363 search results for “ultra high vacuum” in the Public website
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Unraveling the surface formation of regular and deuterated water in space: a combined laboratory and computational study
Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: H.M. Cuppen, S. Ioppolo
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Leiden Physics hosts 2016 NEVAC day
The Leiden Institute of Physics hosted the annual conference of the Dutch Vacuum Society (NEVAC). Experts in the field of vacuum experiments talked about their research. The 2016 NEVAC Prize was awarded to PhD student Martijn Vos from the TU Eindhoven.
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: H.J.M. de Groot, Co-Promotor: A. Alia
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Laboratory for Astrophysics
We simulate interstellar clouds with special plasma expansions and chemical reactions on icy dust grains to be measured in ultra-high vacuum setups. This provides the data necessary to guide and interpret astronomical observations and to model reaction networks in space. [Harold Linnartz]
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Development of automatic image analysis methods for high-throughput and high-content screening
Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek
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Surface-structure dependencies in catalytic reactions
Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink
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Steps in gas-surface reactions
Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Chemists solve persistent problem after four decades
After almost four decades, Leiden and Eindhoven chemists have resolved the discussion about the correct model for the simplest chemical reaction in heterogeneous catalysis, which is essential for fuel cells. Using a unique curved platinum surface, Ludo Juurlink and PhD candidate Richard van Lent from…
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Operando research in heterogeneous catalysis
The nanoscale structure of a catalyst under reaction conditions determines its activity, selectivity, and stability. For the production of sustainable energy and materials, new catalysts are needed. By understanding the structure-activity relationships of catalysts under reaction conditions, insight…
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of dark matter using the stellar kinematics in the centres of ultra-faint dwarf galaxies
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
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Development of Comprehensive and High-throughput metabolomics techniques
A major goal of ABS research is to overcome one of the major bottle-necks in metabolomic research: the lack of a high-throughput infrastructure in which thousands of samples can be processed in a standardized and cost-effective way (max. a few tens of Euro’s per sample for a full metabolome profile).…
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PhD Theses
A full overview of CASC PhD theses.
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Making cells ultra-heavy
The life of a fibroblast is heavy, but PhD student Julia Eckert makes it 19.5 times heavier, using the Large Diameter Centrifuge at the ESTEC space research centre in Noordwijk.
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Empirical Bayes applications in biomedical high-dimensional prediction
The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.
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High-Contrast Imaging of Protoplanetary Disks
To study how planetary systems come into existence we study much younger systems still in formation.
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High performance computing
A high performance computer or supercomputer owes its massive processing capacity to the fact that it chops a single overarching task into a whole series of smaller tasks. It simultaneously tackles each of those smaller problems.
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Radio galaxies at low frequencies: high spatial and spectral resolution studies with LOFAR
Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley
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Supremacy Scorned? A high-level podcast on the supremacy of EU law after three ultra-vires judgments
Is EU law still supreme? Most national high courts have formulated some limits on the absolute supremacy claimed by EU law.
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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ALICE High Performance Computing facility
High Performance Computing previously the domain of theoretical scientists and computer and software developers is becoming ever more important as a research tool in many research areas. A University facility, providing serious computational capabilities, combined with easy and flexible local access,…
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Ultra-thin material absorbs all the light
It appears to be a paradox: ultra-thin material that absorbs all the incident light. Nonetheless, it does exist. Two Leiden researchers report on their research in ‘Applied Physics Letters’. The article is among the Top 20 of the most downloaded articles of this reputable journal in May.
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The reintegration of high profile ex-offenders
The reintegration of high profile ex-offenders frequently receives great political and public attention. While this attention, more often than not in the form of negative sentiments, may be understandable from a moral perspective, it raises several important questions: how do such offenders reintegrate…
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Strikes the result of high inflation
Employees are laying down their work in various sectors, such as regional public transportation and Dutch postal service PostNL. Inflation appears to be increasing dissatisfaction about working conditions, thinks Barend Barentsen, Professor in Labour Law at Leiden University. ‘It's the final straw.’
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High-throughput screening for developmental and reproductive toxicity
Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?
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High-throughput quantification and unambiguous identification for metabolomics
The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.
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Invited speakers
Speakers that have accepted to participate:
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Astronomers see two planets vacuuming around young star
Astronomers led by Leiden astronomer Sebastiaan Haffert have directly imaged two planets that are gravitationally carving out a wide gap within a planet-forming disk surrounding a young star. While over a dozen exoplanets have been directly imaged, this is only the second multi-planet system to be p…
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High-contrast imaging polarimetry of exoplanets and circumstellar disks
Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken
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ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
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For high school students
We organise various activities for high school students and their physics teachers to learn about Astronomy at Leiden University.
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Silicon pore optics for high-energy optical systems
This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.
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High-resolution integral-field spectroscopy of exoplanets
This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.
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Disorder and interactions in high-temperature superconductors
This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.
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Painting with starlight : optical techniques for the high-contrast imaging of exoplanets
This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.
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Exploring strange new worlds with high-dispersion spectroscopy
Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…
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SKY HIGH: Vertical farming a revolution in plant production
As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.
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Metals in the diffuse gas around high-redshift galaxies
Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Tailored care for children at high risk for problem behaviour
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DAMIOSO - data mining on high volume simulation output
Modern computer-aided simulation tools used by various industries produce gigabytes of data. But currently, they take days and even up to weeks of computation effort. To make the best use of all these data, the DAMIOSO project focuses on developing algorithms and tools for managing, mining, and optimizing…
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Settlement Dynamics and High-Precision 14C Dating
For present purposes, it is important to distinguish between an early period of settlement, about 6800-6200 BC, and a late period, about 6200-5800 BC, at Tell Sabi Abyad.
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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Detection of Archaeological Sites in High Resolution Satellite Images
In this project we develop algorithms to automatically detect a particular type of archaeological sites in satellite images of the Alps.