Cornelis Franken
- Name
- C.L.M.C. Franken
- Telephone
- +31 71 526 3800
- c.l.m.c.franken@umail.leidenuniv.nl
- Faculteit Geneeskunde
- Divisie 4
- Immunohematologie en Bloedtransfusie
- IHB HLA en ziekten
- Hooij, A. van; Eeden, S.J.F. van den; Khatun, M.; Soren, S.; Franken, K.L.M.C.; Roy, J.C.; Alam, K.; Chowdhury, A.; Richardus, J.H. & Geluk, A. (2021), BCG-induced immunity profiles in household contacts of leprosy patients differentiate between protection and disease, Vaccine 39(50): 7230-7237.
- Coppola, M.; Jurion, F.; Eeden, S.J.F. van den; Tima, H.G.; Franken, K.L.M.C.; Geluk, A.; Romano, M. & Ottenhoff, T.H.M. (2021), In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination, npj Vaccines 6(1).
- Adankwah, E.; Nausch, N.; Minadzi, D.; Abass, M.K.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Mayatepek, E.; Phillips, R.O. & Jacobsen, M. (2021), Interleukin-6 and Mycobacterium tuberculosis dormancy antigens improve diagnosis of tuberculosis, Journal of Infection 82(2): 245-252.
- Nejad, E.B.; Labrie, C.; Elsas, M.J. van; Kleinovink, J.W.; Mittrucker, H.W.; Franken, K.L.M.C.; Heink, S.; Korn, T.; Arens, R.; Hall, T. van & Burg, S.H. van der (2021), IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors, Journal for ImmunoTherapy of Cancer 9(4).
- Ruibal, P.; Franken, K.L.M.C.; Meijgaarden, K.E. van; Loon, J.J.F. van; Steen, D. van der; Heemskerk, M.H.M.; Ottenhoff, T.H.M. & Joosten, S.A. (2020), Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues, Journal of Immunology 205(10): 2861-2872.
- Ortega, P.A.; Silva-Miranda, M.; Torres-Larios, A.; Campos-Chavez, E.; Franken, K.C.L.C.M.; Ottenhoff, T.H.M.; Ivanyi, J. & Espitia, C. (2020), Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen, Frontiers in Immunology 11.
- Nejad, E.B.; Labrie, C.; Sluis, T.C. van der; Duikeren, S. van; Franken, K.L.M.C.; Roosenhoff, R.; Arens, R.; Hall, T. van & Burg, S.H. van der (2020), Interleukin-6-mediated resistance to immunotherapy is linked to impaired myeloid cell function, International Journal of Cancer.
- Loon, W. van; Gomez, M.P.; Jobe, D.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Coninx, M.; Kestens, L.; Sutherland, J.S.; Kampmann, B. & Tientcheu, L.D. (2020), Use of resuscitation promoting factors to screen for tuberculosis infection in household-exposed children in The Gambia, BMC Infectious Diseases 20(1).
- Coppola, M.; Villar-Hernandez, R.; Meijgaarden, K.E. van; Latorre, I.; Moreno, B.M.; Garcia-Garcia, E.; Franken, K.L.M.C.; Prat, C.; Stojanovic, Z.; Galvao, M.L.D.; Millet, J.P.; Sabria, J.; Sanchez-Montalva, A.; Noguera-Julian, A.; Geluk, A.; Dominguez, J. & Ottenhoff, T.H.M. (2020), Cell-Mediated Immune Responses to in vivo-Expressed and Stage-Specific Mycobacterium tuberculosis Antigens in Latent and Active Tuberculosis Across Different Age Groups, Frontiers in Immunology 11.
