Krista van Meijgaarden
- Name
- K.E. van Meijgaarden
- Telephone
- +31 71 526 3800
- k.e.van.meijgaarden@umail.leidenuniv.nl
- Faculteit Geneeskunde
- Divisie 4
- Immunologie
- IHB HLA en ziekten
- Biesbroek, G.; Kapitein, B.; Kuipers, I.M.; Gruppen, M.P.; Stijn, D. van; Peros, T.E.; Veenendaal, M. van; Jansen, M.H.A.; Zee, C.W. van der; Kuip, M. van der; Asmuth, E.G.J. von; Mooij, M.G.; Boer, M.E.J. den; Landman, G.W.; Houten, M.A. van; Schonenberg-Meinema, D.; Furth, A.M.T. van; Hensbroek, M.B. van; Scherpbier, H.; Meijgaarden, K.E. van; Ottenhoff, T.H.M.; Joosten, S.A.; Ketharanathan, N.; Blink, M.; Brackel, C.L.H.; Zaaijer, H.L.; Hombrink, P.; Berg, J.M. van den; Buddingh, E.P. & Kuijpers, T.W. (2022), Inflammatory responses in SARS-CoV-2 associated Multisystem Inflammatory Syndrome and Kawasaki Disease in children: An observational study, PLoS ONE 17(11).
- Ruibal, P.; Franken, K.L.M.C.; Meijgaarden, K.E.V.; Wolfswinkel, M. van; Derksen, I.; Scheeren, F.A.; Janssen, G.M.C.; Veelen, P.A. van; Sarfas, C.; White, A.D.; Sharpe, S.A.; Palmieri, F.; Petrone, L.; Goletti, D.; Abeel, T.; Ottenhoff, T.H.M. & Joosten, S.A. (2022), Identification of HLA-E binding Mycobacterium tuberculosis-derived epitopes through improved prediction models, The Journal of Immunology 209(8): 1555-1565.
- Rakshit, S.; Adiga, V.; Ahmed, A.; Parthiban, C.; Kumar, N.C.; Dwarkanath, P.; Shivalingaiah, S.; Rao, S.S.; D'Souza, G.; Dias, M.; Maguire, T.J.A.; Doores, K.J.; Zoodsma, M.; Geckin, B.; Dasgupta, P.; Babji, S.; Meijgaarden, K.E. van; Joosten, S.J.; Ottenhoff, T.H.M.; Li, Y.; Netea, M.G.; Stuart, K.D.; Rosa, S.C. de; McElrath, M.J. & Vyakarnam, A. (2022), Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD (TM) vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults, Frontiers in Immunology 13.
- Uzorka, J.W.; Bakker, J.A.; Meijgaarden, K.E. van; Leyten, E.M.S.; Delfos, N.M.; Hetem, D.J.; Kerremans, J.; Zwarts, M.; Cozijn, S.; Ottenhoff, T.H.M.; Joosten, S.A. & Arend, S.M. (2022), Biomarkers to identify Mycobacterium tuberculosis infection among borderline QuantiFERON results, European Respiratory Journal 60(2).
- Pongracz, T.; Nouta, J.; Wang, W.J.; Meijgaarden, K.E. van; Linty, F.; Vidarsson, G.; Joosten, S.A.; Ottenhoff, T.H.M.; Hokke, C.H.; Vries, J.J.C. de; Arbous, S.M.; Roukens, A.H.E.; Wuhrer, M.; BEAT-COVID Grp & COVID-19 Grp (2022), Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19, EBioMedicine 78.
- Ruibal, P.; Franken, K.L.M.C.; Meijgaarden, K.E. van; Loon, J.J.F. van; Steen, D. van der; Heemskerk, M.H.M.; Ottenhoff, T.H.M. & Joosten, S.A. (2020), Peptide binding to HLA-E molecules in humans, nonhuman primates, and mice reveals unique binding peptides but remarkably conserved anchor residues, Journal of Immunology 205(10): 2861-2872.
