The large-scale project NanoInformatics will assess the risks associated with nanoparticles. The project will be funded by the EU with 6.8 million euros and was launched at the beginning of this year. Three scientists from Leiden are involved. 'For the first time, this project combines the various experts…

Nanoplastics influence the behaviour of larval zebrafish, says new research by the Institute of Biology Leiden (IBL) and the Institute of Environmental Sciences (CML). The researchers observed that a certain type of nanoparticles leads to stress reactions in the sugar balance, resulting in hyperactivity…

Professor of Ecotoxicology Martina Vijver of the Institute of Environmental Sciences has given a public talk at Paradiso Amsterdam for Science & Cocktails on 4 March 2019. Her presentation was called: 'The added value & added risk of size: nanomaterials'.

On Tuesday 4 September, Martina Vijver delivered the scientific lecture during the academic opening of the Faculty of Science. Martina is professor in Ecotoxicology at CML and would like to have collaborations with colleagues from the Leiden Centre of Data Science. We had a brief interview with her.

Nanoparticles are widely used, but their effect on the environment is unclear because they are hard to track. Leiden physicists have developed a new method to detect conducting nanoparticles. Aquiles Carattino successfully defended his PhD thesis on the subject.

How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…

Leiden PhD student Xuequan Zhou has designed a new promising molecule that efficiently kills cancer cells, but does not harm healthy tissue. The trick: the drug is only active when irradiated with light. Zhou’s new compound does this extra efficiently by cleverly self-organising into nanoparticles.…

Gold nanoparticles give us a better understanding of enzymes and other molecules. Biswajit Pradhan, PhD candidate at the Leiden Institute of Physics, uses gold nanorods to study individual molecules that would be challenging to detect otherwise. Resulting knowledge can be applied to many research fields,…

During the prestigious International Mathematics Competition in Blagoëvgrad, Burgary, the Leiden University team won one golden and four silver medals. The team included maths students Bob Zwetsloot, Daan van Gent, Onno Berrevoets, Pim Spelier and Wessel van Woerden.

Tiny selenium particles could have a therapeutic effect on ischemic brain strokes by promoting the recovery of brain damage. Pharmacologists, including Alireza Mashaghi from the Leiden Academic Centre for Drug Research discovered that selenium nanoparticles inhibit molecular mechanisms that are responsible…

This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique…

‘Solar panels, toothpaste and sport socks. What do these things have in common?’ Martina Vijver, professor of ecotoxicology begins her TEDx-talk. Watch her online lecture if you want to learn more about the effects of nano-particles on our environment and health.

The virtual Exhibition Gold Matters is now live and can be explored online. This exhibition is the result of collaborations between artists, members of mining communities, and researchers of the Gold Matters’ project. Curating the exhibition is a collaborative effort of the Gold Matters Team with Sabine…

Minute nanoparticles are bringing about a completely new industrial revolution. But little is known about the possible dangers to the food chain. An international group will be examining this issue, and Leiden researchers will be playing a key role.

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.

Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.

Alumna Esmée Winkel, scientific illustrator and botanical artist, has been awarded a gold medal by the British Royal Horticultural Society for a series of six watercolours.

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

If it’s up to PhD student Guangsheng Du, patients don’t need to worry about big needles anymore. At the Leiden Academic Center for Drug Research (LACDR), he studied the use of microneedles and nanoparticles as a new vaccination system. ‘I want to create a more patient-friendly delivery method.’ He defends…

Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

Physicists Lucia Bossoni and Martina Huber have been awarded an NWA Ideeëngenerator-grant for research into iron nanoparticles in the brain. These nanoparticles may be linked to air pollution and Alzheimer's disease.

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.

An international and multi-disciplinary research consortium spent two days at Leiden University for the launch of their ‘GOLD MATTERS’ project, funded jointly by NORFACE and Belmont Forum. The project 'Sustainability Transformations in Artisanal and Small-scale Gold Mining: A Multi-Actor and Trans-Regional…

Using a clever experiment, PhD candidate Shengxiang Yang discovered how gold electrodes convert water into oxygen. He is the first to unravel the mechanism of this reaction. Yang published his results in the journal ACS Catalysis.

In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.

This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.

Dirk Uittenbogaard, a student on the Delft-Leiden Master’s in Industrial Ecology, has won a gold medal for rowing at the Olympic Games in Tokyo. Uittenbogaard took gold in the men’s quadruple sculls, together with Abe Wiersma, Tone Wieten and Koen Metsemakers.

Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…

In October 2021 the Volkskrant published the article 'Rond de bloedgoudmijnen van Burkina Faso heerst de angst voor terreur' (Around the blood-gold mines of Burkina Faso, the fear of terror rules). In this report Carlijne Vos describes how Burkina Faso is rapidly destabilising. The lucrative gold mines…

A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.

How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?

Winning gold in speed skating at the Olympic Games is not just a matter of training hard; data science can also lend a hand. Jeroen van der Eb of the Leiden Institute of Advanced Computer Science (LIACS) developed the measuring skate for this purpose, with which he recently won the Nationale Sportinnovator…

Soil ecologists Emilia Hannula (Leiden) and Elly Morriën (UvA) received the Golden Medal of Teylers Tweede Genootschap on 5 November. They received the prize for their submission to a competition on sustainable soil management.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

The adventure of iGEM Leiden has come to an end. The result: prizes for Best Therapeutic Project and Best Model, a gold medal, a successful crowdfunding campaign and of course their open-source research findings, which are available for the scientific community.

This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals

Promotor: Prof.dr. W. Jiskoot, Co-promotor: A. Kros

Sander Blok has won the third edition of the annual LION Image Award. He created a colorful image of gold nanoparticles with a low-energy electron microscope.

Team Jumbo-Visma is going for gold at the World Championships this weekend in Salt Lake City. For this, they have worked on a new special training method. The Data Mining and Sports group of the Leiden Institute of Advanced Computer Science (LIACS) was involved in the development of this method.

Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.

On Tuesday 4 September, in a full lecture hall C1, Dean Geert de Snoo opened the Academic Year for the Faculty of Science. A year in which the ethics and responsibility of scientists will be invoked.

In an interview on the website of the NWO, Sabine Luning, Marjo de Theije and Esther van de Camp talk about the gold miners they met in various African and South American countries and they come to new insights.

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit.