D.M.F.M. van der Heijde
Professor Rheumatology, in particular outcome research
The focus of my research is on outcome assessment: what is the best way to assess outcome and what is the final outcome with and without treatment, what are predictors of outcome. Most of the research is focused around spondyloarthritis including ankylosing spondylitis and rheumatoid arthritis. There is a special interest in imaging outcome: plain radiography as well as MRI. Validation and standardisation of outcome tools has led to the international acceptance of (among others) the following by own research developed and validated instruments: the DAS (disease activity score) in rheumatoid arthritis; the Sharp-van der Heijde method for scoring radiographs of hands and feet in rheumatoid arthritis; the modified SASS method for spine radiographs in ankylosing spondylitis; the ASspiMRI score for assessment of MRI of the spine in ankylosing spondylitis; core sets for ankylosing spondylitis for inclusion in research. Furthermore this has been implemented in a plethora of clinical trials, especially on the use of TNF-blockers in patients with rheumatoid arthritis and ankylosing spondylitis resulting in over original 280 papers in the international literature.
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