We review the state-of-the-art in the theory of dissociative chemisorption (DC) of small gas phase molecules on metal surfaces, which is important to modeling heterogeneous catalysis for practical reasons, and for achieving an understanding of the wealth of experimental information that exists for this…

Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.

The

Twenty years from now, the world population is estimated to be around 9 billion people (now 8 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables, water and energy.…

PhD defence

Leiden University is developing new short stay living space for foreign guests and employees. De Kloksteeg is currently the last of four projects that has been renovated by the Leiden University Real Estate directorate since 2017. The Service Centre International Staff (SCIS) is responsible for rental…

When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…

Promotor: Prof.dr. J. Brouwer, Co-promotor: Dr. Remus Th. Dame

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Promotor: Prof.dr. S. Haring

Is it possible for sugar patterns on cells to activate the immune system to combat cancer?

PhD defence

PhD defence

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

Koper

Advancing the understanding of the interaction of light and matter on the single-quantum level is important for near-future quantum technologies but also to answer fundamental questions.

A common assumption in chemistry is that the coordination number of a catalyst's surface determines the reactivity of the reaction it catalyses. Strikingly, Leiden chemists have now proven that this is not true for nature’s most simple chemical reaction: the dissociation of hydrogen. The researchers…

An overview of our infrastructure at the SPP division:

A 24 person classroom on the ground floor of PJ Vethgebouw. Rolling, flexible furniture and 5+ writable surfaces supports small groupwork. Furniture is interlocking, supporting multiple arrangments. Features a smartboard TV monitor. Bookable through ZRS.

Lecture

Lecture

Lecture

On September 12, Michel Orrit received his Spinoza prize in the Royal Theatre in The Hague from OCW Secretary of State Sander Dekker. With the award comes a budget of 2.5 million euro, to be spent freely on scientific research, and the coveted Spinoza statue. Orrit shared the honor with Eveline Crone…

Michel Orrit was awarded the Physica prize 2016 for his groundbreaking work on single molecule spectroscopy.

Lecture

Lecture

Visualising cell proteins without invasive techniques is possible with the help of fluorescence. During a lecture of the Natuurwetenschappelijk Gezelschap Leiden on 18 January, winner of the Spinoza Prize 2017 and founder of the field of single molecule optics Michel Orrit explained how this works.

Lecture

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Nonadiabatic energy transfer from the translational motion (T) of a molecule impinging on metal surface to the metal’s electrons may determine whether the molecule can lose enough energy to adsorb or react.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Promotor: A. Kros

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

To study how planetary systems come into existence we study much younger systems still in formation.

Recent studies of Neandertal body mass and skin surface indicate raised energetic requirements in this lineage compared to anatomically modern humans.

Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.

Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Here you will find an overview of the Spaces for Active Teaching and Learning already implemented at Leiden University and LUMC. These rooms vary in size, location, material affordances, and technological affordances, and thus vary in the forms of pedagogy they best support. You can use this site as…

Lecture

PhD defence

The central theme of Rik Mom’s research group is to identify what the electrode-electrolyte interface looks like when electrocatalysis is taking place. Using specialized forms of Raman and X-ray spectroscopy, we study the chemical state and bonding environment of the electrode surface and near-surface…

Assessing the effects of landscape and land-use changes on the visibility of archaeological landscapes in Central-Southern Italy.

Nematic liquid crystals form the key ingredients of most tv screens. The active version of these complex fluids forms a useful model for physicists to research the responses of active matter—like bacteria or traffic flows—to mechanical and geometrical cues. An international research team publishes their…