- Coppola, M.; Villar-Hernandez, R.; Meijgaarden, K.E. van; Latorre, I.; Moreno, B.M.; Garcia-Garcia, E.; Franken, K.L.M.C.; Prat, C.; Stojanovic, Z.; Galvao, M.L.D.; Millet, J.P.; Sabria, J.; Sanchez-Montalva, A.; Noguera-Julian, A.; Geluk, A.; Dominguez, J. & Ottenhoff, T.H.M. (2020), Cell-mediated immune responses to in vivo-expressed and stage-specific mycobacterium tuberculosis antigens in latent and active tuberculosis across different age groups, Frontiers in Immunology 11.
- Dijkman, K.; Vervenne, R.A.W.; Sombroek, C.C.; Boot, C.; Hofman, S.O.; Meijgaarden, K.E. van; Ottenhoff, T.H.M.; Kocken, C.H.M.; Haanstra, K.G.; Vierboom, M.P.M. & Verreck, F.A.W. (2019), Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity, Frontiers in Immunology 10.
- Tanner, R.; Smith, S.G.; Meijgaarden, K.E. van; Giannoni, F.; Wilkie, M.; Gabriele, L.; Palma, C.; Dockrell, H.M.; Ottenhoff, T.H.M. & McShane, H. (2019), Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells, Journal of Immunological Methods 469: 1-10.
- Duffy, F.J.; Weiner, J.; Hansen, S.; Tabb, D.L.; Suliman, S.; Thompson, E.; Maertzdorf, J.; Shankar, S.; Tromp, G.; Parida, S.; Dover, D.; Axthelm, M.K.; Sutherland, J.S.; Dockrell, H.M.; Ottenhoff, T.H.M.; Scriba, T.J.; Picker, L.J.; Walzl, G.; Kaufmann, S.H.E.; Zak, D.E.; Kaufmann, S.H.E.; Parida, S.K.; Golinski, R.; Maertzdorf, J.; Weiner, J.; Jacobson, M.; McEwen, G.; Walzl, G.; Black, G.F.; Spuy, G. van der; Stanley, K.; Kriel, M.; Plessis, N. du; Nene, N.; Loxton, A.G.; Chegou, N.N.; Suliman, S.; Scriba, T.; Fisher, M.; Mahomed, H.; Hughes, J.; Downing, K.; Penn-Nicholson, A.; Mulenga, H.; Abel, B.; Bowmaker, M.; Kagina, B.; Kwong, W.; Hanekom, C.W.; Ottenhoff, T.H.M.; Klein, M.R.; Haks, M.C.; Ranken, K.L.F.; Geluk, A.; Meijgaarden, K.E. van; Joosten, S.A.; Baarle, D. van; Miedema, F.; Boom, W.H.; Thiel, B.; Sadoff, J.; Sizemore, D.; Ramachandran, S.; Barker, L.; Brennan, M.; Weichold, F.; Muller, S.; Geiter, L.; Schoolnik, G.; Dolganov, G.; , T. van; Mayanja-Kizza, H.; Joloba, M.; Zalwango, S.; Nsereko, M.; Okwera, B.; Kisingo, H.; Dockrell, H.M.; Smith, S.; Gorak-Stolinska, P.; Hur, Y.G.; Lalor, M.; Lee, J.S.; Crampin, A.C.; French, N.; Ngwira, B.; Smith, A.B.; Watkins, K.; Ambrose, L.; Simukonda, F.; Mvula, H.; Chilongo, F.; Saul, J.; Branson, K.; Kassa, D.; Abebe, A.; Mesele, T.; Tegbaru, B.; Howe, R.; Mihret, A.; Aseffa, A.; Bekele, Y.; Iwnetu, R.; Tafesse, M.; Yamuah, L.; Ota, M.; Sutherland, J.; Hill, P.; Adegbola, R.; Corrah, T.; Antonio, M.; Togun, T.; Adetifa, I.; Donkor, S.; Andersen, P.; Rosenkrands, I.; Doherty, M.; Weldingh, K. & GC6-74 Consortium (2019), Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome, Frontiers in Immunology 10.
