The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

The ‘right’ amount of dopamine in the brain makes study participants better at solving certain cognitive tasks. This is the conclusion of Bryant Jongkees after experiments and a literature review. PhD defence on 21 February.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

PhD Defence

Promotor: Prof.dr. J. den Hertog

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

Source: Purinergic Signal., Volume 10, Issue 3, pp. 441-53 (2014)

Key publications of the Systems Pharmacology group

Cognitive enhancement reflects the use of any (legitimate) means such as for example food supplements to reach one’s personal best.

During the congress of the Royal Dutch Association for the Advancement of Pharmacy (Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, KNMP) Jacqueline Gerritsen, former student Bio-Pharmaceutical Sciences at Leiden University, was awarded the KNMP student prize.

In a supplementary decision on 17 May 2022, the Executive Board of Leiden University has concluded that it will publish the titles of seven articles in which there is evidence of malpractice. This concerns a former staff member of the Institute of Psychology. The Executive Board considers it to be in…

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…

Lecture

PhD Defence

Overview of Molecular Physiology publications