Lecture

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

In the Catalysis and Surface Chemistry group, we investigate how catalysis works on the molecular level. The group is divided in six subgroups, focusing on different aspects of heterogeneous catalysis, homogeneous catalysis and electrocatalysis.

PhD defence

PhD defence

PhD defence

PhD defence

Conference, Virtual Exhibition

Formulation of biopharmaceuticals

When did the Mali Empire disintegrate? What does the Sunjata heritage demonstrate about the political situation after 1600?

Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

Lecture

Chiodo

Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Global Challenges is the research programme of the Leiden Institute of Cultural Anthropology and Development Sociology.

PhD defence

Current research at the Skin Barrier and Vaccination group.

The sessions of the workshop will cover various topics, mainly related to operando studies of the structure and the reactivity of a large range of catalytic tailored materials, including model surfaces, well-defined supported nanoparticles and electrochemical systems.

Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

In this study, we evaluated the influence of supercritical carbon dioxide (scCO2) spray drying conditions, in the absence of organic solvent, on the ability to produce dry protein/trehalose formulations at 1:10 and 1:4 (w/w) ratios.

Key publications of the Skin Barrier and Vaccination group.

Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Aimee Boyle, Lars Jeuken and Anne Wentink.

Vaccination via the skin or the mucosae

Speakers that have accepted to participate:

PhD defence

Visualising cell proteins without invasive techniques is possible with the help of fluorescence. During a lecture of the Natuurwetenschappelijk Gezelschap Leiden on 18 January, winner of the Spinoza Prize 2017 and founder of the field of single molecule optics Michel Orrit explained how this works.

Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?

An overview of the research at the Biologics Formulation group

This research group is interested in the physics of living cells, especially their cytoskeleton dynamics under defined external stimuli.

On Thursday November 15th, Leiden University organizes its Physics & Astronomy Ladies' Day for female high school students. To mark this festive day, we put the spotlight on five female researchers, who talk about their experiences working in science.

On 1 August, Lars Jeuken started work as Professor of Biophysical Chemistry at the Leiden Institute of Chemistry (LIC). His research is at the intersection of biology and chemistry, but also involves physics and nanotechnology. Jeuken: ‘By linking nanoparticles to proteins and bacteria, we want to convert…

PhD defence

Lecture

Mathilde Mechling defended her thesis on 28 january 2020.

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Koper

The role of material culture in early colonial encounters in the Caribbean