- Meijgaarden, K.E. van; Khatri, B.; Smith, S.G.; Drittij, A.M.F.H.; Paus, R.A. de; Goeman, J.J.; Ho, M.M.; Dockrell, H.M.; McShane, H.; Joosten, S.A. & Ottenhoff, T.H.M. (2018), Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies, PLoS ONE 13(9).
- Bilsen, M.P.; Meijgaarden, K.E. van; Jong, H.K. de; Joosten, S.A.; Prins, C.; Kroft, L.J.M.; Jonker, J.T.; Crobach, S.; Pelger, R.C.; Ottenhoff, T.H.M. & Arend, S.M. (2018), A novel view on the pathogenesis of complications after intravesical BCG for bladder cancer, International Journal of Infectious Diseases 72: 63-68.
- Joosten, S.A.; Meijgaarden, K.E. van; Arend, S.M.; Prins, C.; Oftung, F.; Korsvold, G.E.; Kik, S.V.; Arts, R.J.W.; Crevel, R. van; Netea, M.G. & Ottenhoff, T.H.M. (2018), Mycobacterial growth inhibition is associated with trained innate immunity, Journal of Clinical Investigation 128(5): 1837-1851.
- Prezzemolo, T.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Caccamo, N.; Dieli, F.; Ottenhoff, T.H.M. & Joosten, S.A. (2018), Detailed characterization of human Mycobacterium tuberculosis specific HLA-E restricted CD8(+) T cells, European Journal of Immunology 48(2): 293-305.
- Coppola, M.; Arroyo, L.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Geluk, A.; Barrera, L.F. & Ottenhoff, T.H.M. (2017), Differences in IgG responses against infection phase related Mycobacterium tuberculosis (Mtb) specific antigens in individuals exposed or not to Mtb correlate with control of TB infection and progression, Tuberculosis 106: 25-32.
- Paus, R.A. de; Meijgaarden, K.E. van; Prins, C.; Kamphorst, M.H.; Arend, S.M.; Ottenhoff, T.H.M. & Joosten, S.A. (2017), Immunological characterization of latent tuberculosis infection in a low endemic country, Tuberculosis 106: 62-72.
- Rakshit, S.; Adiga, V.; Nayak, S.; Sahoo, P.N.; Sharma, P.K.; Meijgaarden, K.E. van; Jesuraj, U.J.A.; Dhar, C.; Souza, G.D.; Finak, G.; Rosa, S.C. de; Ottenhoff, T.H.M. & Vyakarnam, A. (2017), Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10(+) Th17 CD4 T-cells differentiate latent from active tuberculosis, Scientific Reports 7.
- Coppola, M.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Commandeur, S.; Dolganov, G.; Kramnik, I.; Schoolnik, G.K.; Comas, I.; Lund, O.; Prins, C.; Eeden, S.J.F. van den; Korsvold, G.E.; Oftung, F.; Geluk, A. & Ottenhoff, T.H.M. (2016), New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles, Scientific Reports 6.
- Joosten, S.A.; Meijgaarden, K.E. van; Nonno, F. del; Baiocchini, A.; Petrone, L.; Vanini, V.; Smits, H.H.; Palmieri, F.; Goletti, D. & Ottenhoff, T.H.M. (2016), Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment, PLoS Pathogens 12(6).
- Rakshit, S.; Sundararaj, B.K.; Sahoo, P.N.; Ottenhoff, T.H.M.; Meijgaarden, K.E. van; Jesuraj, A.; D'Souza, G. & Vyakarnam, A. (2016), Comparative analysis of the host mediated antigen-specific responses In Indian cohorts with different TB infected states, International Journal of Infectious Diseases 45: 407-407.
