12 search results for “rnai” in the Public website
Maurijn van der Zee
Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
Unravelling cancer drug resistance mechanisms
Mechanisms fro drug resistance
Therapeutic RNAi-based gene therapy for neurodegenerative disorders
How insects conquered land
IBL-researchers revealed in a new study that insects are successful on land because their eggs became protected against desiccation. An extraembryonic membrane in the egg, the serosa, helped insects to make the transition from water to land.
RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
The serosa: an evolutionary novelty in insect eggs
What is the function of the insect serosa?
Reactive Copolypept(o)ides as Novel Material for Systemic siRNA Delivery
The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors
Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
An overview of the research at the Cancer Dug Target Discovery group.
PROPER: ‘Near-patient’ prostate cancer models for the assessment of disease prognosis and therapy
How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?
Myosin motors drive cytoplasmic streaming, cell growth and plant development
Lecture, Van Leeuwenhoek Lecture on BioScience