Universiteit Leiden

nl en

D.M.F.M. van der Heijde

Professor Rheumatology, in particular outcome research

Prof.dr. D.M.F.M. van der Heijde
+31 71 526 3647


The focus of my research is on outcome assessment: what is the best way to assess outcome and what is the final outcome with and without treatment, what are predictors of outcome. Most of the research is focused around spondyloarthritis including ankylosing spondylitis and rheumatoid arthritis. There is a special interest in imaging outcome: plain radiography as well as MRI. Validation and standardisation of outcome tools has led to the international acceptance of (among others) the following by own research developed and validated instruments: the DAS (disease activity score) in rheumatoid arthritis; the Sharp-van der Heijde method for scoring radiographs of hands and feet in rheumatoid arthritis; the modified SASS method for spine radiographs in ankylosing spondylitis; the ASspiMRI score for assessment of MRI of the spine in ankylosing spondylitis; core sets for ankylosing spondylitis for inclusion in research. Furthermore this has been implemented in a plethora of clinical trials, especially on the use of TNF-blockers in patients with rheumatoid arthritis and ankylosing spondylitis resulting in over original 280 papers in the international literature.

Professor Rheumatology, in particular outcome research

  • Faculteit Geneeskunde
  • Divisie 2
  • Reumatologie

Work address

LUMC Main Building
Albinusdreef 2
2333 ZA Leiden
Room number C1-R


  • Annals of Rheumatic Diseases Lid advisory board
  • Bechterew patientenvereniging adviseur
  • EULAR bij ACR (American Society) vertegenwoordiger
  • EULAR executive committee lid
  • EULAR standing committee ESCCA Voorzitter
  • EULAR task force longterm trials lid
  • EULAR task force management axSpa voorzitter
  • EULAR task force management RA lid
  • EULAR task force on imaging in SpA lid
  • GESPIC adviseur
  • Imaging Rheumatology BV Directeur
  • International advisory board ARRIMAGE, research network of French universities lid
  • RMD Open Lid editorial board
  • SpA en PsA Voorzitter abstract selection ACR
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