- Kemps, P.G.; Zondag, T.C.; Steenwijk, E.C.; Andriessen, Q.; Borst, J.; Vloemans, S.; Roelen, D.L.; Voortman, L.M.; Verdijk, R.M.; Noesel, C.J.M. van; Cleven, A.H.G.; Hawkins, C.; Lang, V.; Ru, A.H. de; Janssen, G.M.C.; Haasnoot, G.W.; Franken, K.L.M.C.; Eijk, R. van; Solleveld-Westerink, N.; Wezel, T. van; Egeler, R.M.; Beishuizen, A.; Laar, J.A.M. van; Abla, O.; Bos, C. van den; Veelen, P.A. van & Halteren, A.G.S. van (2020), Apparent Lack of BRAF(V600E) Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8(+) T Cells in Langerhans Cell Histiocytosis, Frontiers in Immunology 10.
- Hos, B.J.; Camps, M.G.M.; Bulk, J. van den; Tondini, E.; Ende, T.C. van den; Ruano, D.; Franken, K.; Janssen, G.M.C.; Ru, A.; Filippov, D.V.; Arens, R.; Veelen, P.A. van; Miranda, N. & Ossendorp, F. (2020), Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer, ONCOIMMUNOLOGY 9(1).
- Rakshit, S.; Ahmed, A.; Adiga, V.; Sundararaj, B.K.; Sahoo, P.N.; Kenneth, J.; D'Souza, G.; Bonam, W.; Johnson, C.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Finak, G.; Gottardo, R.; Stuart, K.D.; Rosa, S.C. de; McElrath, M.J. & Vyakarnam, A. (2019), BCG revaccination boosts adaptive polyfunctional Th1/Th17 and innate effectors in IGRA(+) and IGRA(-) Indian adults, JCI insight 4(24).
- Hooij, A. van; Eeden, S. van den; Richardus, R.; Fat, E.T.K.; Wilson, L.; Franken, K.L.M.C.; Faber, R.; Khatun, M.; Alam, K.; Chowdhury, A.S.; Richardus, J.H.; Corstjens, P. & Geluk, A. (2019), Application of new host biomarker profiles in quantitative point-of-care tests facilitates leprosy diagnosis in the field, EBioMedicine 47: 301-308.
- Adankwah, E.; Lundtoft, C.; Guler, A.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Mayatepek, E.; Owusu-Dabo, E.; Phillips, R.O.; Nausch, N. & Jacobsen, M. (2019), Two-Hit in vitro T-Cell Stimulation Detects Mycobacterium tuberculosis Infection in QuantiFERON Negative Tuberculosis Patients and Healthy Contacts From Ghana, Frontiers in Immunology 10.
- Veldhuijzen, N.; Lenz, S.M.; Collins, J.H.; Ray, N.A.; Deming, A.T.; Lahiri, R.; Adams, L.B.; Hooij, A. van; Eeden, S. van den; Richardus, R.; Wilson, L.; Franken, K.L.M.; Faber, R.; Khatun, M.; Alam, K.; Richardus, J.H.; Geluk, A.; Balagon, M.; Roferos, F.; Abellana, J.; Taborada, T.; Sanchez, R.; Maghanoy, A.; Engelbrektsson, U.B.; Magar, D.B.; Sserunkuma, M.C.; Moses, K.; Ssembatya, B.B.; LRI Scien Review Comm & LRI Steering Comm (2019), Meeting report: the Leprosy Research Initiative Spring Meeting, Leprosy Review 90(2): 183-200.
- Prezzemolo, T.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Caccamo, N.; Dieli, F.; Ottenhoff, T.H.M. & Joosten, S.A. (2018), Detailed characterization of human Mycobacterium tuberculosis specific HLA-E restricted CD8(+) T cells, European Journal of Immunology 48(2): 293-305.
- Coppola, M.; Eeden, S.J.F. van den; Robbins, N.; Wilson, L.; Franken, K.L.M.C.; Adams, L.B.; Gillis, T.P.; Ottenhoff, T.H.M. & Geluk, A. (2018), Vaccines for Leprosy and Tuberculosis: Opportunities for Shared Research, Development, and Application, Frontiers in Immunology 9.
- Abebe, F.; Belay, M.; Legesse, M.; Franken, K.L.M.C. & Ottenhoff, T.H.M. (2018), IgA and IgG against Mycobacterium tuberculosis Rv2031 discriminate between pulmonary tuberculosis patients, Mycobacterium tuberculosis-infected and non-infected individuals, PLoS ONE 13(1).
