We investigate emergent structures and dynamics of soft materials self-assembled from microscopic constituents.

Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Develop EPR instrumentation and methodology to investigate intrinsically disordered proteins (IDPs).

This thesis describes a study from both a theoreticaL and an experimental point of view.

Dr. Pauline Aarten tries to find answers of the impact a road traffic accident has on the victims and surviving relatives and how we can improve their position.

How do genetic and environmental factors make us vulnerable to depression?

Toward optimal measurement and greater understanding of youth cognition in school refusal and cognitive behavioural therapy outcome

What are the circadian disturbances underlying depression vulnerability? How are they related to mood, cognition and sleep ?

The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.

Neurobiological, cognitive and behavioural measurements of normal and abnormal child development.

Welcome to the Social Anxiety and Specific Phobia (SASP) Research Group!

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Are there any differences in gaze behavior between high and low socially anxious individuals? What factors influence the relation between social anxiety and gaze behavior?

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

Consensus and harmony or balance and reciprocity?

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

What are the functions of the endocannabinoid system?

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

The research connected to this topic is related to E-health.

Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

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Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…

The programme of the master specialisation Learning Problems and Impairments studies common learning problems such as dyslexia, hyperlexia and dyscalculia, as well as learning disabilities caused by AHDH, ADD or speech and language disorders. Much attention is also devoted to the relation between brain…

The project Advancing The European Multilingual Experience (AThEME) takes an integrated approach towards the study of multilingualism in Europe by incorporating and combining linguistic, cognitive and sociological perspectives.

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

Legitimacy is generally a term that is associated with the state. The term surfaces when there are problems with state legitimacy—when it is lacking or absent. This present volume attempts to think through the relevance of the concept of legitimacy for other political actors than the state.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.

Lecture

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

Serious forms of anxiety concerning other people’s opinions can hinder teenagers at school in social interactions or carrying out tasks. Psychologist Anne Miers is looking for ways to reduce this so-called ‘social anxiety’.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers. However, there are far more graduates than vacancies, especially in mental health care, and competition is therefore fierc…

In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

The research carried out within the unit Health, Medical and Neuropsychology investigates the psychological factors of health and disease, and the development of innovative treatment.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Previous research has shown that extreme shyness is hereditary, but because shyness is such a broad concept it is difficult to identify specific genes. Anita Harrewijn has discovered particular brain measurements that can help. PhD defence 18 January.

The Hague is the international city of peace and justice, home to many international organisations, embassies and multinational corporations but also a fun student city filled with music, cafes, museums and the most popular beach in the Netherlands!

The Hague is the international city of peace and justice, home to many international organisations, embassies and multinational corporations but also a fun student city filled with music, cafes, museums and the most popular beach in the Netherlands!

The Hague is the international city of peace and justice, home to many international organisations, embassies and multinational corporations but also a fun student city filled with music, cafes, museums and the most popular beach in the Netherlands!

The ‘empathic mind’ in children with Specific Language Impairments (SLI); what can children with SLI understand of other people’s minds and emotions?

Is blended care a feasible and effective treatment method for social anxiety in adolescence?

The Hague is the international city of peace and justice, home to many international organisations, embassies and multinational corporations but also a fun student city filled with music, cafes, museums and the most popular beach in the Netherlands!

Master projects are available in