1,657 search results for “solid phase synthesis” in the Public website
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Physics (BSc)
Studying Physics is an exciting journey through the foundations of nature: from the infinitesimal (particle physics) to the grandest scale (cosmology). Physics is a varied study programme that provides a solid foundation in theory and experimentation, with attention devoted to their practical applic…
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Exploring Images With Deep Learning for Classification, Retrieval and Synthesis
PhD Defence
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Novel Protecting Group Strategies in the Synthesis of Oligosaccharides
PhD Defence
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Synthesis and application of glycans unique to S. Mansoni
PhD Defence
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Chemical Synthesis of Fragments of Galactosaminogalactan and Pel Polysaccharides
PhD Defence
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The Synthesis of Chemical Tools for Studying Sphingolipid Metabolism
PhD Defence
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
PhD Defence
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Iminosugars as glucosylceramide processing enzyme inhibitors: design, synthesis and application
PhD Defence
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Total Synthesis of Alginate and Zwitterionic Sp1 Oligosaccharides
PhD Defence
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Synthesis of well-defined ADP-ribosylated biomolecules
PhD Defence
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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To the Euphrates and Beyond
The wide-ranging interests of the Dutch archeologist Maurits van Loon -prehistory, art history, and ancient history - are reflected in these papers, which commemorate his 30 years of archeological research in the Near East
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Bioactive Molecules
Bioactive Molecules is one of the four research themes of the Institute of Biology Leiden.
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The Role of Law in Libya’s National Reconciliation
The Role of Law in Libya’s National Reconciliation (RoLLNaR) was a research project that ran from 2017 to 2020. It identified and assessed the role of law – both actual and potential, enabling and constraining – with regard to major challenges of reconciliation in Libya. The project was led by Dr. Suliman…
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The style of speeches
What is the difference between a minister saying that something is possible or that it is not impossible ?
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About the project
The new building for the Faculty of Science represents an important milestone, both for Leiden University in general and for the faculty in particular. The new building will be built in three phases. The first phase of the new building was brought into use in 2016 and covers 45,000 m2. The first phase…
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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Hit Discovery
The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.
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Supramolecular materials: from biosensors to cell delivery devices
The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…
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PhD Theses
A full overview of BPOC/SSNMR PhD theses.
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Geometric Phases in Soft Materials
PhD Defence
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The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations.
The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations. Hans Slabbekoorn, associate professor at the IBL, is the principal investigator and collaborates with three PhD-students, Dr. Erwin Winter, (Wageningen Marine Research),…
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Research
Research at the BPOC/SSNMR group is comprised of the following research themes:
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NMR Facility
Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…
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Why Leiden University
Do you aspire to a national or international career in law? Then choose the master’s programme Law - European Law - at Leiden University: a broad and solid foundation for your career.
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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The astrochemical factory: A solid base for interstellar reactions
PhD Defence
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Career prospects
Create a world of opportunities with a master's degree from Leiden University
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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History (BA)
Are you fascinated by the past and do you like to challenge yourself? In the Dutch-taught Bachelor's programme History at Leiden University you will approach the past with a sharp and analytic view and you will learn to look at the past from a completely new perspective. study the history of the ancient…
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Development of novel analytical technologies for metabolomics and systems pharmacology
We are aiming to develop novel technologies to allow better sample preparation or coupling of analytical methods to (i) analyse ultra small samples, (ii) to analyse more metabolites in a quantitative manner and/or (iii) increase the sample throughput.
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Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
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Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
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Our technology: Cathodic Corrosion Method (CCM)
Cathodic corrosion for producing nanoparticles was (re)discovered when trying to control the electrochemical etching of a scanning tunneling microscopy (STM) tip.
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Times fade away
The neolithization of the southern Netherlands in an antropological and geographical perspective
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Research
Research at the MCBIM group is comprised of the following research themes:
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Tales from the European borderlands. A comparative analysis of perspectives, expectations and fears of managing cross-border mobility in Europe
To what extent are there differences between countries in and outside the European Union and the Schengen area in the level of crimmigration, the merger between migration control and crime control, and to what extent can these differences be explained by the way in which state and non-state actors in…
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Anisotropic Colloids
While colloidal aggregates are often undesirable due to their random shapes, we exploit them as a starting point to synthesize patchy particles.
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ReCiPe
The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).
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Novel approaches for direct exoplanet imaging: theory, simulations and experiments
The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.
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Research Support Portal & Leiden Open Science
Leiden University offers support in the different stages of your research lifecycle.
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Stromal cells suppress immune response symptoms
A new therapy for the serious Graft-versus-Host disease
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Alumni
Former PhD, Bachelor and Master students of the Van Exter Lab
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Luca Giomi wins ERC Consolidator Grant for flowing cells
Theoretical physicist Luca Giomi receives a 2 million euro ERC Consolidator Grant for research into flowing cells in a strange hexatic phase, which is half fluid, half solid.
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Current studies
We always have several ongoing studies running in our labs. Below you can find information about each one.
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Gorlaeus Bicycle Storage
The sustainable demolition of the Gorlaeus high-rise of the Faculty of Science is now complete. This demolition is part of the redevelopment of the faculty. A part of the steel construction will form the basis of a new green bike park.
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Sustainable demolition
Several buildings need to be demolished to make way for phase 2.
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Exploring the life of amulets in Palestine
On the 1st of December Marcela A. Garcia Probert successfully defended a doctoral thesis and graduated.