- Korbee, C.J.; Heemskerk, M.T.; Kocev, D.; Strijen, E. van; Rabiee, O.; Franken, K.L.M.C.; Wilson, L.; Savage, N.D.L.; Dzeroski, S.; Haks, M.C. & Ottenhoff, T.H.M. (2018), Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials, Nature Communications 9.
- Arroyo, L.; Marin, D.; Franken, K.L.M.C.; Ottenhoff, T.H.M. & Barrera, L.F. (2018), Potential of DosR and Rpf antigens from Mycobacterium tuberculosis to discriminate between latent and active tuberculosis in a tuberculosis endemic population of Medellin Colombia, BMC Infectious Diseases 18.
- Kimuda, S.G.; Nalwoga, A.; Levin, J.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Elliott, A.M.; Cose, S. & Andia-Biraro, I. (2017), Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection, Journal of Immunology Research.
- Coppola, M.; Arroyo, L.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Geluk, A.; Barrera, L.F. & Ottenhoff, T.H.M. (2017), Differences in IgG responses against infection phase related Mycobacterium tuberculosis (Mtb) specific antigens in individuals exposed or not to Mtb correlate with control of TB infection and progression, Tuberculosis 106: 25-32.
- Breman, E.; Ruben, J.M.; Franken, K.L.; Heemskerk, M.H.M.; Roelen, D.L.; Claas, F.H. & Kooten, C. van (2016), Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition, Journal of Immunology Research.
- Coppola, M.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Commandeur, S.; Dolganov, G.; Kramnik, I.; Schoolnik, G.K.; Comas, I.; Lund, O.; Prins, C.; Eeden, S.J.F. van den; Korsvold, G.E.; Oftung, F.; Geluk, A. & Ottenhoff, T.H.M. (2016), New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles, Scientific Reports 6.
- Arroyo, L.; Rojas, M.; Franken, K.L.M.C.; Ottenhoff, T.H.M. & Barrera, L.F. (2016), Multifunctional T Cell Response to DosR and Rpf Antigens Is Associated with Protection in Long-Term Mycobacterium tuberculosis-Infected Individuals in Colombia, Clinical and Vaccine Immunology 23(10): 813-824.
- Panagioti, E.; Redeker, A.; Duikeren, S. van; Franken, K.L.M.C.; Drijfhout, J.W.; Burg, S.H. van der & Arens, R. (2016), The Breadth of Synthetic Long Peptide Vaccine-Induced CD8(+) T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection, PLoS Pathogens 12(9).
- Teixeira, H.C.; Mattos, A.M.M.; Almeida, C.S.; Abad, L.P.M.; Franken, K. & Ottenhoff, T.H.M. (2016), IgG1 and Th1 responses to DosR, Rpf and active growth phase antigens of Mycobacterium tuberculosis in Brazilian tuberculosis patients, Journal of Immunology 196.
- Arroyo, L.; Rojas, M.; Ortiz, B.L.; Franken, K.L.M.C.; Garcia, L.F.; Ottenhoff, T.H.M. & Barrera, L.F. (2016), Dynamics of the T cell response to Mycobacterium tuberculosis DosR and Rpf antigens in a Colombian population of household contacts of recently diagnosed pulmonary tuberculosis patients, Tuberculosis 97: 97-107.
- Belay, M.; Legesse, M.; Mihret, A.; Ottenhoff, T.H.M.; Franken, K.L.; Bjune, G. & Abebe, F. (2016), IFN-gamma and IgA against non-methylated heparin-binding hemagglutinin as markers of protective immunity and latent tuberculosis: Results of a longitudinal study from an endemic setting.
- Mattos, A.M.M.; Chaves, A.S.; Franken, K.L.M.C.; Figueiredo, B.B.M.; Ferreira, A.P.; Ottenhoff, T.H.M. & Teixeira, H.C. (2016), Detection of IgG1 antibodies against Mycobacterium tuberculosis DosR and Rpf antigens in tuberculosis patients before and after chemotherapy.
