1,659 search results for “solid phase oligosaccharide synthesis” in the Public website
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The physics of nanowire superconducting single-photon detectors
Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)
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Schipluiden
A neolithic settlement on the Dutch North Sea coast c. 3500 CAL BC.
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Higgs dynamics in the early universe
In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.
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Tom O'Brien
Science
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Chris Hoeboer
Faculteit der Sociale Wetenschappen
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Remko Offringa
Science
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Students kick-off next construction phase of new Gorlaeus building
And the construction has started! Students of the Leiden Science study associations ceremoniously hammered down the first poles of the new Gorlaeus on Tuesday morning. By doing so, they initiated the second phase of the construction of the second part of the new building.
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Applications of topology to Weyl semimetals and quantum computing
This thesis covers various applications of topology in condensed matter physics and quantum information.
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Hamed Abbaszadeh
Science
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Biosyn Talks
PhD students at Bio-organic Synthesis are invited to present their work during the weekly Monday Morning Biosyn Talks.
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CO2 reduction on post-transition metals and their alloys: an industrial approach
This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Chemical Biology Lecture: Chemical Protein Synthesis - Providing Tailor-Made Proteins for Biology and Medicine
Lecture
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John Mydosh and the mystery of the Hidden Order
A 35-year-old uranium crystal will not disclose its secret: what causes a dramatic phase transition at 17.5 Kelvin? Thanks to a new artificial intelligence approach, half of the possible explanations are excluded, but the definitive answer remains to be found. 'It is very frustrating', says physicist…
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Cutaneous barrier dysfunction in atopic eczema: the role of stratum corneum lipids
Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463
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Contact
Contact Biophysical Organic Chemistry/Solid State NMR
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David Doelman
Science
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Voorburg-Arentsburg
In this publication the results of the analyses of the Roman harbour of Voorburg-Arentsburg (NL) are presented. This fully inclusive and integrated study of more than 1000 pages is published in two volumes. The publication is written in Dutch, but has got an extensive synthesis/summary in English.
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Fully funded Ph.D. position – novel chemical modalities
Science, Leiden Academic Centre for Drug Research (LACDR), LACDR PhD Portal
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Metals for Catalysis and Sustainability
Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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Contact
Contact Bio-organic Synthesis
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Noisy Patterns: Bridging the gap between stochastics and dynamics
In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Evidence Synthesis Methods for Continuous Outcomes
PhD Defence
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Theoretical Chemistry
The main goal of the THEOR CHEM group, headed by Prof. Geert-Jan Kroes, is to characterize, and to accurately predict the outcome of chemical reactions at gas-solid and liquid-solid interfaces. Here the solid surface is typically a metal or an ice surface. These goals are important to many areas in…
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Drug Discovery and Safety (MSc)
The master's specialisation Drug Discovery and Safety at Leiden University provides students with research-oriented education into the discovery of new drug targets and new lead molecules, particularly in the field of cancer, through a combination of advanced imaging techniques (‘systems microscopy’),…
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Reagent Controlled Synthesis of 1,2-cis-Oligosaccharides
PhD Defence
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Self adjuvanting immunopeptides: Design and synthesis
PhD Defence
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Synthesis of cyclic peptides as bioconjugation platforms
PhD Defence
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Schedule
The Gorlaeus Building will be constructed in three phases, with the new building due to be completed by 2026.
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Soft condensed matter
What are the mysteries behind soft condensed matter?
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: J.P. Abrahams, Co-Promotor: N.S. Pannu
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Workshop: the mathematics of solid-state physics
Lecture
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About the programme
This multidisciplinary programme offers you the opportunity to study the African continent from many different angles. As a result, you will acquire solid knowledge and understanding of the major historical, cultural, socio-economic and political factors at play in Africa, and learn how to advance this…
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Gorlaeus Building
The first phase of the Gorlaeus Building has been completed and it is in use by the Faculty of Science since 2016. During the second phase we will further develop the building, which will get a nice, characteristic entrance. In September 2021, construction has started.
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GMP facility for innovative drugs (KFT-J10 / IGFL)
The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.
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Inhibitors and probes targeting endo-glycosidases
The chemical synthesis of inhibitors and probes targeting endo-glycosidases.
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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Prince, Pen, and Sword. Eurasian Perspectives
Prince, Pen, and Sword offers a synoptic interpretation of rulers and elites in Eurasia from the fourteenth to the eighteenth century. Four core chapters zoom in on the tensions and connections at court, on the nexus between rulers and religious authority, on the status, function, and self-perceptions…
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
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Reactive Copolypept(o)ides as Novel Material for Systemic siRNA Delivery
The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors
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Topological Phases and Phase Transitions in Magnets and Ice
PhD Defence
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel
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Routes of Exchange, Roots of Connectivity
The archaeology of Afro-Eurasian networks across land and sea (1st millennium CE)
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The synthesis of mannose-derived bioconjugates and enzyme inhibitors
PhD Defence
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Sustainable construction
Just as in phase 1, phase 2 of the Gorlaeus Building will focus on sustainable building.