John van Noort

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

Cell adhesion signaling

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

What is the optimal investment policy according to which a firm adapts its capacity in a competitive market?

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

This research group is interested in the physics of living cells, especially their cytoskeleton dynamics under defined external stimuli.

Developing methodes to understand the evolution of patches in natural ecosystems

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Schemas are knowledge structures that allow us to make efficient judgments about the world without the cost of memorizing every detail of previous experiences. It has long been known that schemas can enhance long-term memory for related information.

Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Science, Institute of Environmental Sciences (CML)

The intracluster medium (ICM) is a hot, tenuous and X-ray emitting gas that pervades galaxy clusters.

Promotor: Prof.dr. G.J. Kroes

This dissertation shows that dialogical logic constitutes a powerful and flexible general framework for the development and study of various logical formalisms and combinations thereof.

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.

Birds sing to be heard, but how do they cope with increasing noise levels? Which species persist in cities and why? And do they thrive or suffer in the urban soundscape?

This work represents the final results of several years of research within the Maya region. It deals with the relations between architecture and urbanism with landscape and astronomy.

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Green infrastrucuture (GI) like urban farm and green roofs could provide many beneficial functions in cities. These include for example food production, flood prevention or increasing biodiversity. MultiGreen project aims at developing an integrated modelling tool to support…

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

This project looks at the ways in which youth in southern Nigeria navigate their lives in a context of experiencing long-term socioeconomic uncertainty and political insecurity (duress).

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

The map application includes information from old and new buildings archaeological projects. This makes it possible to investigate whether water facilities (wells, cisterns) and waste facilities (cesspits, sewers) were the privilege of Leiden’s wealthy elite in the late 16th and 17th centuries or whether…

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

What are the principles of genome folding and dynamics in bacteria?

Isis on the Nile. Egyptian gods in Hellenistic and Roman Egypt

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

Water, Urbanism, and Sustainability in Roman Ostia

The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.

PhD Defence

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

How citizens and professionals are the key to successful collaboration in the delivery of public services. How do individual characteristics of citizens and professionals influence citizen-professional collaboration in the co-production of public services?

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

What was the social function of the colonial civil law courts in eighteenth-century coastal Sri Lanka? Why did people choose to have their disputes settled by Dutch law courts?

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

Lecture, Dean's Lecture

On Wednesday 1 September, the first thirteen students of the new BA Urban Studies at Leiden University, received their diplomas in person in The Hague. During a festive graduation ceremony, they were congratulated by rector magnificus Hester Bijl.

What is the effect of a dynamic training in children’s inductive reasoning skills and how is it related to children’s school performances and language development.

Promotores: F.H.J. Redig, W.T.F. den Hollander