Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

This meeting will be devoted to recent advances in the operando investigation of reactivity at surfaces from both experimental and theoretical points of view.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.

Science, Leiden Institute of Chemistry (LIC)

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Lecture

The master’s specialisation Research in Physics, Quantum Matter and Optics at Leiden University offers a thorough experience on the front line of physics research with a practical training of communicative and computer skills. The programme focuses on Condensed Matter problems, such as Molecular Electronics,…

Of the 101 Spinoza Prizes that have been awarded since 1995, 25 have gone to researchers from Leiden University. The NWO Spinoza Prize is the highest Dutch award in science. The younger NWO Stevin grant goes to researchers who have achieved great success in the field of knowledge utilisation for society.…

A full overview of CASC PhD theses.

Twee teams of astronomers, including from the universities of Amsterdam and Leiden, have discovered how hot gas giants are surrounded by large halos of thin helium gas, an indication that they are slowly losing their atmosphere. The helium, that was recently seen for the first time by the Hubble space…

The 1st CIGR meeting was held on March 30, 2021, with talks by representatives of all participating groups.

Dr. at Max Planck Institute for chemical Ecology, Jena - Germany

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

PURPOSE: To determine the effect of elasticity on the skin permeation of ketoprofen from surfactant-based vesicular formulations and elastic liposomes.

Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…

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FitDis! is designed to ease the determination of binding energy and oligomeric state of coiled coil peptides. It allows direct fitting of concentration dependent thermal peptide unfolding curves measured for instance by CD–spectroscopy.

Can metabolomic profiling be used to predict resistance against insect herbivores in plants?

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…

The Leiden Institute of Chemistry actively participates in several national research schools for MSc and PhD students. These schools are consortia that stimulate collaboration between research groups of the different participating Dutch universities. The research schools also offer advanced training…

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Psycholinguistic research

PhD Defence

A full overview of BPOC/SSNMR PhD theses.

Lecture

The Dutch-Japanese made DESHIMA instrument has passed its first practical tests when measuring the distances and ages of distant galaxies. The core of the instrument is a chip the size of two euro coins that measures 49 shades of far infrared light. The developers of the spectrometer publish the results…

Lecture

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

After 25 years, December will finally see the launch of the long-awaited James Webb space telescope. Leiden astronomers are watching with great excitement: not only were they involved in the construction of important instruments on board, the telescope will also reveal many new secrets of the universe,…

Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…

In our lab, we investigate the physics and material properties of low-dimensional systems.

Research at the Catalysis and Surface Chemistry group is comprised of the following research themes:

Coordination chemistry is the chemistry of metal atoms

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars, which are called exo-planets. They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems.…

Which metabolites of sponge are influenced by individual environmental or biological factors?

In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit.

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars (exoplanets). They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems. This way they address…

Research at the Macromolecular Biochemistry group is comprised of the following research themes:

Rottgering

These are the proposed research projects for LEAPS 2019. Please note that not all projects will go ahead and some may still be added in the near future. Final funding decisions lie with the Faculty sponsors. And please make a note that if you are interested in an ESA project, to check if your state…

Science, Institute of Biology Leiden (IBL)