In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

We are aiming to develop novel technologies to allow better sample preparation or coupling of analytical methods to (i) analyse ultra small samples, (ii) to analyse more metabolites in a quantitative manner and/or (iii) increase the sample throughput.

PhD Defence

PhD Defence

Metabolomicshas emerged as an important discipline to study molecular and cellular processes in living cells and organisms with the ultimate aim to obtain an answer to a given biological/clinical question.

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We develop open micro cavities to trap light in small volumes and thereby increase the interaction with intra-cavity emitters. Important aspects in this development are the optical penetration in the mirrors, coupling between optical modes, and scattering and clipping losses.

Leiden Embedded & Real-time Computing (LERC) is an expert lab and leader in advanced research on embedded and real-time systems and software. The main mission of LERC is by its research to contribute in a highly innovative way to the system-level design of embedded and cyber-physical systems and software…

This thesis is about cosmological inflation and its relation to observations.

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

In the last couple of decades an ‘animal turn’ has taken place in the social sciences. This has led to a call to study social issues by including non-human animal perspectives. This Collaborative Research Group thinks it's high time that African Studies joins the chorus of minds that try to contribute…

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

As your major strongly influences the breadth of your academic knowledge, it is impossible to pinpoint a typical LUC career. Fields vary per major and even within the major our alumni choose very divergent paths. To give you a sense of what you can expect, we selected a couple of current jobs or our…

The information below concerns courses that our group teaches in Leiden. 

Launch database

PhD Defence

PhD Defence

LUC graduates have an internationally-recognised Bachelors honours degree (BA/BSc) that qualifies them to apply for competitive programmes at top research universities such as Oxford and Harvard. They may also be eligible for automatic acceptance into one of Leiden’s master programmes!

Promotor: A. Doelman, Co-promotor: V. Rottschäfer

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

Promotor: Prof.dr. D. Bouwmeester, Co-promotor: M.P. van Exter

The Western Mediterranean is a key region to understand human dispersal events within and out of the African continent as well as for the eventual replacement of Neanderthals by anatomically modern humans during the Pleistocene. Central to any conclusive interpretation of archaeological and palaeoclimatic…

Promotor: Prof.dr. D. Bouwmeester, Co-Promotor: M.J.A. de Dood

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

In this working paper, Dr. Joris Larik provides an analysis of the governance and dispute settlement mechanisms under the Ireland/Northern Ireland Protocol.

This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique…

Several alumni, young alumni and students have been matched via the Leiden University Mentor Network.

Promotor: Prof.dr. E.F. van Dishoeck, Co-promotor: S. Bruderer

The focus of the dissertation

Thomas Hansen is our Leiden Institute of Chemistry's nominee for the C.J. Kok Jury Award 2020.

When combined and used by specific people located in time and place, words can express something more than, different from, or even the opposite of their dictionary meanings.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

What are the functions of the endocannabinoid system?

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

In 2015, Leiden University has been awarded an ICM grant for student and staff exchange with eight different partner countries outside Europe. In 2018 this number almost doubled to fourteen. A complete list can be found in the overview section. Here we share a couple of highlights from 2018.

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Spaanse Water

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

On the first day at a new job, you have sweaty palms, nerves race through your system, and you feel insecure. Now, a couple of months later these feelings have left. You know what to do in your new role and have become part of the organization. The process leading to this result is called organizational…

The presence of religious idioms in people’s responses to vulnerability and misfortune is not unique to Aceh, or to Indonesia. Yet the scale of the tsunami coupled with the historically deeply ingrained presence of religion in Acehnese everyday life has magnified religious discourses on misfortune,…

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

We are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

A couple of years ago, theoretical physicist Carlo Beenakker tracked down the Majorana particles and inspired Leo Kouwenhoven from TU Delft to try to create them in a superconducting nano-structure. He succeeded in doing so in 2012, and the news made headlines around the world. But a lot of work still…

Leiden University offers ambitious students the opportunity to gain state-of-the-art knowledge, coupled with the freedom to develop their own area of expertise.

In Quantum mechanics, particles can be in multiple positions simultaneously. Yet, when a measurement is made, the particle is found only in one place. Technology has come to a point where we may design experiments that will tell us how.

To be eligible to register, you must have satisfied the entry requirements or it must be reasonable to assume that you will satisfy these requirements in the near future.