11 search results for “adhesion” in the Public website
Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
Regulators of integrin α6β4 function
This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.
The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis
In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.
Role of Integrin Adhesions in Cellular Mechanotransduction
Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
Quantitative Super-Resolution Microscopy
Promotor: T. Schmidt
Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
PhD student, to identify and characterize inhibitors of carbohydrate modifying enzymes to generate a new type of anti-viral molecule
Science, Leiden Institute of Chemistry (LIC)
Nieuwe inzichten in de ‘zelfmoord’ van cellen met onherstelbaar beschadigd DNA
Erik Danen en zijn collega-onderzoekers van het Leiden-Academic Centre for Drug Research publiceerden in Science Signaling over nieuwe inzichten in de ‘zelfmoord’ van cellen met onherstelbaar beschadigd DNA. Die inzichten kunnen antwoord geven op de vraag waarom kankercellen het menselijk afweermechanisme…
This Week's Discoveries | 23 May 2017