Koper

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…

Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Engineered nanomaterials (ENMs) are widely used, and nanotechnological innovations grow with rapid pace. Studies on nanotoxicology have demonstrated that chemical toxicology as well as particle toxicology should be accounted for in predicting the safety of ENMs.

Complex Structures Made Simple - Continuous Flow Production of Core Cross-Linked Polymeric Micelles for Paclitaxel Pro-Drug-Delivery

Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).

The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors

Although exposure therapy is the gold-standard treatment of posttraumatic stress-disorder (PTSD), only half of the patients adequately benefit from it. Based on recent insights into the mechanisms of extinction, this project examines strategies and techniques to improve exposure treatment outcome in…

PhD defence

Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.

Lecture

The Joan Van der Waals colloquium is an ongoing bi-weekly lecture series.

What is the effect of pesticides, fertilizers or plastic on water quality? And how do wind and rain affect the data? These are just some of the things that Leiden environmental scientists study in the 32 ditches of the Living Lab.

Recent publications

The central theme of Rik Mom’s research group is to identify what the electrode-electrolyte interface looks like when electrocatalysis is taking place. Using specialized forms of Raman and X-ray spectroscopy, we study the chemical state and bonding environment of the electrode surface and near-surface…

Coordination chemistry is the chemistry of metal atoms

The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…

What is the environmental impact, the human health impact and the life cycle and production costs of the lab, pilot and commercial diffusion of nanowires and nanowire-based photovoltaic technologies?

Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.

Conference

Emeritus professor at the Natural Products Laboratory, Institute of Biology, Leiden University - the Netherlands

Dr. Cátia Antunes and prof. Jos Gommans both edited and contributed to this interesting book, that consists of articles that offers a new insight into the macro and micro worlds of the global Dutchman in Asia.

The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

The master's specialisation Clinical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

Leiden researchers have carried out successful tests using a new method of packaging a cancer vaccine in nano-particles. The new vaccine has induced a strong immune reaction in mice. The researchers believe that this method can make an important contribution to the treatment of cancer. Their findings…

Inviting members of the public to help monitor wildlife, photograph plants or conduct samplings. These are some of the many examples of Citizen Science. It is increasingly recognized as effective and impactful for collecting data, but also for engaging the public in scientific research. In Nature reviews…

Chemical substances and nanomaterials are processed on a massive scale in diverse products, while their risks have not been properly assessed. Time and again synthesised substances have been shown to pollute the environment more than lab tests predicted. This is the warning given by Professor of Ecotoxicology…

Yusen Yu wins the prestigious Graduate Student Prize of the Middle East Medievalists (MEM) with his article

Together with colleagues from the UK (lead), Burkina Faso, Ghana, Uganda, Brazil, Sweden, Germany, and Marjo de Theije of the VU (Amsterdam), Luning has obtained a research grant for the project 'Sustainability Transformations in Artisanal and Small-scale Gold Mining: A Multi-Actor and Trans-Regional…

Mathematics students Pim Spelier and Bob Zwetsloot both won a medal at the International Mathematics Competition for University Students (IMC) 2018 in Bulgaria. Spelier talks about the competition, his preparations, and a mistake that almost costed him his good ranking.

Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.

How do nanoparticles bioaccumulate and biodistribute in organisms?

Three programmes at the Faculty of Humanities have been awarded medals by EW and ResearchNed. The bachelor’s in German Language and Culture took gold, and the bachelor's in Ancient Near Eastern Studies and the master's in Middle Eastern Studies each earned a bronze medal.

Port City Futures is an initiative of the Leiden-Delft-Erasmus Universities collaboration. The program investigates the evolving socio-spatial conditions, use and design of port city regions, in particular exploring areas where port and city activities occur simultaneously and sometimes conflict.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Rembrandt experts have been puzzling over this painting from 1626 for years. The work may have been commissioned by someone from University circles and may depict a judgment. It can be seen at Gravensteen, a building that served as a prison between 1463 and 1955. This historical building later became…

Within the Global Ethnography specialisation, you can develop your own research project or make use of the research opportunities offered by our staff members listed below.

In tracing intra-site, local and regional craft networks in Late Bronze Age Tiryns (Greece) the project aimed to understand technological changes, (dis)continuities and social practices from the Late Palatial until the Post Palatial periods in Mycenaean Greece.

A full overview of MCBIM PhD theses.

Cultural anthropology development sociology, visual methods, policy in practice, global ethnography.

On 12th July 2016, Wim Voermans spoke in the ZDF-heute documentary 'Glamour, Gold und die Liebe: Europas Königshäuser'

Vijf opleidingen van de Leidse rechtenfaculteit hebben een medaille ontvangen als ‘beste studie’. Dit blijkt uit onderzoek dat EW Magazine uitvoerde in samenwerking met ResearchNed. De Advanced Master Air and Space Law scoorde uitzonderlijk hoog en ontving een gouden medaille.

Studying abroad is about more than just your study programme. Laura Noordermeer is on an exchange in Seoul, South Korea, where she was lucky enough to see Suzanne Schulting win the very first gold medal for the Netherlands in the short track.

Not one, but two Olympic rowing medals with a Leiden-Delft touch. Master student Life, Science and Technology Stef Broenink won silver in the double pair. He and partner Melvin Twellaar were in front for a long time, but were overtaken by the French at the last minute.

Just a few weeks until a festival full of exciting science activities bursts into life in Leiden. From January the city will be European City of Science for 365 days. Many researchers are enthusiastic participants. ‘I see it as an opportunity to help people feel the joy of discovering something new…