- Corstjens, P.L.A.M.; Fat, E.M.T.K.; Dood, C.J. de; Ploeg-van Schip, J.J.V. van der; Franken, K.L.M.C.; Chegou, N.N.; Sutherland, J.S.; Howe, R.; Mihret, A.; Kassa, D.; Vyver, M. van der; Sheehama, J.; Simukonda, F.; Mayanja-Kizza, H.; Ottenhoff, T.H.M.; Walzl, G.; Geluk, A. & AE-TBC Consortium (2016), Multi-center evaluation of a user-friendly lateral flow assay to determine IP-10 and CCL4 levels in blood of TB and non-TB cases in Africa, Clinical Biochemistry 49(1-2): 22-31.
- Khadge, S.; Banu, S.; Bobosha, K.; Ploeg-van Schip, J.J. van der; Goulart, I.M.; Thapa, P.; Kunwar, C.B.; Meijgaarden, K.E. van; Eeden, S.J.F. van den; Wilson, L.; Kabir, S.; Dey, H.; Goulart, L.R.; Lobato, J.; Carvalho, W.; Bekele, Y.; Franken, K.L.M.C.; Aseffa, A.; Spencer, J.S.; Oskam, L.; Otttenhoff, T.H.M.; Hagge, D.A. & Geluk, A. (2015), Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal, BMC Infectious Diseases 15.
- Yazdi, M.T.; Loof, N.M.; Franken, K.L.M.C.; Taube, C.; Oostendorp, J.; Hiemstra, P.S.; Welters, M.J.P. & Burg, S.H. van der (2015), Local and systemic XAGE-1b-specific immunity in patients with lung adenocarcinoma, Cancer Immunology, Immunotherapy 64(9): 1109-1121.
- Coppola, M.; Eeden, S.J.F. van den; Wilson, L.; Franken, K.L.M.C.; Ottenhoff, T.H.M. & Geluk, A. (2015), Synthetic Long Peptide Derived from Mycobacterium tuberculosis Latency Antigen Rv1733c Protects against Tuberculosis, Clinical and Vaccine Immunology 22(9): 1060-1069.
- Belay, M.; Legesse, M.; Mihret, A.; Bekele, Y.; Ottenhoff, T.H.M.; Franken, K.L.M.C.; Bjune, G. & Abebe, F. (2015), Pro- and Anti-Inflammatory Cytokines against Rv2031 Are Elevated during Latent Tuberculosis: A Study in Cohorts of Tuberculosis Patients, Household Contacts and Community Controls in an Endemic Setting, PLoS ONE 10(4).
- Mar Serra-Vidal, M.A. del; Latorre, I.; Franken, K.L.C.M.; Diaz, J.; Souza-Galvao, M.L. de; Casas, I.; Maldonado, J.; Mila, C.; Solsona, J.; Jimenez-Fuentes, M.A.; Altet, N.; Lacoma, A.; Ruiz-Manzano, J.; Ausina, V.; Prat, C.; Ottenhoff, T.H.M. & Dominguez, J. (2014), Immunogenicity of 60 novel latency-related antigens of Mycobacterium tuberculosis, Frontiers in Microbiology 5.
- Essone, P.N.; Chegou, N.N.; Loxton, A.G.; Stanley, K.; Kriel, M.; Spuy, G. van der; Franken, K.L.; Ottenhoff, T.H. & Walzl, G. (2014), Host Cytokine Responses Induced after Overnight Stimulation with Novel M-tuberculosis Infection Phase-Dependent Antigens Show Promise as Diagnostic Candidates for TB Disease, PLoS ONE 9(7).
- Commandeur, S.; Eeden, S.J.F. van den; Dijkman, K.; Clark, S.O.; Meijgaarden, K.E. van; Wilson, L.; Franken, K.L.M.C.; Williams, A.; Christensen, D.; Ottenhoff, T.H.M. & Geluk, A. (2014), The in vivo expressed Mycobacterium tuberculosis (IVE-TB) antigen Rv2034 induces CD4(+) T-cells that protect against pulmonary infection in HLA-DR transgenic mice and guinea pigs, Vaccine 32(29): 3580-3588.
