Bernardus Hierck
- Name
- Dr. B.P. Hierck
- Telephone
- +31 71 526 6692
- b.p.hierck@lumc.nl
- Faculteit Geneeskunde
- Divisie 4
- Anatomie en Embryologie
- Bogomolova, K.; Vorstenbosch, M.A.T.M.; Messaoudi, I. el; Holla, M.; Hovius, S.E.R.; Hage, J.A. van der & Hierck, B.P. (2022), Effect of binocular disparity on learning anatomy with stereoscopic augmented reality visualization, Anatomical Sciences Education 16(1).
- (2021), Development of a patient-oriented Hololens application to illustrate the function of medication after myocardial infarction .
- (2021), Design and implementation of "AugMedicine: lung cases", Frontiers in Virtual Reality 1.
- Seghers, L.; Vries, M.R. de; Pardali, E.; Hoefer, I.E.; Hierck, B.P.; Dijke, P. ten; Goumans, M.J. & Quax, P.H.A. (2012), Shear induced collateral artery growth modulated by endoglin but not by ALK1, Journal of Cellular and Molecular Medicine 16(10): 2440-2450.
- Poelma, C.; Kloosterman, A.; Hierck, B.P. & Westerweel, J. (2012), Accurate Blood Flow Measurements: Are Artificial Tracers Necessary?, PLoS ONE 7(9): -.
- Egorova, A.D.; Heiden, K. van der; Poelmann, R.E. & Hierck, B.P. (2012), Primary cilia as biomechanical sensors in regulating endothelial function, Differentiation 83(2): S56-S61.
- Dijke, P. ten; Egorova, A.D.; Goumans, M.J.T.H.; Poelmann, R.E. & Hierck, B.P. (2012), TGF-beta Signaling in Endothelial-to-Mesenchymal Transition: The Role of Shear Stress and Primary Cilia, Science Signaling 5(212): -.
- Dijke, P. ten; Egorova, A.D.; Goumans, M.J.T.H.; Poelmann, R.E. & Hierck, B.P. (2012), TGF-β signaling in endothelial-to-mesenchymal transition: the role of shear stress and primary cilia., Science Signaling 5(212): pt2.
- Egorova, A.D.; DeRuiter, M.C.; Boer, H.C. de; Pas, S. van de; Gittenberger-de Groot, A.C.; Zonneveld, A.J. van; Poelmann, R.E. & Hierck, B.P. (2012), Endothelial colony-forming cells show a mature transcriptional response to shear stress, In Vitro Cellular and Developmental Biology - Animal 48(1): 21-29.
- Egorova, A.D.; DeRuiter, M.C.; Boer, H.C. de; Pas, S. van de; Gittenberger-de Groot, A.C.; Zonneveld, A.J. van; Poelmann, R.E. & Hierck, B.P. (2012), Endothelial colony-forming cells show a mature transcriptional response to shear stress.
- Egorova, A.D.; Khedoe, P.P.S.J.; Goumans, M.J.T.H.; Yoder, B.K.; Nauli, S.M.; Dijke, P. ten; Poelmann, R.E. & Hierck, B.P. (2011), Lack of Primary Cilia Primes Shear-Induced Endothelial-to-Mesenchymal Transition, Circulation Research 108(9): 1093-U142.
- Egorova, A.D.; Khedoe, P.P.S.J.; Goumans, M.J.T.H.; Nauli, S.M.; Dijke, P. ten; Poelmann, R.E. & Hierck, B.P. (2011), Lack of Primary Cilia Primes Shear-Induced Endothelial-to-Mesenchymal Transition, Circulation Research 108(9): 1093U142.
- Egorova AD, Van der Heiden K, Van de Pas S, Vennemann P, Poelma C, DeRuiter MC, Goumans MJ, Gittenberger-de Groot AC, ten Dijke P, Poelmann RE & Hierck BP. (2011), Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells., Developmental Dynamics.
- Alkemade, F.E.; Vliet, P. van; Henneman, P.; Dijk, K.W. van; Hierck, B.P.; Munsteren, J.C. van; Scheerman, J.A.; Goeman, J.J.; Havekes, L.M.; Gittenberger-de Groot, A.C.; Elsen, P.J. van den & DeRuiter, M.C. (2010), Prenatal Exposure to apoE Deficiency and Postnatal Hypercholesterolemia Are Associated with Altered Cell-Specific Lysine Methyltransferase and Histone Methylation Patterns in the Vasculature, American Journal of Pathology 176(2): 542-548.
- Poelma, C.; Heiden, K. van der; Hierck, B.P.; Poelmann, R.E. & Westerweel, J. (2010), Measurements of the wall shear stress distribution in the outflow tract of an embryonic chicken heart, Interface 7(42): 91-103.
- Rossi M, Lindken R, Hierck BP & Westerweel J (2009), Tapered microfluidic chip for the study of biochemical and mechanical response at subcellular level of endothelial cells to shear flow, Lab on a Chip 9(10): 1403-1411.
- Poelmann RE, Groot ACGD & Hierck BP (2008), The development of the heart and microcirculation: role of shear stress, Medical and Biological Engineering and Computing 46(5).