- Boer, M.C.; Meijgaarden, K.E. van; Goletti, D.; Vanini, V.; Prins, C.; Ottenhoff, T.H.M. & Joosten, S.A. (2016), KLRG1 and PD-1 expression are increased on T-cells following tuberculosis-treatment and identify cells with different proliferative capacities in BCG-vaccinated adults, Tuberculosis 97: 163-171.
- Khadge, S.; Banu, S.; Bobosha, K.; Ploeg-van Schip, J.J. van der; Goulart, I.M.; Thapa, P.; Kunwar, C.B.; Meijgaarden, K.E. van; Eeden, S.J.F. van den; Wilson, L.; Kabir, S.; Dey, H.; Goulart, L.R.; Lobato, J.; Carvalho, W.; Bekele, Y.; Franken, K.L.M.C.; Aseffa, A.; Spencer, J.S.; Oskam, L.; Otttenhoff, T.H.M.; Hagge, D.A. & Geluk, A. (2015), Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal, BMC Infectious Diseases 15.
- Smith, S.G.; Smits, K.; Joosten, S.A.; Meijgaarden, K.E. van; Satti, I.; Fletcher, H.A.; Caccamo, N.; Dieli, F.; Mascart, F.; McShane, H.; Dockrell, H.M.; Ottenhoff, T.H.M. & TBVI TB Biomarker Working Grp (2015), Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines, PLoS ONE 10(9).
- Boer, M.C.; Prins, C.; Meijgaarden, K.E. van; Dissel, J.T. van; Ottenhoff, T.H.M. & Joosten, S.A. (2015), Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults, Clinical and Vaccine Immunology 22(7): 778-788.
- Caccamo, N.; Pietra, G.; Sullivan, L.C.; Brooks, A.G.; Prezzemolo, T.; Manna, M.P. la; Liberto, D. di; Joosten, S.A.; Meijgaarden, K.E. van; Carlo, P. di; Titone, L.; Moretta, L.; Mingari, M.C.; Ottenhoff, T.H.M. & Dieli, F. (2015), Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines, European Journal of Immunology 45(4): 1069-1081.
- Meijgaarden, K.E. van; Haks, M.C.; Caccamo, N.; Dieli, F.; Ottenhoff, T.H.M. & Joosten, S.A. (2015), Human CD8(+) T-cells Recognizing Peptides from Mycobacterium tuberculosis (Mtb) Presented by HLA-E Have an Unorthodox Th2-like, Multifunctional, Mtb Inhibitory Phenotype and Represent a Novel Human T-cell Subset, PLoS Pathogens 11(3).
- (2015), BCG-vaccination induces divergent pro-inflammatory or regulatory T-cell responses in adults., Clinical and Vaccine Immunology.
- Caccamo, N.; Pietra, G.; Sullivan, L.C.; Brooks, A.G.; Prezzemolo, T.; Joosten, S.; Manna, M.P. la; Liberto, D. di; Meijgaarden, K.E. van; Carlo, P. di; Titone, L.; Moretta, L.; Mingari, M.C.; Ottenhoff, T.H.M. & Dieli, F. (2014), Analysis of CD8 T-cells recognising Mycobacterium tuberculosis antigen presented by HLA-E molecule, Immunology 143: 69-69.
- Geluk Annemieke, van Meijgaarden Krista E., Joosten Simone A., Commandeur Susanna & Ottenhoff Tom H. M. (2014), Innovative strategies to identify M. tuberculosis antigens and epitopes using genome-wide analyses, Frontiers in Immunology 5.
- Commandeur, S.; Eeden, S.J.F. van den; Dijkman, K.; Clark, S.O.; Meijgaarden, K.E. van; Wilson, L.; Franken, K.L.M.C.; Williams, A.; Christensen, D.; Ottenhoff, T.H.M. & Geluk, A. (2014), The in vivo expressed Mycobacterium tuberculosis (IVE-TB) antigen Rv2034 induces CD4(+) T-cells that protect against pulmonary infection in HLA-DR transgenic mice and guinea pigs, Vaccine 32(29): 3580-3588.
- Commandeur, S.; Coppola, M.; Dijkman, K.; Friggen, A.H.; Meijgaarden, K.E. van; Eeden, S.J.F. van den; Wilson, L.; Ploeg-van Schip, J.J. van der; Franken, K.L.M.C.; Geluk, A. & Ottenhoff, T.H.M. (2014), Clonal Analysis of the T-Cell Response to In Vivo Expressed Mycobacterium tuberculosis Protein Rv2034, Using a CD154 Expression Based T-Cell Cloning Method, PLoS ONE 9(6).
- Bobosha, K.; Wilson, L.; Meijgaarden, K.E. van; Bekele, Y.; Zewdie, M.; Ploeg-van Schip, J.J. van der; Abebe, M.; Hussein, J.; Khadge, S.; Neupane, K.D.; Hagge, D.A.; Jordanova, E.S.; Aseffa, A.; Ottenhoff, T.H.M. & Geluk, A. (2014), T-Cell Regulation in Lepromatous Leprosy, PLoS Neglected Tropical Diseases 8(4).
- Boer, M.C.; Meijgaarden, K.E. van; Joosten, S.A. & Ottenhoff, T.H.M. (2014), CD8(+) Regulatory T Cells, and Not CD4(+) T Cells, Dominate Suppressive Phenotype and Function after In Vitro Live Mycobacterium bovis-BCG Activation of Human Cells, PLoS ONE 9(4).
- Geluk, A.; Meijgaarden, K.E. van; Wilson, L.; Bobosha, K.; Schip, J.J.V.D.P.V.; Eeden, S.J.F. van den; Quinten, E.; Dijkman, K.; Franken, K.L.M.C.; Haisma, E.M.; Haks, M.C.; Hees, C.L.M. van & Ottenhoff, T.H.M. (2014), Longitudinal Immune Responses and Gene Expression Profiles in Type 1 Leprosy Reactions, Journal of Clinical Immunology 34(2): 245-255.
- Boer, M.C.; Meijgaarden, K.E. van; Bastid, J.; Ottenhoff, T.H.M. & Joosten, S.A. (2013), CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8+CD39+regulatory T cells, European Journal of Immunology 43(7): 1925-1932.
- Boer, M.C.; Meijgaarden, K.E. van; Bastid, J.; Ottenhoff, T.H.M. & Joosten, S.A. (2013), CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8(+) CD39(+) regulatory T cells., European Journal of Immunology 43(7): 1925-32.
- Commandeur, S.; Meijgaarden, K.E. van; Prins, C.; Pichugin, A.V.; Dijkman, K.; Eeden, S.J.F. van den; Friggen, A.H.; Franken, K.L.M.C.; Dolganov, G.; Kramnik, I.; Schoolnik, G.K.; Oftung, F.; Korsvold, G.E.; Geluk, A. & Ottenhoff, T.H.M. (2013), An Unbiased Genome-Wide Mycobacterium tuberculosis Gene Expression Approach To Discover Antigens Targeted by Human T Cells Expressed during Pulmonary Infection, Journal of Immunology 190(4): 1659-1671.
- Kassa, D.; Ran, L.; Geberemeskel, W.; Tebeje, M.; Alemu, A.; Selase, A.; Tegbaru, B.; Franken, K.L.M.C.; Friggen, A.H.; Meijgaarden, K.E. van; Ottenhoff, T.H.M.; Wolday, D.; Messele, T. & Baarle, D. van (2012), Analysis of Immune Responses against a Wide Range of Mycobacterium tuberculosis Antigens in Patients with Active Pulmonary Tuberculosis.
