groop, L.; Romijn, J.A.; Maassen, J.A.; Hofker, M.H.; Dekker, J.M.; McCarthy, M.I. & Hart, L.M. 't (2010), Genetic association analysis of LARS2 with type 2 diabetes., Diabetologia 53(1): 103-10.
- Simonis-Bik, A.M.; Nijpels, G.; Haeften, T.W. van; Houwing-Duistermaat, J.J.; Boomsma, D.I.; Reiling, E.; Hove, E.C. van; Diamant, M.; Kramer, M.H.H.; Heine, R.J.; Maassen, J.A.; Slagboom, P.E.; Willemsen, G.; Dekker, J.M.; Eekhoff, E.M.; Geus, E.J. de & Hart, L.M. 't (2010), Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic beta-Cell Function, Diabetes 59(1): 293-301.
- Gaens KHJ, Ferreira I, van der Kallen CJH, van Greevenbroek MMJ, Blaak EE, Feskens EJM, Dekker JM, Nijpels G, Heine RJ & 't Hart LM (2009), Association of Polymorphism in the Receptor for Advanced Glycation End Products (RAGE) Gene with Circulating RAGE Levels, Journal of Clinical Endocrinology and Metabolism 94(12): 5174-5180.
- Simonis-Bik AMC, Eekhoff EMW, de Moor MHM, Kramer MHH, Boomsma DI, Heine RJ, Dekker JM, Maassen JA, 't Hart LM & Diamant M (2009), Genetic influences on the insulin response of the beta cell to different secretagogues, Diabetologia 52(12): 2570-2577.
- Reiling E, van't Riet E, Groenewoud MJ, Welschen LMC, van Hove EC, Nijpels G, Maassen JA, Dekker JM & 't Hart LM (2009), Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk, Diabetologia 52(9): 1866-1870.
- Reiling E, van Vliet-Ostaptchouk JV, van't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC & Romijn JA (2009), Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study, European Journal of Human Genetics 17(8): 1056-1062.
- Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM & Dekker JM (2009), Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study., European Journal of Human Genetics 17(8): 1056-62.
- Jaakkola U, Kallio J, Heine RJ, Nijpels G, t'Hart LM, Maassen JA, Bouter LM, Stehouwer CDA & Dekker JM (2009), Neuropeptide Y polymorphism significantly magnifies diabetes and cardiovascular disease risk in obesity: the Hoorn Study, European Journal of Clinical Nutrition 63(1): 150-152.
- Groenewoud MJ, Dekker JM, Fritsche A, Reiling E, Nijpels G, Heine RJ, Maassen JA, Machicao F, Schafer SA, Haring HU, 't Hart LM & van Haeften TW (2008), Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps, Diabetologia 51(9).
- Schafer SA, Tschritter O, Machicao F, Thamer C, Stefan N, Gallwitz B, Holst JJ, Dekker JM, t'Hart LM, Nijpels G, van Haeften TW, Haring HU & Fritsche A (2007), Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms, Diabetologia 50(12).
- Maassen JA, 't Hart LM & Ouwens DM (2007), Lessons that can be learned from patients with diabetogenic mutations in mitochondrial DNA: Implications for common type 2 diabetes, Current Opinion in Clinical Nutrition and Metabolic Care 10(6).
- Maassen JA, Hart LM, Janssen GMC, Reiling E, Romijn JA & Lemkes HH (2006), Mitochondrial diabetes and its lessons for common Type 2 diabetes.
- Monraats PS, de Vries F, de Jong LW, Pons D, Sewgobind VDKD, Zwinderman AH, De Maat MPM, 't Hart LM, Doevendans PA, de Winter RJ, Tio RA, Waltenberger J, Frants RR, van der Laarse A, Van der Wall EE & Jukema JW (2006), Inflammation and apoptosis genes and the risk of restenosis after percutaneous coronary intervention, Pharmacogenetics and Genomics 16(10): 747-754.
- Hendrickx JJ, Mudde AH, t' Hart LM, Huygen PLM & Cremers CWRJ (2006), Progressive sensorineural hearing impairment in maternally inherited diabetes mellitus and deafness (MIDD), Otology and Neurotology 27(6).
- Maassen JA, Tafrechi RSJ, Janssen GMC, Raap AK, Lemkes HH & 't Hart LM (2006), New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome, Endocrinology and Metabolism Clinics of North America 35(2).
- Janssen GMC, Neu A, t'Hart LM, van de Sande CMT & Maassen JA (2006), Novel mitochondrial DNA length variants and genetic instability in a family with diabetes and deafness, Experimental and Clinical Endocrinology and Diabetes 114(4).
- Monraats PS, Pireso NMM, Schepers A, Agema WRP, Boesten LSM, de Vries MR, Zwinderman AH, de Maat MPM, Doevendans PAFM, de Winter RJ, Tio RA, Waltenberger J, 't Hart LM, Frants RR, Quax PHA, van Vlijmen BJM, Havekes LM, van der Laarse A, van der Wall EE & Jukema JW (2005), Tumor necrosis factor-alpha plays an important role in restenosis development, FASEB Journal 19(14).
- t Hart LM, Hansen T, Rietveld I, Dekker JM, Nijpels G, Janssen GMC, Arp PA, Uitterlinden AG, Jorgensen T, Borch-Johnsen K, Pols HAP, Pedersen O, van Duijn CM, Heine RJ & Maassen JA (2005), Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene, Diabetes 54(6).
- Maassen JA, Janssen GMC & 'T Hart LM (2005), Molecular mechanisms of mitochondrial diabetes (MIDD), Annals of Medicine 37(3).
- Stumvoll M, Fritsche A, t'Hart LM, Machann J, Thamer C, Tschritter O, Van Haeftens TW, Jacob S, Dekker JM, Maassen JA, Machicao F, Schick F, Heine RJ & Haring H (2004), The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations, Experimental and Clinical Endocrinology and Diabetes 112(5).
- t Hart LM, Fritsche A, Rietveld I, Dekker JM, Nijpels G, Machicao F, Stumvoll M, van Duijn CM, Haring HU, Heine RJ, Maassen JA & van Haeften TW (2004), Genetic factors and insulin secretion - Gene variants in the IGF genes, Diabetes 53.
- Maassen JA, 't Hart LM, van Essen E, Heine RJ, Nijpels G, Tafrechi RSJ, Raap AK, Janssen GMC & Lemkes HHPJ (2004), Mitochondrial diabetes - Molecular mechanisms and clinical presentation, Diabetes 53.
- 't Hart LM, Maassen JA, Dekker JM, Heine RJ & Maassen JA (2003), Lack of association between gene variants in the ALMS1 gene and Type 2 diabetes mellitus, Diabetologia 46(7).
- 't Hart LM, van Haeften TW, Dekker JM, Bot M, Heine RJ & Maassen JA (2002), Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 subunit of the ATP-sensitive K+ channel in the beta-cell, Diabetes 51(10).
- 't Hart LM, Nijpels G, Dekker JM, Maassen JA, Heine RJ & van Haeften TW (2002), Variations in insulin secretion in carriers of gene variants in IRS-1 and-2, Diabetes 51(3).
- van Essen EHR, Roep BO, 't Hart LM, Jansen JJ, Van den Ouweland JMW, Lemkes HHPJ & Maassen JA (2000), HLA-DQ polymorphism and degree of heteroplasmy of the A3243G mitochondrial DNA mutation in maternally inherited diabetes and deafness, Diabetic Medicine 17(12).