178 search results for “ruthenium polypyridyl complexes” in the Public website
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Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Light-activatable ruthenium-based anticancer prodrugs
Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Caging ruthenium complexes with non-toxic ligands for photoactivated chemotherapy
The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.
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Molecular and Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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PhD Theses
A full overview of MCBIM PhD theses.
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Breaking of ensemble equivalence for complex networks
For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.
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Mononuclear spin-transition materials based on the bapbpy scaffold
Promotor: E. Bouwman, Co-Promotor: S. Bonnet
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Many objective optimization and complex network analysis
This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.
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Is Michael Meijer the Smartest Chemist of the Netherlands?
He is occupied with the home stretch of his promotion. But in between, there is another challenge: Michael Meijer is going through to the finals of ‘The Smartest Chemist of the Netherlands’. On Tuesday 9 October, he and five others fight for this title during the Evening of Chemistry. ‘I was dragged…
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Bugs and birds and landscape complexity
What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?
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Complex Patterns in Streams
The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…
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Complex multiplication of abelian surfaces
Promotor: Peter Stevenhagen
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Dual Complexes of Semistable Varieties
This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.
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Correlates of Complexity
Essays in Archaeology and Assyriology Dedicated to Diederik J.W. Meijer in Honour of his 65th Birthday
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Ten years ERC: Sylvestre Bonnet kills cancer with light
In 2013, Sylvestre Bonnet received an ERC Starting Grant to kill cancer with molecules that can be activated by light. Two postdocs and three PhD students later, the end approaches of his so far successful project.
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Leiden Complex Networks Network (LCN2)
The Leiden Complex Networks Network (LCN2) aims at bringing together scientists from different disciplines, based on a common interest in both theoretical models and empirical analyses of networks and graphs.
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Diversity in the globally intertwined giant barrel sponge species complex
This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.
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Biological, Soft and Complex Systems
We study the physics of a broad range of biological and soft materials
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Understanding the complexity of intelligence problems
The complexity of an intelligence problem determines to a great extent the certainty that can be provided by intelligence and security services.
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Copper trispyrazolylborate complexes for ethene detection
Promotor: E. Bouwman Co-Promotor: S. Bonnet
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Probing complex problems
Issues such as climate change, the depletion of natural resources or social inequality are too complex to be addressed from a single scientific discipline or by a single country. Leiden University has the expertise to bring the resolution of these enormous problems a small step closer.
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Mining Sensor Data from Complex Systems
Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe
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Biomimetic Copper Complexes for Energy Conversion Reactions
Hetterscheid
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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Bayesian uncertainty quantication in complex models
The aim of this project is to determine in which cases uncertainty statements resulting from a Bayesian statistical analysis can be trusted.
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Towards in-cell structural study of light-harvesting complexes : an investigation with MAS-NMR
Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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Hidden Complexities of the Frankish Castle
Social Aspects of Space in the Configurational Architecture of Frankish Castles in the Holy Land, 1099-1291
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The Saint-Servatius complex in Maastricht
The Vrijthof excavations (1969-1970)
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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The international tax system as a complex system
Complex systems can be characterized as systems in which multiple components interact with each other, often in non-linear ways. The main goal of this research will be to investigate if and how the international tax system can be defined and modelled as a complex system. Approaching the international…
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addition reactions in interstellar ice - new pathways towards molecular complexity in space -
Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen
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1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
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Biomimetic redox reactions of the Cu(II) μ-thiolate complex
Promotor: Prof.dr. E. Bouwman
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Oxidation catalysis on Pt and Au: complexity of simple chemistry
Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink
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The Metallophilic Interaction between Cyclometalated Complexes: Photobiological Applications
PhD Defence
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Blowup in the complex Ginzburg-Landau equation
Promotor: A. Doelman, Co-promotor: V. Rottschäfer
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of productive and futile encounters in an electron transfer protein complex
PNAS publication on protein encounter complexes
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Determining the structure of a chemotaxis kinase complex with receptor mimetics and cryo-EM
Can we determine the 3D structure of a chemotaxis core complex using single-particle reconstructions via cryo-EM?
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The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
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Inextricable ties between chemical complexity and dynamics of embedded protostellar regions
Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh
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The formation of complex organic molecules in dense clouds-Sweet results from laboratory
Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.