329 search results for “chronic disease” in the Public website
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Acute and chronic pain after cardiac surgery
Promotores: C.A.J. Knibbe, D. Tibboel, Co-Promotor: P. Bruins
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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candidate “Personalized rewards of lifestyle changes in cardiovascular diseases”
Social and Behavioural Sciences, Psychology
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Chronic obstructive pulmonary disease
PhD Defence
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Systems diagnosis in chronic disease: prediction and evaluation
PhD Defence
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
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Full Professor 'Neuropsychology in Health and Disease'
Social and Behavioural Sciences, Psychology, Health, Medical and Neuropsychology
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Cardiac mechanics in chronic kidney disease
PhD Defence
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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Data-Driven Knowledge Discovery in Polycystic Kidney Disease
PhD Defence
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Risk factors of Chronic Kidney Disease Progression: Dutch Cohort studies
PhD Defence
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
PhD Defence
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Jennifer BeckerFaculteit der Sociale Wetenschappen
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Airway epithelial innate host defence in chronic obstructive pulmonary disease
PhD Defence
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The Iron Brain: Post-mortem and in vivo imaging of iron in brain diseases
PhD Defence
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Investigations on the role of impaired lysosomes of macrophages in disease
PhD Defence
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biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Disease progression and quality of life in chronic kidney disease patients: the role of health behaviour and illness perceptions
PhD Defence
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Mouse models of Chronic Obstructive Pulmonary Disease and Cardiovascular Disease: In search of novel treatment options
PhD Defence
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Sandra van Dijk helpt nierpatiënten gezonder te leven
Hoe kunnen nierpatiënten geholpen worden een gezonde leefstijl aan te nemen? Gezondheidspsycholoog Sandra van Dijk gaat dit onderzoeken met een persoonsgebonden subsidie van de Nierstichting.
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UITGESTELD | Risk factors of Chronic Kidney Disease Progression: Dutch Cohort studies
PhD Defence
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of biomarkers in clinical development of new therapies for chronic airway disease
PhD Defence
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Towards adequate care for sexual health and fertility in chronic kidney disease; perspective of patients, partners and care providers
PhD Defence
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Full professor in Discovery of Biologics
Science, Leiden Academic Centre for Drug Research (LACDR)
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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The power of expectations: Unraveling the role of placebo and nocebo effects in somatic symptoms
Somatic symptoms are highly prevalent and have a major impact on patients and society. This project studies the role of placebo and nocebo effects in the onset, experience, course, and recovery of such somatic symptoms by means of innovative psychological and neurobiological methods and treatments.
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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Macrophage activation and cholesterol in atherosclerosis development
Current therapies for patients with atherosclerosis are targeted primarily on reducing blood cholesterol, but this fails to prevent a large number of cardiovascular events.95 In order to identify new therapeutic strategies for treating atherosclerosis, it is important to study the interactions between…
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Pesticides and health – challenges and opportunities for exposure assessment
The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…
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Transfer of "goods" from plants to humans: Fundamental and applied biochemical investigations on retaining glycosidases
The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.
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Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT)
Description of Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT) (2004 - 2007)
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.