Professor Molecular Stem Cell Biology
The research of Frank J.T. Staal focuses on molecular regulation of immature T lymphocyte development and hematopoietic stem cell biology. Besides basic aspects of transcriptional regulation and cell signalling in mouse and human, this knowledge is applied to diagnosis and gene therapy applications of primary human immunodeficiencies as well as to abnormal lymphoid development in acute lymphoblastic leukemias. Translational research leading to novel diagnostic and therapeutic tools is an integral part of his research activities.
The title of his inaugural lecture was 'To T or not to T' (1 november 2008).