Welcome to the Social Anxiety and Specific Phobia (SASP) Research Group!

From basic science to real-world interventions

Can a newly developed, app-based, personalized maintenance program enhance the effectiveness of the exposure-based one-session-treatment for children with a specific phobia?

From basic science to real-world interventions

Our team consists of the following members.

The main focus of our research programme is on adolescence, a key transitional period in human development. The programme puts emphasis on combined experimental behavioural and neural analysis of normative transitions and deviations in adolescent development.

How can we facilitate the early recognition of stress and anxiety in the classroom and collaborate with schools in providing low-threshold interventions?

... studies the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

This dissertation aims at enhancing our knowledge of whether a CI provides sufficient access to auditory speech input to acquire verbal morphology by comparing outcomes of CI children to those of their normal hearing peers and to those of children with specific language impaired (SLI).

Our team is involved in the translation and adaptation of several questionnaires, for research purposes. Information about each questionnaire is listed below.

In Film and Video Intermediality, Janna Houwen innovatively rewrites the concept of medium specificity in order to answer the questions “what is meant by video?” and “what is meant by film?”

The ‘empathic mind’ in children with Specific Language Impairments (SLI); what can children with SLI understand of other people’s minds and emotions?

Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

Promotor: Prof.dr. G.R. de Snoo, Co-promotores: Dr. ing. M.G. Vijver, J.P.M. Vink

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Schneider

In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.

In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.

The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…

For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…

There have been indications for decades that there is a link between increased iron levels in the brain and Alzheimer’s disease. Leiden physicists find this connection as well, thereby now making a distinction between different forms of iron. They identify specific iron forms that increase in Alzheimer’s…

The new Dutch government must act quickly to take rapid, far-reaching measures in three specific regions to tackle nitrogen emissions. This will create the space for a long-term strategy to deal with other urgent problems and the knot of obligations that the state will need to untangle. These are the…

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Promotor: Prof.dr. W.T.F. den Hollander, Prof. dr. E.A. Verbitskiy

Our research regularly receives attention in the (Dutch) popular media. Here is an overview.

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Promotor: Prof.dr. G.J. Kroes

PhD Defence

PhD Defence

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

PhD Defence

PhD Defence

PhD Defence

PhD Defence

PhD Defence

PhD Defence

Previous research has shown that extreme shyness is hereditary, but because shyness is such a broad concept it is difficult to identify specific genes. Anita Harrewijn has discovered particular brain measurements that can help. PhD defence 18 January.

PhD Defence

Lecture, Areal Histories

PhD Defence