- Hierck BP, Van der Heiden K, Alkemade FE, de Pas SV, Van Thienen JV, Groenendijk BCW, Bax WH, Van der Laarse A, DeRuiter MC, Horrevoets AJG & Poelmann RE (2008), Primary cilia sensitize endothelial cells for fluid shear stress, Developmental Dynamics 237(3).
- Van der Heiden K, Hierck BP, Krams R, de Crom R, Cheng C, Baiker M, Pourquie MJBM, Alkemade FE, DeRuiter MC, Gittenberger-de Groot AC & Poelmann RE (2008), Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis, Atherosclerosis 196(2).
- Hierck BP, Van der Heiden K, Poelma C, Westerweel J & Poelmann RE (2008), Fluid shear stress and inner curvature remodeling of the embryonic heart. Choosing the right lane!, Scientific World Journal 8.
- Groenendijk BCW, Stekelenburg-de Vos S, Vennemann P, Wladimiroff JW, Nieuwstadt FTM, Lindken R, Westerweel J, Hierck BP, Ursem NTC & Poelmann RE (2008), The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo, Journal of Vascular Research 45(1).
- Cheng C, Helderman F, Tempel D, Segers D, Hierck B, Poelmann R, van Tol A, Duncker DJ, Robbers-Visser D, Ursem NTC, van Haperen R, Wentzel JJ, Gijsen F, van der Steen AFW, de Crom R & Krams R (2007), Large variations in absolute wall shear stress levels within one species and between species, Atherosclerosis 195(2).
- Groenendijk BCW, Van der Heiden K, Hierck BP & Poelmann RE (2007), The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous Ligation model, Physiology 22(6).
- Helderman F, Segers D, de Crom R, Hierck BP, Poelmann RE, Evans PC & Krams R (2007), Effect of shear stress on vascular inflammation and plaque development, Current Opinion in Lipidology 18(5).
- Hierck BP, van der Heiden K, DeRuiter MC, Gittenberger-de Groot AC & Poelmann RE (2007), Fluid shear stress controls cardiovascular development. A functionomic approach, Wiener Klinische Wochenschrift 119.
- Van der Heiden K, Groenendijk BCW, Hierck BP, Hogers B, Koerten HK, Mommaas AM, Gittenberger-de Groot AC & Poelmann RE (2006), Monocilia on chicken embryonic endocardium in low shear stress areas, Developmental Dynamics 235(1).
- Vennemann P, Kiger KT, Lindken R, Groenendijk BCW, Stekelenburg-de Vos S, ten Hagen TLM, Ursem NTC, Poelmann RE, Westerweel J & Hierck BP (2006), In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart, Journal of Biomechanics 39(7).
- Groenendijk BCW, Hierck BP, Vrolijk J, Baiker M, Pourquie MJBM, Gittenberger-de Groot AC & Poelmann RE (2005), Changes in shear stress-related gene expression after experimentally altered venous return in the chicken embryo, Circulation Research 96(12).
- Hierck BP, Witte B, Poelmann RE, Gittenberger-de Groot AC & Gittenberger E (2005), Chirality in snails is determined by highly conserved asymmetry genes, Journal of Molluscan Studies 71.
- Hierck BP, Molin DGM, Boot MJ, Poelmann RE & Groot ACGD (2004), A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region, Pediatric Research 56(3).
- Groenendijk BCW, Hierck BP, Gittenberger-de Groot AC & Poelmann RE (2004), Development-related changes in the expression of shear stress responsive genes KLF-2, ET-1, and NOS-3 in the developing cardiovascular system of chicken embryos, Developmental Dynamics 230(1).
- Boot MJ, Gittenberger-de-groot AC, van Iperen L, Hierck BP & Poelmann RE (2003), Spatiotemporally separated cardiac neural crest subpopulations that target the outflow tract septum and pharyngeal arch arteries, Anatomical Record 275A(1).
- Molin DGM, Bartram U, Van der Heiden K, Van Iperen L, Speer CP, Hierck BP, Poelmann RE & Gittenberger-De-Groot AC (2003), Expression patterns of Tgf beta 1-3 associate with myocardialisation of the outflow tract and the development of the epicardium and the fibrous heart skeleton, Developmental Dynamics 227(3).
- Yamagishi C, Hierck BP, Gittenberger-de Groot AC, Yamagishi H & Srivastava D (2003), Functional attenuation of Ufd1l, a 22q11.2 deletion syndrome candidate gene, leads to cardiac outflow septation defects in chicken embryos, Pediatric Research 53(4).
- Deruiter MC, Rensen SSM, Coolen GPGM, Hierck BP, Bergwerff M, Debie WMH, Gittenberger-De Groot AC & Van Eys GJJM (2001), Smoothelin expression during chicken embryogenesis: Detection of an embryonic isoform, Developmental Dynamics 221(4).
- van Gijn ME, Blankesteijn WM, Smits JFM, Hierck B & Gittenberger-de Groot AC (2001), Frizzled 2 is transiently expressed in neural crest-containing areas during development of the heart and great arteries in the mouse, Anatomy and Embryology 203(3).