1,682 search results for “solid phase oligosaccharide synthesis” in the Public website
- Leiden Observatory
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Campus square
Over the coming years, the Leiden Bio Science Park will be transformed from a business park into a campus. The campus square will be the vibrant heart of this area. Here, the university, businesses and the city of Leiden get together.
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Optimal Teaching
The better teaching is for pupils and students, the more solid the basis will be that we give them for their future careers. This type of teaching requires strong instructors and insight into the best ways in which pupils can be supported, and research at Leiden University is making a contribution in…
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Biochemistry in different phases of the migraine attack
PhD Defence
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3D Image to Characterize and Optimize antibody-mediated antitumor immunity
Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli
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About
The Institute of Public Administration is one of the largest and oldest institutes of academic research and teaching in the field of public administration in the Netherlands. The Institute combines a solid international academic reputation with a central positioning among the international, national,…
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Oxidation of Therapeutic Proteins and Peptides: Structural and Biological Consequences
Oxidation is a common degradation pathway that affects therapeutic proteins and peptides during production, purification, formulation, transportation, storage and handling of solid and liquid preparations. In the present work we review the scientific literature about structural and biological consequences…
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Quan/Qual analysis of drugs and metabolites in biological matrices
Can we develop a generic method for Quan/Qual analysis of small molecule drugs, their metabolites and endogenous metabolites in (pre-)clinical samples?
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Career preparation
The programme International Criminal Law at Leiden University prepares you for a succesful career. Read more about our career preparation activities
- Institute of Urban Environment
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About the programme
The curriculum of this bachelor’s programme gives you an understanding of artificial intelligence and data science with a solid basis in computer science. Both artificial intelligence and data science are broad disciplines that require essential and foundational underpinnings.
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Career preparation
In the programme, we will prepare you for your career. We provide you the knowledge and professional skills to practice public international law.
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Master's application and admission
Find out how to apply for Public International Law at Leiden University by following our step-by-step guide.
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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CWTS
The Centre for Science and Technology Studies (CWTS) is an interdisciplinary research institute at Leiden University that studies scientific research and its connections to technology, innovation, and society.
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Towards Optical Detection of a Single Electron
Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.
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Ecological functions and environmental fate of exopolymers of Acidobacteria
Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.
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Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
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Novel formulations and delivery strategies for inactivated polio vaccines: new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
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Exploring Justice in Extreme Cases: Criminal Law Theory and International Criminal Law
On 12 mei 2020, Darryl Robinson defended 'Exploring Justice in Extreme Cases: Criminal Law Theory and International Criminal Law'. The doctoral research was supervised by Prof. C. Stahn.
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Inform yourself
We would like you to choose your study well-informed and make sure the program meets your expectations. These four points can help you to make a solid decision.
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Student projects
We invite you to develop your academic skills by joining our research group and develop your own short term project in the bachelor phase. We offer longer term research projects for master students.
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Tracing the evolution of protoplanetary disks
Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L.B.F.M. Waters (UvA), Prof.dr. C. Dominik (UvA)
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Research Support Team
The Research Support Team (RST) at the Institute of Security and Global Affairs provides comprehensive support and timely advice to researchers in identifying relevant grant schemes or funding systems.
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Doris Heinrich Lab (Biophysics of Cellular Dynamics)
This research group is interested in the physics of living cells, especially their cytoskeleton dynamics under defined external stimuli.
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Non-canonical gender systems
Grammatical gender is famously the most puzzling of the grammatical categories. We have a solid typology of gender systems, yet exciting and unexpected patterns keep turning up which defy easy classification and straightforward analysis. Some of these question, stretch or threaten to cross the outer…
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors
Promotor: A.P. IJzerman
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Leiden Institute of Chemistry
The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…
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Burning the land
A global synthesis of the extent, diversity and patterns in off-site fire use by historically documented and current hunter-gatherers with the remit of this study in the deeper past.
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Potential interference of fungal endophytes in Vanilla planifolia on vanilla flavor compounds biosynthesis
Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Energy & Sustainability
Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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Research schools in chemistry
The Leiden Institute of Chemistry actively participates in several national research schools for MSc and PhD students. These schools are consortia that stimulate collaboration between research groups of the different participating Dutch universities. The research schools also offer advanced training…
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.
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About the programme
The minor consists of three courses in each period, and a group project running the whole semester. The first period starts off with the three-week course Anthropocene: The Planet of Man, which serves as an introduction into the subject as well as for building a community of students. This course is…
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Institute for Area Studies: Asia & the Middle East
The Leiden University Institute for Area Studies (LIAS) is devoted to the study of places in the human world from antiquity to the present time in a comparative and interdisciplinary perspective.
- Research projects
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Two NWO ECHO grants for Leiden Chemistry
Two excellent young chemists, Jeroen Codée and Sander van Kasteren, have received an ECHO grant for €260,000 from the Netherlands Organisation for Scientific Research (NWO). This funding will allow them to begin their research projects.
- Chemical reactions, corrosion and electrochemistry at solid-liquid interfaces – routine operando studies with Near Ambient Pressure XPS
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It's just a phase: High-contrast imaging with patterned liquid-crystal phase plates to facilitate characterization of exoplanets
PhD Defence
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FRESH Lecture: Molecular Dynamics Simulations of Solid-Liquid Interfaces Using High-Dimensional Neural Network Potentials
Lecture