Bead microrheology: Analysis of active and passive transport in living cells

Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…

This thesis describes a study from both a theoreticaL and an experimental point of view.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

In this thesis, classes of strongly interacting quantum field theories, have been studied.

Promotor: S.M. Verduyn Lunel

Aviation safety is of global concern. Yet 43% of countries worldwide lack the expertise and administrative capacity to ensure effective safety oversight of the aviation activities for which they are responsible under international law.

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?

The territories that would make up what is today the Republic of Zambia officially became British in 1891. However, this did not equate to an on-the-ground presence of colonial authority capable of affecting the destiny and daily lives of people.

Eco-innovations like more economical cars do not generate the environmental benefits predicted by the manufacturers. This is the result of the so-called rebound effect, concludes Leiden industrial ecologist David Font Vivanco on the basis of new algorithms. PhD defence 3 March.

Over the past decades within the European Union (EU), economic proliferation and globalisation have resulted in an increase in transboundary waste transportation. Although waste trading can often have positive economic and environmental impacts by repurposing natural resources within industrial sectors,…

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

On September 10th 2019 Bart Custers, professor of Law & Data Science at eLaw, was invited by the Committee for Infrastructure and Water Management of the Dutch parliament. In a round table discussion, this committee of the House of Representatives wanted to discuss the access to public transport data…

Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…

Meeting in person is crucial to higher education. It would therefore be inadvisable only to allow students to use public transport between 11:00 and 15:00. This is what the rectores magnifici of the Dutch universities say in a joint letter in ScienceGuide.

The winner of the highest scientific distinction in mathematics, an explanation for wine tears and much more mathematical theory and application. From 8 to 12 July, 550 mathematicians will meet in the center of Leiden to discuss differential equations.

Livestock was already transported over long distances in the Bronze Age Netherlands. That is what researchers from Leiden University and VU Amsterdam have discovered. Publication in the Journal of Archaeological Science: Reports.

Promotor: Prof.dr. C.W.J. Beenakker

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

The Leiden Institute of Chemistry (LIC) is to be joined by a further two talented young chemists. Bela Bode and Michele Pavanello have each won a Marie Curie subsidy. Bode will be studying electron transport in photosynthesis and Pavanello will be using computer models to study charge transport in large…

Leiden University, with its 60 locations in Leiden and The Hague, more than 7,300 members of staff, 32,381 students and a large number of visitors, is a dynamic community. Every day thousands of movements take place from, to and between the different University buildings.

A selection of recent publications from the Plant BioDynamics Laboratory.

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

How can the transport of molecules in living cells help to target medicines at exactly the right place?

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…

PhD Defence

Route descriptions to CML by public transport or car

Safety issues of the transport and storage of Chlorine, ammonia and LPG.

Supervisor: Anna Vlachodimou

Plant researchers have been wrong for years about how plant growth and development are regulated, as Yao Xiao pointed out during his PhD project. They overlooked the role of a protein that turns out to be essential, just as it is in the development of animals and yeasts. In plants, it regulates the…

Promotor: A. Kros

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.