478 search results for “subgroup identification” in the Public website
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: Prof.dr. T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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High-throughput quantification and unambiguous identification for metabolomics
The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Dr. Theo Reijmers
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Identification of novel targets in prostate cancer progression
Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen
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The Palaeoproteomic Identification of Pleistocene Hominin Skeletal Remains:
Towards a Biological Understanding of the Middle to Upper Palaeolithic Transition
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Beyond Dissemination: Hindustani Identifications at the Nexus of Tradition and Modernity
An interdisciplinary cultural analysis of how the Hindustani double migration informs contemporary processes of identification and problematises the juxtaposition of tradition and modernity.
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken
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Towards a better identification of child mental health problems in primary care
PhD Defence
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Identification of productive and futile encounters in an electron transfer protein complex
PNAS publication on protein encounter complexes
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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Computers help wood anatomists with wood identification
The most commonly used method for the taxonomic identification of tree trunks is wood anatomy. The number of experts in this area is decreasing, and education to become an wood anatomists takes many years. With the help of technology computer scientists of the Leiden Institute of Advanced Computer Science…
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Typical representations of GL_n(F)
Promotores: Bas Edixhoven, Guy Henniart
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Ruben HueleScience
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Aad van MastrigtFaculty of Humanities
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Torsion points on elliptic curves over number fields of small degree
Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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Traces of language contact: The Flores-Lembata languages in eastern Indonesia
On the 13th of November, Hanna Fricke successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Hanna on this achievement.
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The unit residue group
The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.
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Intense automorphisms of finite groups
In this thesis we classify the pairs (p,G), where p is a prime number and G is a finite p-group possessing an intense automorphism, i.e. an automorphism that sends each subgroup of G to a G-conjugate, that is non-trivial and whose order is coprime to p.
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Rianne de HeideScience
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Inclusion and exclusion
How do inclusion and exclusion affect people?
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Kimberly EmigScience
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Past research
Read about the impact of past research
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Images of Galois representations
Promotores: S.J. Edixhoven, P.Parent
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A grammar of Ik (Icetod) Northeast Uganda’s last thriving Kuliak language
This study offers a comprehensive but balanced grammatical analysis of Ik (Icetod), Northeast Uganda’s last thriving Kuliak language.
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Bayesian learning: challenges, limitations and pragmatics
This dissertation is about Bayesian learning from data. How can humans and computers learn from data?
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Galois representations of elliptic curves and abelian entanglements
Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Universite Bordeaux I)
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The Historical Sources of the Mali Empire Reconsidered
When did the Mali Empire disintegrate? What does the Sunjata heritage demonstrate about the political situation after 1600?
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Early identification of rheumatoid arthritis
PhD Defence
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ProParte Museumclub
The Museum club is a sub-group of ProParte.
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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ProParte Gymclub
The Gymclub is a sub-group of ProParte.
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Changing minds in social anxiety: A developmental network approach to neurocognitive bias modification
Which adolescents are more at risk of developing social anxiety disorder later in life?
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Screening of animal venoms for antimicrobial compounds
Can animal venoms yield novel antimicrobial peptides?
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Early identification and resolution of rheumatoid arthritis
PhD Defence
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Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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Technologies and social agency of painted plaster in the East Mediterranean Bronze Age
This project explored the role of material culture, in casu painted plaster and its technologies, in expressing dynamic social identities and in forging complex interwoven human relationships in the context of the Middle to Late Bronze Age of the Aegean and East Mediterranean.
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A Grammar of Cheke Holo
On November 21st, Frederick Boswell succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Frederick on this great result.
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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A Grammar of Dhao
On the 17th of September, Jermy Balukh successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Jermy on this achievement!
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Translational drug discovery and development
We cover the entire spectrum from target identification to the evaluation of the efficacy and safety of novel medicines in clinical practice.