Promotor: J.M. Memelink

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

As an Exchange or Study Abroad student you will receive an academic transcript from Leiden University which lists the courses you have passed, with grades and credits obtained.

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Our object is to identify and characterize transcription factors involved in lignocellulosic biomass degradation in the filamentous fungus Aspergillus niger.

Prospective employers sometimes request a certified copy of your diploma or your academic transcript. These certified copies can be provided by the University. You can also apply to the University for advice on having your diploma translated.

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

How does the development of digital technologies impact society, and law/regulation within that society?

For questions about a English diploma statement and/or a transcript in English, you can contact your faculty or the administration of your study.

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

What is the role of memory in contemporary music?

The Faculty Board issued these Regulations of the Institute of Philosophy on 9 January 2018.

What is the role of stress and stress-related hormones in emotion regulation?

More information on the PhD Regulations, Guidelines and Golden Rules.

The role of language in self-regulation and social behavior in children with an extra X chromosome

The PhD regulations set out who is eligible to be a PhD candidate, what the tasks of the supervisor and co-supervisor are and which criteria the dissertation has to meet. The PhD guidelines lay down the minimal requirements for the supervision, training and available facilities for PhD candidates.

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

How do plant defense genes get activated?

How is vegetative development regulated in plants and how does this affect a plant’s life history strategy?

The Leiden Risk & Regulation Lab serves as hub for excellent research in regulation and risk governance and acts a platform for engagement with the practice and education of regulation and risk governance. Specializing in risk governance, responsive and effective regulation, reputation and accounta…

Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior

Procedures en reglementen met betrekking tot de cursussen en diensten van het Academisch Talencentrum. Regulations and procedures regarding courses and services of the Academic Language Centre

How can innovation help or hinder public procurement processes?

The topic of this PhD thesis is teachers' perspectives on self-regulated learning.

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.

This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

The project’s overall goal is to improve Indonesia’s environmental legal framework and its implementation by strengthening the regulatory capacity of the government, and by enhancing the capacity of CSOs and scholars to hold the government accountable for its regulatory performance.

Regulating Relations: Controlling Sex and Marriage

On 28 June 2018, Qiuyin Hu defended his doctoral thesis 'Regulating Working Conditions in Times of Globalization'. The doctoral research was supervised by Prof.dr. G.J.J. Heerma van Voss and Prof. dr. B. Barentsen.

We are all aware of the importance of a healthy lifestyle. However, at the same time we also experience many difficulties when we are trying to change our behavior to become more healthy. For example, more often than not our good intentions to exercise more or to eat fewer unhealthy snacks fail miserably…

On 24 May 2017, the Hazelhoff Centre for Financial Law welcomed Shen Wei, Dean and Professor of law at Shandong University School of Law in China, for the 14th Hazelhoff Guest Lecture.

PhD defence

The data-driven economy allows for the collection and processing of large amounts of data. Such data can be used to optimize profits by (dynamically) differentiating prices for different consumers.

Cardiovascular syndromes are the major cause of death in Western societies.

In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, and Martin Lodge address the question of how to manage banking crises, a question that has gained prominence since the banking crisis of 2007-2009. This article sets out the rationale for regulating for…

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

Promotor: P.M. Brakefield

How does preschoolers’ play style relate to their aggressive impulses?

The expansion of the fund industry has been one of the most notable trends in the financial markets of recent years.