- Does, A.M. van der; Joosten, S.A.; Vroomans, E.; Bogaards, S.J.P.; Meijgaarden, K.E. van; Ottenhoff, T.H.M.; Dissel, J.T. van & Nibbering, P.H. (2012), The Antimicrobial Peptide hLF1-11 Drives Monocyte-Dendritic Cell Differentiation toward Dendritic Cells That Promote Antifungal Responses and Enhance Th17 Polarization, Journal of Innate Immunity 4(3): 284-292.
- Geluk, A.; Eeden, S.J.F. van den; Meijgaarden, K.E. van; Dijkman, K.; Franken, K.L.M.C. & Ottenhoff, T.H.M. (2012), A multistage-polyepitope vaccine protects against Mycobacterium tuberculosis infection in HLA-DR3 transgenic mice, Vaccine 30(52): 7513-7521.
- Riano, F.; Arroyo, L.; Paris, S.; Rojas, M.; Friggen, A.H.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Garcia, L.F. & Barrera, L.F. (2012), T cell responses to DosR and Rpf proteins in actively and latently infected individuals from Colombia.
- Commandeur, S.; Lin, M.Y.; Meijgaarden, K.E. van; Friggen, A.H.; Franken, K.L.M.C.; Drijfhout, J.W.; Korsvold, G.E.; Oftung, F.; Geluk, A. & Ottenhoff, T.H.M. (2011), Double- and monofunctional CD4(+) and CD8(+) T-cell responses to Mycobacterium tuberculosis DosR antigens and peptides in long-term latently infected individuals, European Journal of Immunology 41(10): 2925-2936.
- Corstjens, P.L.A.M.; Dood, C.J. de; Ploeg-van Schip, J.J. van der; Wiesmeijer, K.C.; Riuttamaki, T.; Meijgaarden, K.E. van; Spencer, J.S.; Tanke, H.J.; Ottenhoff, T.H.M. & Geluk, A. (2011), Lateral flow assay for simultaneous detection of cellular- and humoral immune responses, Clinical Biochemistry 44(14-15): 1241-1246.
- Corstjens, P.L.A.M.; Dood, C.J. de; Ploeg-van Schip, J.J. van der; Wiesmeijer, K.C.; Riuttamaki, T.; Meijgaarden, K.E. van; Spencer, J.S.; Tanke, H.J.; Ottenhoff, T.H.M. & Geluk, A. (2011), Lateral flow assay for simultaneous detection of cellular- and humoral immune responses., Clinical Biochemistry.
- Commandeur, S.; Meijgaarden, K.E. van; Lin, M.Y.; Franken, K.L.M.C.; Friggen, A.H.; Drijfhout, J.W.; Oftung, F.; Korsvold, G.E.; Geluk, A. & Ottenhoff, T.H.M. (2011), Identification of Human T-Cell Responses to Mycobacterium tuberculosis Resuscitation-Promoting Factors in Long-Term Latently Infected Individuals, Clinical and Vaccine Immunology 18(4): 676-683.
- Tang, S.T.; Meijgaarden, K.E. van; Caccamo, N.; Guggino, G.; Klein, M.R.; Weeren, P. van; Kazi, F.; Stryhn, A.; Zaigler, A.; Sahin, U.; Buus, S.; Dieli, F.; Lund, O. & Ottenhoff, T.H.M. (2011), Genome-Based In Silico Identification of New Mycobacterium tuberculosis Antigens Activating Polyfunctional CD8(+) T Cells in Human Tuberculosis, Journal of Immunology 186(2): 1068-1080.
- Geluk, A.; Ploeg-van Schip, J.J. van der; Meijgaarden, K.E. van; Commandeur, S.; Drijfhout, J.W.; Benckhuijsen, W.E.; Franken, K.L.M.C.; Naafs, B. & Ottenhoff, T.H.M. (2010), Enhancing sensitivity of detection of immune responses to Mycobacterium leprae peptides in whole-blood assays.
