Wij richten ons op natuurlijke producten van onderzoek, de traditionele geneeskunde, etnobotanie en fytochemie.

Creating information portals for support of European environmental policy.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

Development of an aggregated impact indicator to measure decoupling.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

In this thesis we study products of linear error correcting codes.

Promotor: Prof.dr. J.P. Abrahams

Met Natural Computing worden natuurlijke algoritmes en verschijnselen onderzocht om bijvoorbeeld computersystemen te innoveren.

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

ENVIRHUS (Environmental and Rural History of Urbanized Societies) organiseert op 17 februari 2023 (14u-17u) de workshop ‘The Natural World‘.

Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.

To deliver a Virtual Sensor tool optimised to exploit the synergy between Sentinels 2 and 3 to allow the consistent retrieval of land surface parameters (Albedo, LAI, and LST); To extend the existing capabilities of land EO data assimilation tools to add capacity to handle data in the thermal domain…

Arts and leisure, Arts and leisure

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

Science, Leiden Institute of Advanced Computer Science (LIACS)

Science, Leiden Academic Centre for Drug Research (LACDR)

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

Promotor: Prof.dr. G.R. de Snoo

Science, Institute of Environmental Sciences (CML)

How can we, together international experts, define future needs of R+D contributions for innovations in the field of risk-based management of chemicals and products in a global perspective using alternative testing strategies to minimize animal tests?

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Het onderzoeksgebied Natural Computing is uitgegroeid tot een onderzoeksgebied met een spannende interactie tussen informatica en natuurwetenschappen en een belangrijke katalysator voor deze twee-weg interactie. Dit driedelige handboek van meer dan 2000 pagina's is een belangrijk verslag van deze belangrijke…

Science, Institute of Biology Leiden (IBL)

What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?

PhD defence

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotor: Prof.dr. G.P. van Wezel

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

Science, Institute of Biology Leiden (IBL)

We leveren fenotypische read- outs voor diagnose en patiënt stratificatie voor een behandeling op basis van innovatieve metabolomics, UPE en organ-on-a-chip technologie. Met een farmacologische én biologische aanpak bieden we inzicht in ziektemechanismen en vertalen dat voor de gepersonaliseerde gen…

Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu

Multi-criteria optimalisatie is een effectieve techniek voor het vinden van optimale oplossingen die een afweging bieden tussen verschillende, tegenstrijdige criteria. Het heeft zijn toepassing gevonden in de wereld om ons heen omdat bij het oplossen van praktische, re¨ele wereld problemen men gewoonlijk…

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

Natural language processing, een type van kunstmatige intelligentie, wordt na jaren van ontwikkelingen toegepast op wetenschappelijke vakgebieden buiten de informatica. Suzan Verberne werkt al jaren aan natural language processing, en vertelt in De Volkskrant over enkele van haar projecten.

Promotor: Robert Tijdeman, Co-promotor: Cornelis Kraaikamp