16 search results for “autophagy” in the Public website
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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The role of autophagy during carbon starvation in Aspergillus niger
Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Selective autophagy in host defense against mycobacterial infection
PhD defence
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The role of autophagy during carbon starvation in Aspergillus niger
PhD defence
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
PhD defence
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Opruimactie tegen tuberculose en salmonella-infecties
Het eigen cellulaire recyclesysteem van zebravissen kan schadelijke bacteriën opeten en zo weerstand bieden tegen infecties als tuberculose en salmonellose. Dat schrijven Leidse biologen van de groep van Annemarie Meijer. Het stimuleren van deze vorm van afweer kan gebruikt worden in nieuwe behandelmethoden…
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PhD candidate, The intracellular fate of pathogenic mycobacteria
Science, Institute of Biology Leiden (IBL)
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Post doc, The intracellular fate of pathogenic mycobacteria
Science, Institute of Biology Leiden (IBL)
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Veelbelovend eiwit ontdekt voor nieuwe medicijnen tegen tuberculose
Afweercellen houden tuberculosebacteriën onder controle door ze af te breken. Leids biologe Annemarie Meijer en collega’s ontdekten welk eiwit hiervoor de aanzet geeft. Dat eiwit (DRAM1) is mogelijk geschikt voor nieuwe medicijnen, schrijven ze in Cell Host & Microbe.
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De behandeling van ziekteverwekkende schimmels verbeteren. ‘Het proces werkt wel, maar niet heel goed…’
Schimmels die groeien in de longen van patiënten. Dat klinkt onprettig, toch? Gelukkig kunnen mensen hier normaal prima mee omgaan, en de infectie zelfstandig verhelpen. Maar als er al andere gezondheidsissues spelen, kan Aspergillose wel schade aanrichten. Zeker als de schimmel resistent is tegen antibiotica.…