- Joosten, S.A.; Meijgaarden, K.E. van; Weeren, P.C. van; Kazi, F.; Geluk, A.; Savage, N.D.L.; Drijfhout, J.W.; Flower, D.R.; Hanekom, W.A.; Klein, M.R. & Ottenhoff, T.H.M. (2010), Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity., PLoS Pathogens 6(2): e1000782.
- Lin MY, Reddy TBK, Arend SM, Friggen AH, Franken KLMC, van Meijgaarden KE, Verduyn MJC, Schoolnik GK, Klein MR & Ottenhoff THM (2009), Cross-Reactive Immunity to Mycobacterium tuberculosis DosR Regulon-Encoded Antigens in Individuals Infected with Environmental, Nontuberculous Mycobacteria, Infection and Immunity 77(11): 5071-5079.
- Bivas-Benita M, Lin MY, Bal SM, van Meijgaarden KE, Franken KLMC, Friggen AH, Junginger HE, Borchard G, Klein MR & Ottenhoff THM (2009), Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice, Vaccine 27(30): 4010-4017.
- Joosten SA, van Meijgaarden KE, Savage NDL, de Boert T, Triebel F, van der Wal A, de Heer E, Klein MR, Geluk A & Ottenhoff THM (2007), Identification of a human CD8(+) regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4, Proceedings of the National Academy of Sciences 104(19).
- Kriek NMAJ, van der Hout E, Kelly P, van Meijgaarden KE, Geluk A, Ottenhoff THM, van der Marel GA, Overhand M, van Boom JH, Valentijn ARPM & Overkleeft HS (2003), Synthesis of novel tetrahydropyran-based dipeptide isosters by Overman rearrangement of 2,3-didehydroglycosides, European Journal of Organic Chemistry.
- Arend SM, van Meijgaarden KE, de Boer K, de Palou EC, van Soolingen D, Ottenhoff THM & van Dissel JT (2002), Tuberculin skin testing and in vitro T cell responses to ESAT-6 and culture filtrate protein 10 after infection with Mycobacterium marinum or M-kansasii, Journal of Infectious Diseases 186(12).
- de Jong A, van der Burg SH, Kwappenberg KMC, van der Hulst JM, Franken KLMC, Geluk A, van Meijgaarden KE, Drijfhout JW, Kenter G, Vermeij P, Melief CJM & Offringa R (2002), Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects, Cancer Research 62(2).
- van der Burg SH, Ressing ME, Kwappenberg KMC, de Jong A, Straathof K, de Jong J, Geluk A, van Meijgaarden KE, Franken KLMC, Ottenhoff THM, Fleuren GJ, Kenter G, Melief CJM & Offringa R (2001), Natural T-HELPER immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: Identification of 3 human leukocyte antigen class II-restricted epitopes, International Journal of Cancer 91(5).
- Vos K, Miltenburg AMM, van Meijgaarden KE, van den Heuvel M, Elferink DG, van Galen PJM, van Hogezand RA, van Vliet-Daskalopoulou E, Ottenhoff THM, Breedveld FC, Boots AMH & de Vries RRP (2000), Cellular immune response to human cartilage glycoprotein-39 (HC gp-39)-derived peptides in rheumatoid arthritis and other inflammatory conditions, Rheumatology 39(12).
- Franken KLMC, Hiemstra HS, van Meijgaarden KE, Subronto Y, den Hartigh J, Ottenhoff THM & Drijfhout JW (2000), Purification of His-tagged proteins by immobilized chelate affinity chromatography: The benefits from the use of organic solvent.
- Hiemstra HS, van Veelen PA, Schloot NC, Geluk A, van Meijgaarden KE, Willemen SJM, Leunissen JAM, Benckhuijsen WE, Amons R, de Vries RRP, Roep BO, Ottenhoff THM & Drijfhout JW (1998), Definition of natural T cell antigens with mimicry epitopes obtained from dedicated synthetic peptide libraries, Journal of Immunology 161(8): 4078-4082.