- Commandeur, S.; Coppola, M.; Dijkman, K.; Friggen, A.H.; Meijgaarden, K.E. van; Eeden, S.J.F. van den; Wilson, L.; Ploeg-van Schip, J.J. van der; Franken, K.L.M.C.; Geluk, A. & Ottenhoff, T.H.M. (2014), Clonal Analysis of the T-Cell Response to In Vivo Expressed Mycobacterium tuberculosis Protein Rv2034, Using a CD154 Expression Based T-Cell Cloning Method, PLoS ONE 9(6).
- Bobosha, K.; Fat, E.M.T.K.; Eeden, S.J.F. van den; Bekele, Y.; Ploeg-van Schip, J.J. van der; Dood, C.J. de; Dijkman, K.; Franken, K.L.M.C.; Wilson, L.; Aseffa, A.; Spencer, J.S.; Ottenhoff, T.H.M.; Corstjens, P.L.A.M. & Geluk, A. (2014), Field-Evaluation of a New Lateral Flow Assay for Detection of Cellular and Humoral Immunity against Mycobacterium leprae, PLoS Neglected Tropical Diseases 8(5).
- Assohou-Luty, C.; Raijmakers, R.; Benckhuijsen, W.E.; Stammen-Vogelzangs, J.; Ru, A. de; Veelen, P.A. van; Franken, K.L.M.C.; Drijfhout, J.W. & Pruijn, G.J.M. (2014), The human peptidylarginine deiminases type 2 and type 4 have distinct substrate specificities, BBA - Proteins and Proteomics 1844(4): 829-836.
- Huang, W.; Qi, Y.J.; Diao, Y.J.; Yang, F.; Zha, X.D.; Ren, C.P.; Huang, D.K.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Wu, Q.S. & Shen, J.J. (2014), Use of Resuscitation-Promoting Factor Proteins Improves the Sensitivity of Culture-based Tuberculosis Testing in Special Samples, American Journal of Respiratory and Critical Care Medicine 189(5): 612-614.
- Geluk, A.; Meijgaarden, K.E. van; Wilson, L.; Bobosha, K.; Schip, J.J.V.D.P.V.; Eeden, S.J.F. van den; Quinten, E.; Dijkman, K.; Franken, K.L.M.C.; Haisma, E.M.; Haks, M.C.; Hees, C.L.M. van & Ottenhoff, T.H.M. (2014), Longitudinal Immune Responses and Gene Expression Profiles in Type 1 Leprosy Reactions, Journal of Clinical Immunology 34(2): 245-255.
- Huis-Tanja, L.H. van; Kweekel, D.M.; Lu, X.B.; Franken, K.; Koopman, M.; Gelderblom, H.; Antonini, N.F.; Punt, C.J.A.; Guchelaar, H.J. & Straaten, T. van der (2014), Excision Repair Cross-Complementation group 1 (ERCC1) C118T SNP does not affect cellular response to oxaliplatin, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 759: 37-44.
- Huang, W.; Qi, Y.J.; Ren, C.P.; Wen, H.; Franken, K.L.M.C.; Ottenhoff, T.H.M. & Shen, J.J. (2013), Interferon-gamma responses to Mycobacterium tuberculosis Rpf proteins in contact investigation, Tuberculosis 93(6): 612-617.
- Huang, W.; Qi, Y.J.; Ren, C.P.; Wen, H.; Franken, K.L.M.C.; Ottenhoff, T.H.M. & Shen, J.J. (2013), Interferon-γ responses to Mycobacterium tuberculosis Rpf proteins in contact investigation., Tuberculosis 93(6): 612-7.
