The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

Can we bring novel treatment options to the clinic for UM patients with liver metastases?

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

The 1st CIGR meeting was held on March 30, 2021, with talks by representatives of all participating groups.

Professor Fons Verbeek of the computer science and biology institutes at Leiden University has the fascination to visualize everything we can not see immediately. At SleutelstadFM he tells us that by converting 2 dimensional (2D) images to 3 dimensional (3D) structures, research is carried out into…

Plants can’t run away from enemies. Still, it would like to keep life-threatening herbivores at a distance. This can be done with odours. Klaas Vrieling of the Institute of Biology Leiden found out with his team how plants change odour production to keep the munchers at a distance.

Tropical butterflies adapt to their environment to improve their chances of survival. The changes are triggered by hormone signals that transmit information about temperature to the butterflies' tissues. Biologist Ana Rita Mateus shows how a complex combination of environment, physiology and genetics…

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

Researchers from all parts of the world will be in Leiden from 2 to 4 May for a major malaria conference. The Leiden University Medical Center (LUMC) is organising a two-day workshop on how vaccines can be tested safely in humans.

He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…

An overview of the research at the Cancer Dug Target Discovery group.

Science, Institute of Biology Leiden (IBL)

Theoretical physicist Helmut Schiessel receives an NWO Projectruimte grant of 390,000 euro. He will use this budget to hire a postdoc and a PhD student to continue his research on flexibility of double stranded DNA.

On Thursday the 24th of November, Tseard Hoekstra and Jeroen Ververs (members of the delegation Holland Rijnland), Geert de Snoo (Dean Faculty of Science), Martina Vijver (CML), Herman Spaink (Scientific Director IBL) and Klaas Vrieling (IBL) explored possibilities for collaborations between companies…

The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.

Martina Vijver has been nominated as Teacher of the Year of the Faculty of Science. She gets this nomination for the course Ecotoxicology she taught in 2022. The 52 students who took the course were hugely enthusiastic, as can be read in their positive reviews. What is so great about this course then?…

The climate crisis, the return of TB and the digitisation of cultural heritage. The Netherlands and Indonesia face many of the same challenges. A visit by a delegation from Leiden University to Indonesia at the end of June highlighted the benefits of cooperation.

Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.

Latin America matters! With its rich history, culture, its impressive resilience and creative innovation in the face of such a diverse array of challenges, Latin America can indeed show the way forward inspiring for positive change. Working together with Latin American institutions, our researchers…

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

During the annual LACDR Spring Symposium, the audience chose PhD student Rob van Wijk as best speaker. Furthermore, six PhD students won a poster prize. Matthias P. Mayer of Heidelberg University opened the symposium with a keynote lecture about chaperone proteins.

The ‘Stans Prize 2018' (for the best thesis, report or article produced by a CML student) has been awarded to Louie Krol. Other CML prizes were awarded to Sebastiaan Deetman and Joris Timmermans.

The latest research from the Leiden outdoor laboratory ‘Living Lab’ shows that the insecticide thiacloprid strongly influences even the most common and robust dragonfly species in the Netherlands. The study was published in the Journal of Applied Ecology.

Coral reefs throughout the world are under threat. After studying the reefs in Malaysia, Zarinah Waheed concluded that there is room for improvement in coral reef conservation. PhD defence 22 November.

Art and science: are they polar opposites? The theme of this year’s Sculptures in Leiden open air exhibition is ‘life sciences’. It has resulted in many intriguing sculptures, including one that is especially endearing.

Martina G. Vijver has been appointed professor of Ecotoxicology at the Institute of Environmental Sciences of Leiden University with effect from 1 December 2017.

Lecture

Symposium

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

The Faculties of Leiden University have developed several themes for research cooperation between Leiden University and its Indonesian partners.

A full overview of BPOC/SSNMR PhD theses.

Crises like climate change and loss of biodiversity threaten our planet. That’s why sustainability is an important topic in research and education across Leiden University. On this website you read how scientists from many disciplines work together in researching sustainability.

Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…

In the week of 22 May, a delegation of the Faculty of Science visited Indonesia to strengthen the cooperation with the Universitas Gadjah Mada, the Universitas Indonesia and the Kebun Raja (botanical garden) in Bogor. Furthermore, the delegation visited the faculty of Pharmacy of the Institut Teknologi…

The first Leiden Science Family Day on Saturday 6 October was a great success. During the ‘Weekend of Science’ more than 700 visitors, including 350 children, visited the Faculty of Science. With a program full of experiments, lectures, guided tours and demonstrations, visitors were given a glimpse…

Early November, a delegation of the Faculty of Science visited two Indonesian universities to shape the collaboration in bioscience. The Faculty also opened a new Indonesian office in Yogyakarta.

Students searched for MSc Internships under the following topics: 1. Understanding temporal variability in functional biodiversity and 2. Characterization of engineered nanoparticles in aquatic organisms: Gold nanoparticles and carbon nanotubes

With a Vici grant of 1.5 million euros, Professor of Mathematical biology Roeland Merks will look for ways to fix messy and leaky blood vessels in tumours. His research combines mathematical simulations and lab experiments in a unique way.

With the necessary measures, researchers restart their work in various laboratories. The Leiden Cell Observatory is one of the places where scientists resume their lab work.

Lecture, Van Leeuwenhoek Lecture on BioScience

Hans Slabbekoorn, researcher at the Institute of Biology Leiden, is from the 16th to the 26th of July on board of the Pelagia, the Dutch national sea research vessel, which is currently on a collaborative mission for the National Initiative Changing Oceans (NICO). Slabbekoorn will study the effects…

Working together, sharing information, communicating and having the same goals. At the official opening on 30 November, biologist Koos Biesmeijer compared Beehive, Leiden University's new student centre in The Hague, with the activities in a real beehive.

PhD defence

Recent publications

‘To be honest, I don’t really care about what type of research is going on. Just let me do my own thing and everything is fine,’ according to biotechnical officer Davy de Witt. In this interview, he tells about his tasks and experiences at the Institute of Biology Leiden, where he has been employed…

Yuven Muniandy (36) from Malaysia recently obtained a PhD from Leiden University. His ‘orientation year’ visa gives him a year to find work in the Netherlands. But with Covid-19, companies have frozen recruitment. Yuven and seven other graduates are asking for a visa extension. He explains why.

Bringing together institutes and research groups, how do you do that? The Faculty of Science set up a joint research theme and financed three PhD positions. After four years, the profiling programme Endocannabinoids expires. ‘It really brought us together, and the collaborations remain.’

Lecture