Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…

As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.

This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…

A high performance computer or supercomputer owes its massive processing capacity to the fact that it chops a single overarching task into a whole series of smaller tasks. It simultaneously tackles each of those smaller problems.

Leiden University offers the possibility of pursuing a doctorate in the form of a ‘double doctorate’: a doctorate that is completed simultaneously at two or more universities. This can either lead to a joint doctoral degree (one single diploma awarded by both institutions) or a double doctorate (each…

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

On the 23rd of February, Adrian Sydney Gomes successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Adrian on this achievement!

The Astronomy Research specialisation includes various advanced astronomy courses that you can choose from each year.

The focus of the Multicriteria Optimization and Decision Analysis (MODA) group is to develop foundations of methods in multi-objective optimization.

Is there a causal mechanism underlying the decision to attack another country when on the brink of war? If so, does this mechanism differ between regime-types? Political scientist Femke Bakker (Leiden University) addresses this question from a political psychological and comparative perspective and…

Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

The recent rise in global migration movements and the simultaneous attempts to prevent migrations to the Global North in general and Europe in particular have produced numerous images and narratives that try to record and convey these events and their actors.

Assistant Professor at the Department of Analytical Chemistry, Radboud University Nijmegen, the Netherlands

Investigating the relations between Tupi Indigenous Knowledge, Museum Collections and the Dutch Colonization of Brazil

The book Global Gold Production Touching Ground: Expansion, Informalization, and Technological Innovation is edited by Boris Verbrugge and Sara Geenen. In recent decades, gold mining has moved into increasingly remote corners of the globe. Aside from the expansion of industrial gold mining, many countries…

Immigrants in the Sexual Revolution. Perceptions and Participation in Northwest Europe. Andrew Shield

The Astronomy and Instrumentation courses go beyond astronomy and space applications to enable you to use your knowledge and skills in adjacent areas of science and technology, including the development of instrumentation for environmental and medical applications.

The Astronomy and Data Science master’s programme offers a coherent combination of relevant courses from the Astronomy and Computer Science curricula and two hands-on research projects.

You have ample opportunity to assemble your own study path in Cosmology. The courses cover the full spectrum from theoretical early universe to observational cosmology.

Evert Jan van Leeuwen’s entry in Auteur Press’s Devil's Advocate series provides a complete study of the aesthetic appeal of Roger Corman's influential first Poe picture House of Usher.

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.

PhD defence

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

The new sports centre will be a sustainable building. It will be used as an examination location as well.

This volume offers a multidisciplinary view of cutting-edge research on bilingualism in Spanish and Portuguese-speaking regions, with the aim of building a bridge between sub-fields and approaches that often find themselves isolated from one another.

Promotor: Roeland M.H. Merks

Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

On 8 January 2020, Jelmer Brouwer defended his thesis 'Detection, detention, deportation'. The doctoral research was supervised by Prof. J.P. van der Leun and Prof. M.A.H. van der Woude.

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Promotor: R. Gill, Co-promotor: P. Massart

Can we develop a generic method for Quan/Qual analysis of small molecule drugs, their metabolites and endogenous metabolites in (pre-)clinical samples?

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

In modern information systems, a large number of different components are often active simultaneously. This phenomenon - known as concurrency - underlies not only the functioning of computer systems but of any system in which many processes take place at the same time.

Would you like to take on an extra challenge during your LUC programme? You can combine your LUC programme with studying at the Academy of Creative and Performing Arts (ACPA) or do a Double Degree Study with the Faculty of Law of Leiden University.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

How are law and governance in China responding to rapidly changing circumstances, and what does that mean for the relationship between the state and its citizens?

Commagene in its Local, Regional and Global Hellenistic Context

Jeffrey Kotyk defended his thesis on 7 September 2017

This dissertation derives from the development of tools for algorithmic composition which extract pitch materials from sound signals, analyzing them according to their timbral and harmonic properties, putting them into motion through diverse rhythmic and textural procedures.

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

Stakeholder engagement practices are on the rise in regulatory governance. This raises an important question regarding implications for regulatory legitimacy. Engagement mechanisms are not by default legitimizing: Even when initiated to tap into an array of ‘benevolent’ desiderata, unless carefully…

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Proceedings of the Vth International Conference of Isis Studies, Boulogne-sur-Mer, October 13-15, 2011

This ethnographic exploration of anticipation published in the Journal of the Royal Anthropology Institute draws on fieldwork among people with dementia and their families in the Netherlands.

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.