- Rosalia, R.A.; Quakkelaar, E.D.; Redeker, A.; Khan, S.; Camps, M.; Drijfhout, J.W.; Silva, A.L.; Jiskoot, W.; Hall, T. van; Veelen, P.A. van; Janssen, G.; Franken, K.; Cruz, L.J.; Tromp, A.; Oostendorp, J.; derBurg, S.H. van; Ossendorp, F. & Melief, C.J.M. (2013), Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation, European Journal of Immunology 43(10): 2554-2565.
- Legesse, M.; Ameni, G.; Medhin, G.; Mamo, G.; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Bjune, G. & Abebe, F. (2013), IgA Response to ESAT-6/CFP-10 and Rv2031 Antigens Varies in Patients With Culture-Confirmed Pulmonary Tuberculosis, Healthy Mycobacterium tuberculosis-Infected and Non-Infected Individuals in a Tuberculosis Endemic Setting, Ethiopia, Scandinavian Journal of Immunology 78(3): 266-274.
- Sutherland, J.S.; Lalor, M.K.; Black, G.F.; Ambrose, L.R.; Loxton, A.G.; Chegou, N.N.; Kassa, D.; Mihret, A.; Howe, R.; Mayanja-Kizza, H.; Gomez, M.P.; Donkor, S.; Franken, K.; Hanekom, W.; Klein, M.R.; Parida, S.K.; Boom, W.H.; Thiel, B.A.; Crampin, A.C.; Ota, M.; Walzl, G.; Ottenhoff, T.H.M.; Dockrell, H.M.; Kaufmann, S.H.E. & GCGH Biomarkers TB Consortium (2013), Analysis of Host Responses to Mycobacterium tuberculosis Antigens in a Multi-Site Study of Subjects with Different TB and HIV Infection States in Sub-Saharan Africa, PLoS ONE 8(9).
- Welten, S.P.M.; Redeker, A.; Franken, K.L.; Benedict, C.A.; Yagita, H.; Wensveen, F.M.; Borst, J.; Melief, C.J.M.; Lier, R.A.W. van; Gisbergen, K.P.J.M. van & Arens, R. (2013), CD27-CD70 Costimulation Controls T Cell Immunity during Acute and Persistent Cytomegalovirus Infection, Journal of Virology 87(12): 6851-6865.
- Singh, S.K.; Tummers, B.; Schumacher, T.N.; Gomez, R.; Franken, K.L.M.C.; Verdegaal, E.M.; Laske, K.; Gouttefangeas, C.; Ottensmeier, C.; Welters, M.J.P.; Britten, C.M. & Burg, S.H. van der (2013), The development of standard samples with a defined number of antigen-specific T cells to harmonize T cell assays: a proof-of-principle study, Cancer Immunology, Immunotherapy 62(3): 489-501.
- Commandeur, S.; Meijgaarden, K.E. van; Prins, C.; Pichugin, A.V.; Dijkman, K.; Eeden, S.J.F. van den; Friggen, A.H.; Franken, K.L.M.C.; Dolganov, G.; Kramnik, I.; Schoolnik, G.K.; Oftung, F.; Korsvold, G.E.; Geluk, A. & Ottenhoff, T.H.M. (2013), An Unbiased Genome-Wide Mycobacterium tuberculosis Gene Expression Approach To Discover Antigens Targeted by Human T Cells Expressed during Pulmonary Infection, Journal of Immunology 190(4): 1659-1671.
- Kassa, D.; Ran, L.; Geberemeskel, W.; Tebeje, M.; Alemu, A.; Selase, A.; Tegbaru, B.; Franken, K.L.M.C.; Friggen, A.H.; Meijgaarden, K.E. van; Ottenhoff, T.H.M.; Wolday, D.; Messele, T. & Baarle, D. van (2012), Analysis of Immune Responses against a Wide Range of Mycobacterium tuberculosis Antigens in Patients with Active Pulmonary Tuberculosis.
- Bobosha, K.; Tang, S.T.; Ploeg-van Schip, J.J. van der; Bekele, Y.; Martins, M.V.S.B.; Lund, O.; Franken, K.L.M.C.; Khadge, S.; Pontes, M.A.D.; Goncalves, H.D.; Hussien, J.; Thapa, P.; Kunwar, C.B.; Hagge, D.A.; Aseffa, A.; Pessolani, M.C.V.; Pereira, G.M.B.; Ottenhoff, T.H.M. & Geluk, A. (2012), Mycobacterium leprae virulence-associated peptides are indicators of exposure to M. leprae in Brazil, Ethiopia and Nepal, Mem�rias do Instituto Oswaldo Cruz. 107: 112-123.
- Geluk, A.; Eeden, S.J.F. van den; Meijgaarden, K.E. van; Dijkman, K.; Franken, K.L.M.C. & Ottenhoff, T.H.M. (2012), A multistage-polyepitope vaccine protects against Mycobacterium tuberculosis infection in HLA-DR3 transgenic mice, Vaccine 30(52): 7513-7521.
- Abreu, J.R.F.; Martina, S.; Stuart, A.A.V.; Fillie, Y.E.; Franken, K.L.M.C.; Drijfhout, J.W. & Roep, B.O. (2012), CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity, Clinical and Experimental Immunology 170(1): 57-65.
- Chegou, N.N.; Essone, P.N.; Loxton, A.G.; Stanley, K.; Black, G.F.; Spuy, G.D. van der; Helden, P.D. van; Franken, K.L.; Parida, S.K.; Klein, M.R.; Kaufmann, S.H.E.; Ottenhoff, T.H.M. & Walzl, G. (2012), Potential of Host Markers Produced by Infection Phase-Dependent Antigen-Stimulated Cells for the Diagnosis of Tuberculosis in a Highly Endemic Area, PLoS ONE 7(6): -.
- Geluk, A.; Bobosha, K.; Ploeg-van Schip, J.J. van der; Spencer, J.S.; Banu, S.; Martins, M.V.S.B.; Cho, S.N.; Franken, K.L.M.C.; Kim, H.J.; Bekele, Y.; Uddin, M.K.M.; Hadi, S.A.; Aseffa, A.; Pessolani, M.C.V.; Pereira, G.M.B.; Dockrell, H.M. & Ottenhoff, T.H.M. (2012), New Biomarkers with Relevance to Leprosy Diagnosis Applicable in Areas Hyperendemic for Leprosy, Journal of Immunology 188(10): 4782-4791.
- Riano, F.; Arroyo, L.; Paris, S.; Rojas, M.; Friggen, A.H.; Meijgaarden, K.E. van; Franken, K.L.M.C.; Ottenhoff, T.H.M.; Garcia, L.F. & Barrera, L.F. (2012), T cell responses to DosR and Rpf proteins in actively and latently infected individuals from Colombia.
- Romano, M.; Aryan, E.; Korf, H.; Bruffaerts, N.; Franken, C.L.M.C.; Ottenhoff, T.H.M. & Huygen, K. (2012), Potential of Mycobacterium tuberculosis resuscitation-promoting factors as antigens in novel tuberculosis sub-unit vaccines.
- Chegou, N.N.; Black, G.F.; Loxton, A.G.; Stanley, K.; Essone, P.N.; Klein, M.R.; Parida, S.K.; Kaufmann, S.H.E.; Doherty, T.M.; Friggen, A.H.; Franken, K.L.; Ottenhoff, T.H. & Walzl, G. (2012), Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting, BMC Infectious Diseases 12: -.
- Pena, M.; Geluk, A.; Ploeg-van Schip, J.J. van der; Franken, K.L.M.C.; Sharma, R. & Truman, R. (2011), Cytokine responses to Mycobacterium leprae unique proteins differentiate between Mycobacterium leprae infected and naive armadillos, Leprosy Review 82(4): 422-431.
- Lahiri, R.; Randhawa, B.; Franken, K.L.M.C.; Duthie, M.S.; Spencer, J.S.; Geluk, A. & Krahenbuhl, J.L. (2011), Development of a Mouse Food Pad Model for Detection of Sub Clinical Leprosy, Leprosy Review 82(4): 432-444.
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